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  1. This study evaluated the effect of pomegranate seed oil (PSO) supplementation, rich in punicic acid (55 %/C18:3-9c,11 t,13c/CLNA), on the lipid profile and on the biochemical and oxidative parameters in the gastr...

    Authors: Illana Louise Pereira de Melo, Ana Mara de Oliveira e Silva, Eliane Bonifácio Teixeira de Carvalho, Luciana Tedesco Yoshime, José Augusto Gasparotto Sattler and Jorge Mancini-Filho
    Citation: Lipids in Health and Disease 2016 15:40
    Content type: Research Published on:

  2. Chicken as a delicious food for a long history, and it is well known that excess fat deposition in broiler chickens will not only induced metabolic diseases, but also lead to adverse effect in the consumer’s h...

    Authors: Jing Han, Longlong Li, Dian Wang and Haitian Ma
    Citation: Lipids in Health and Disease 2016 15:37
    Content type: Research Published on:

  3. Recent evidence has demonstrated that the G0/G1 switch gene 2 (G0S2) is an important negative regulator of the rate-limiting lipolytic enzyme adipose triglyceride lipase-mediated lipolysis. It has been reveale...

    Authors: Naiqian Zhao, Li Wang and Na Guo
    Citation: Lipids in Health and Disease 2016 15:36
    Content type: Research Published on:

  4. As the major storage site for triglycerides and free cholesterol, adipose tissue plays a central role in energy metabolism. ApoA-I is the main constituent of HDL and plays an important role in removal of exces...

    Authors: Shuai Wang, Dao-quan Peng and Yuhong Yi
    Citation: Lipids in Health and Disease 2016 15:35
    Content type: Review Published on:

  5. Apolipoprotein E (apoE) induces the uptake of vitamin K-rich lipoproteins by the liver, which likely affects inter-individual variation of warfarin dosing requirements. Associations between APOE polymorphisms and...

    Authors: Rui Liu, Kui Zhang, Zhi-zhong Gong, Xin-miao Shi, Qian Zhang, Xiao-dong Pan and Ran Dong
    Citation: Lipids in Health and Disease 2016 15:34
    Content type: Research Published on:

  6. Atherosclerosis is a common pathological basis of cardiovascular disease. Adiponectin (APN) has been shown to have an anti-atherosclerosis effect, and the underlying mechanisms, however, are largely unknown. N...

    Authors: Xuemei Wang, Qingjie Chen, Hongwei Pu, Qin Wei, Mingjun Duan, Chun Zhang, Tao Jiang, Xi Shou, Jianlong Zhang and Yining Yang
    Citation: Lipids in Health and Disease 2016 15:33
    Content type: Research Published on:

  7. A plant-based strategy to improve long-chain (LC) omega (n)-3 PUFA supply in humans involves dietary supplementation with oils containing α-linolenic acid (ALA) alone or in combination with stearidonic acid (S...

    Authors: Katrin Kuhnt, Stefanie Weiß, Michael Kiehntopf and Gerhard Jahreis
    Citation: Lipids in Health and Disease 2016 15:32
    Content type: Research Published on:

  8. N-3 and N-6 polyunsaturated fatty acids are widely used in reproduction, yet few studies have addressed the effects of dietary n-6/n-3 ratios on boar reproduction. The present study aimed to determine the effe...

    Authors: Yan Lin, Xu Cheng, Jiude Mao, De Wu, Bo Ren, Sheng-Yu Xu, Zheng-Feng Fang, Lian-Qiang Che, Cai-Mei Wu and Jian Li
    Citation: Lipids in Health and Disease 2016 15:31
    Content type: Research Published on:

  9. Total polar compounds (TPC) formed during successive frying have the negative healthy effects. However, little researches focused on the cytotoxicity of different parts of TPC. The present study was carried ou...

    Authors: Jinwei Li, Xiaodan Li, Wenci Cai and Yuanfa Liu
    Citation: Lipids in Health and Disease 2016 15:30
    Content type: Short report Published on:

  10. The FTO gene has recently become one of the most extensively investigated genes associated with body mass and has been shown to play a role in cardiovascular diseases as well. The aim of the current study was to ...

    Authors: Saleem Ullah Shahid, Shabana, Abdul Rehman and Shahida Hasnain
    Citation: Lipids in Health and Disease 2016 15:29
    Content type: Research Published on:

  11. The effect of alirocumab on potentially atherogenic lipoprotein subfractions was assessed in a post hoc analysis using the vertical auto profile (VAP) method.

    Authors: Peter P. Toth, Sara C. Hamon, Steven R. Jones, Seth S. Martin, Parag H. Joshi, Krishnaji R. Kulkarni, Poulabi Banerjee, Corinne Hanotin, Eli M. Roth and James M. McKenney
    Citation: Lipids in Health and Disease 2016 15:28
    Content type: Research Published on:

  12. The incidence of non-alcoholic fatty liver disease (NAFLD), commonly associated with obesity and metabolic syndrome, is increasing worldwide. However, the specific mechanisms that mediate the progression from ...

    Authors: Jiali Liu, Lina Han, Leilei Zhu and Yerong Yu
    Citation: Lipids in Health and Disease 2016 15:27
    Content type: Research Published on:

  13. ANGPTL8 (betatrophin) has been recently identified as a regulator of lipid metabolism through its interaction with ANGPTL3. A sequence variant in ANGPTL8 has been shown to associate with lower level of Low Den...

    Authors: Mohamed Abu-Farha, Motasem Melhem, Jehad Abubaker, Kazem Behbehani, Osama Alsmadi and Naser Elkum
    Citation: Lipids in Health and Disease 2016 15:26
    Content type: Research Published on:

  14. A body of translational evidence has implicated dietary deficiency in long-chain omega-3 (LCn-3) fatty acids, including eicosapenaenoic acid (EPA) and docosahexaenoic acid (DHA), in the pathophysiology and potent...

    Authors: Erik Messamore and Robert K. McNamara
    Citation: Lipids in Health and Disease 2016 15:25
    Content type: Review Published on:

  15. Hepatic mitochondrial dysfunction plays an important role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Methyl donor supplementation has been shown to alleviate NAFLD, connecting the condit...

    Authors: Rolf K. Berge, Bodil Bjørndal, Elin Strand, Pavol Bohov, Carine Lindquist, Jan Erik Nordrehaug, Asbjørn Svardal, Jon Skorve and Ottar Nygård
    Citation: Lipids in Health and Disease 2016 15:24
    Content type: Research Published on:

  16. Emerging evidence suggested phytosterol esters (PE) exhibited an advantage over naturally occurring phytosterols in reducing atherosclerosis risk factors due to improved fat solubility and compatibility. Howev...

    Authors: Qianchun Deng, Xiao Yu, Jiqu Xu, Xiuying Kou, Mingming Zheng, Fenghong Huang, Qingde Huang and Lan Wang
    Citation: Lipids in Health and Disease 2016 15:23
    Content type: Research Published on:

  17. The prevalence of chronic kidney disease is rising continuously. Cardiovascular disease is among leading causes of death and premature mortality of patients with chronic kidney disease. Even the earliest stage...

    Authors: Anna Gluba-Brzózka, Marta Michalska-Kasiczak, Beata Franczyk, Marek Nocuń, Peter P. Toth, Maciej Banach and Jacek Rysz
    Citation: Lipids in Health and Disease 2016 15:22
    Content type: Research Published on:

    The Erratum to this article has been published in Lipids in Health and Disease 2016 15:62

  18. Circumstantial evidence suggests that conjugated linoleic acid (CLA) beneficially modulates immune function in allergic subjects. C9,t11-CLA, naturally occurring in ruminant fats, is suggested to be the effective...

    Authors: Anke Jaudszus, Jochen G. Mainz, Sylvia Pittag, Sabine Dornaus, Christian Dopfer, Alexander Roth and Gerhard Jahreis
    Citation: Lipids in Health and Disease 2016 15:21
    Content type: Research Published on:

  19. Intake of fish oil rich in n-3 polyunsaturated fatty acids (PUFAs) is believed to be beneficial against development of non-alcoholic fatty liver disease (NAFLD). However, the underlying mechanisms remain uncle...

    Authors: Fahu Yuan, Hualin Wang, Yu Tian, Qi Li, Lei He, Na Li and Zhiguo Liu
    Citation: Lipids in Health and Disease 2016 15:20
    Content type: Research Published on:

  20. The 3D structure and functions of ENPP4, a protein expressed on the surface of Bacillus Calmette–Guerin (BCG)-activated macrophages, are unknown. In this study, we analyzed the 3D structure of ENPP4 and determ...

    Authors: Dongmei Yan, Weiwei Han, Zehua Dong, Qihui Liu, Zheng Jin, Dong Chu, Yuan Tian, Jinpei Zhang, Dandan Song, Dunhuang Wang and Xun Zhu
    Citation: Lipids in Health and Disease 2016 15:19
    Content type: Research Published on:

  21. Plasma levels of high-density lipoprotein cholesterol (HDL-C) have been associated to cardiovascular disease. The high heritability of HDL-C plasma levels has been an incentive for several genome wide associat...

    Authors: Marco Cavalli, Gang Pan, Helena Nord and Claes Wadelius
    Citation: Lipids in Health and Disease 2016 15:18
    Content type: Short report Published on:

  23. The aims of this study were to evaluate the effect of poloxamer 407 administration on atherogenic serum lipoprotein fractions and subfractions associated with cholesterol, triglycerides and phospholipids, as well...

    Authors: Tatyana A. Korolenko, Thomas P. Johnston, Fedor V. Tuzikov, Natalia A. Tuzikova, Alexandr B. Pupyshev, Victor K. Spiridonov, Natalya V. Goncharova, Igor V. Maiborodin and Natalia A. Zhukova
    Citation: Lipids in Health and Disease 2016 15:16
    Content type: Research Published on:

  25. Endothelial dysfunction is considered an early step of atherosclerotic vascular disease. Asymmetric dimethylarginine (ADMA), the main endogenous inhibitor of nitric oxide synthase (NOS), plays a critical role ...

    Authors: Mauro Sergio Martins Marrocos, Andrei Alkmin Teixeira, Beata Marie Quinto, Silmara de Melo Carmona, Mariana Kuniyoshi, Cassio Jose Rodrigues, Maria Aparecida Dalboni, Silvia Manfredi, Maria Eugênia Canziani and Marcelo Costa Batista
    Citation: Lipids in Health and Disease 2016 15:14
    Content type: Research Published on:

  26. Sphingolipids, a group of lipids containing the sphingoid base, have both structural and biological functions in human epidermis. Ceramides, as a part of extracellular lipids in the stratum corneum, are import...

    Authors: Sonia Borodzicz, Lidia Rudnicka, Dagmara Mirowska-Guzel and Agnieszka Cudnoch-Jedrzejewska
    Citation: Lipids in Health and Disease 2016 15:13
    Content type: Review Published on:

  27. The severe forms of hypertriglyceridemia are usually caused by genetic defects. In this study, we described a Chinese female with severe hypertriglyceridemia caused by a novel homozygous mutation in the APOC2 ...

    Authors: Jingjing Jiang, Yuhui Wang, Yan Ling, Abudurexiti Kayoumu, George Liu and Xin Gao
    Citation: Lipids in Health and Disease 2016 15:12
    Content type: Research Published on:

    The Erratum to this article has been published in Lipids in Health and Disease 2016 15:42

  28. The inflammatory process seen in inflammatory bowel disease (IBD) is due to excess production of pro-inflammatory cytokines interleukin-1 (IL-1), IL-6, tumor necrosis factor-α (TNF-α), interferons (IFNs), macr...

    Authors: Undurti N. Das
    Citation: Lipids in Health and Disease 2016 15:11
    Content type: Hypothesis Published on:

  29. Impaired glucose regulation (IGR) and hyperlipidemia (HL) are associated with an increased risk of developing a cardiovascular disease. Hyperlipidemic patients were shown to bear a greater risk for an increase...

    Authors: Michael Leutner, Christian Göbl, Alice Wielandner, Eleonora Howorka, Marlies Prünner, Latife Bozkurt, Oliver Schlager, Silvia Charwat-Resl and Alexandra Kautzky-Willer
    Citation: Lipids in Health and Disease 2016 15:10
    Content type: Research Published on:

  30. Cholesteryl ester transfer protein (CETP) is a plasma protein that mediates the exchange of triglycerides for esterified cholesterol between HDL and apoB-lipoproteins. Previous studies suggest that CETP may mo...

    Authors: Helena F. Raposo, Emerielle C. Vanzela, Jairo A. Berti and Helena C F Oliveira
    Citation: Lipids in Health and Disease 2016 15:9
    Content type: Research Published on:

  31. The Neurocan-cartilage intermediate layer protein 2 (NCAN-CILP2) region forms a tight linkage disequilibrium (LD) block and is associated with plasma lipid levels and non-alcoholic fatty liver disease (NAFLD) in ...

    Authors: Supichaya Boonvisut, Kazuhiro Nakayama, Saho Makishima, Kazuhisa Watanabe, Hiroshi Miyashita, Munkhtulga Lkhagvasuren, Yasuo Kagawa and Sadahiko Iwamoto
    Citation: Lipids in Health and Disease 2016 15:8
    Content type: Research Published on:

  32. Several single nucleotide polymorphisms (SNPs) in lipid transport genes have been shown to be associated with premature coronary artery disease (PCAD). The scavenger receptor BI (SCARB1) is a key component of ...

    Authors: Hamidreza Goodarzynejad, Mohammadali Boroumand, Mehrdad Behmanesh, Shayan Ziaee and Arash Jalali
    Citation: Lipids in Health and Disease 2016 15:7
    Content type: Research Published on:

  33. Coronary Heart Disease (CHD) is one of the leading causes of death in the world with a projected global 82 million DALYs by 2020. Genetic and environmental factors contribute to CHD development. Here, the auth...

    Authors: Joseph Sam Kanu, Yulu Gu, Sun Zhi, Mingxi Yu, Yuping Lu, Yetong Cong, Yunkai Liu, Yong Li, Yaqin Yu, Yi Cheng and Yawen Liu
    Citation: Lipids in Health and Disease 2016 15:6
    Content type: Research Published on:

  34. Fatty acid-binding protein 4 (FABP4/A-FABP/aP2) mainly expressed in adipocytes is secreted and acts as an adipokine. Increased circulating FABP4 level is associated with obesity, insulin resistance and atheros...

    Authors: Masato Furuhashi, Shinya Hiramitsu, Tomohiro Mita, Akina Omori, Takahiro Fuseya, Shutaro Ishimura, Yuki Watanabe, Kyoko Hoshina, Megumi Matsumoto, Marenao Tanaka, Norihito Moniwa, Hideaki Yoshida, Junnichi Ishii and Tetsuji Miura
    Citation: Lipids in Health and Disease 2016 15:5
    Content type: Research Published on:

  35. Diet and obesity are recognized in the scientific literature as important risk factors for cancer development and progression. Hypercholesterolemia facilitates lymphoma lymphoblastic cell growth and in time tu...

    Authors: Michela Codini, Samuela Cataldi, Andrea Lazzarini, Anna Tasegian, Maria Rachele Ceccarini, Alessandro Floridi, Remo Lazzarini, Francesco Saverio Ambesi-Impiombato, Francesco Curcio, Tommaso Beccari and Elisabetta Albi
    Citation: Lipids in Health and Disease 2016 15:4
    Content type: Research Published on:

  36. Emerging studies indicate that B-type natriuretic peptide (BNP), a well-known biomarker for heart failure, also plays pivotal roles in metabolic control. Circulating BNP levels progressively increase as ages g...

    Authors: Wen-Tao He, Masayuki Mori, Xue-Feng Yu and Tsugiyasu Kanda
    Citation: Lipids in Health and Disease 2016 15:3
    Content type: Research Published on:

  37. Pulmonary adventitial fibroblasts (PAFs) are activated under stress stimuli leading to their differentiation into myofibroblasts, which is involved in vessel remodeling. 15-HETE is known as an important facto...

    Authors: Li Zhang, Yan Chen, Guixia Li, Minggang Chen, Wei Huang, Yanrui Liu and Yumei Li
    Citation: Lipids in Health and Disease 2016 15:2
    Content type: Research Published on:

  38. Prokineticin-2 is confirmed to be involved in the inflammatory process. Inflammation plays an important role in the pathogenesis of metabolic syndrome (MS). However, whether prokineticin-2 is associated with M...

    Authors: Yong Wang, Xiaoyan Guo, Heng Ma, Lin Lu and Ruiyan Zhang
    Citation: Lipids in Health and Disease 2016 15:1
    Content type: Research Published on:

  39. The most important studies and guidelines in the topics of lipid, blood pressure and kidney published in 2015 were reviewed. In lipid research, the IMProved Reduction of Outcomes: Vytorin Efficacy International T...

    Authors: Maciej Banach, Wilbert S. Aronow, Maria-Corina Serban, Jacek Rysz, Luminita Voroneanu and Adrian Covic
    Citation: Lipids in Health and Disease 2015 14:167
    Content type: Review Published on:

  40. Cardiovascular damages poses risks to children with Kawasaki disease (KD). Although hypertriglyceridemia and hypercholesteremia are risk factors of cardiovascular damages, studies on the blood lipid metabolism...

    Authors: Xi Chen, Zhen-Wen Zhao, Lin Li, Xue-Jun Chen, Hui Xu, Jin-Tu Lou, Lin-Jie Li, Li-Zhong Du and Chun-Hong Xie
    Citation: Lipids in Health and Disease 2015 14:166
    Content type: Research Published on:

  41. The cell membrane is a primary and fundamental player in most cellular processes, and fatty acids form a major structural component of cell membranes. The aim of this study was to compare the membrane fatty ac...

    Authors: Paola Poggi, Roberto Mirabella, Simona Neri, Elisa Assirelli, Paolo Dolzani, Erminia Mariani, Philip C. Calder and Alexandros Chatgilialoglu
    Citation: Lipids in Health and Disease 2015 14:165
    Content type: Research Published on:

  42. Rabbits are also herbivores which efficiently convert fodder to food. They are prolific and converter of plant proteins of little...

    Authors: A. A. Adeniji, S. Rumak and R. A. Oluwafemi
    Citation: Lipids in Health and Disease 2015 14:164
    Content type: Research Published on:

    The Retraction Note to this article has been published in Lipids in Health and Disease 2016 15:101

  43. Lipid abnormalities, enhanced inflammation and oxidative stress seem to represent a vicious circle in atherogenesis, and therapeutic options directed against these processes seems like a reasonable approach in...

    Authors: Rolf K. Berge, Marie S. Ramsvik, Pavol Bohov, Asbjørn Svardal, Jan E. Nordrehaug, Espen Rostrup, Inge Bruheim and Bodil Bjørndal
    Citation: Lipids in Health and Disease 2015 14:163
    Content type: Research Published on:

  44. Since chronic apical periodontitis (CAP) appears to be a risk factor for coronary heart disease, the aim of the study was to determine the relationship between the size of CAP lesion and inflammatory markers (...

    Authors: Aleksandra Kimak, Małgorzata Strycharz-Dudziak, Teresa Bachanek and Elżbieta Kimak
    Citation: Lipids in Health and Disease 2015 14:162
    Content type: Research Published on:

  45. In non-dialysis chronic kidney disease (CKD) patients with dyslipidemia, statin therapy is recommended to prevent cardiovascular complications. Dyslipidemia has been also shown to be an independent risk factor...

    Authors: Masato Ohsawa, Kouichi Tamura, Hiromichi Wakui, Tomohiko Kanaoka, Kengo Azushima, Kazushi Uneda, Sona Haku, Ryu Kobayashi, Kohji Ohki, Kotaro Haruhara, Sho Kinguchi, Yoshiyuki Toya and Satoshi Umemura
    Citation: Lipids in Health and Disease 2015 14:161
    Content type: Research Published on:

  47. Cigarette smoke (CS) exposure impaired plasma lipid profiles by modification of apolipoproteins. Hydrogen (H2) has been proved effective on reducing oxidative stress or improving HDL functionalities in animal mod...

    Authors: Chuanlong Zong, Guohua Song, Shutong Yao, Shoudong Guo, Yang Yu, Nana Yang, Zheng Guo and Shucun Qin
    Citation: Lipids in Health and Disease 2015 14:159
    Content type: Research Published on:

  48. Nonalcoholic fatty liver disease (NAFLD) is a metabolic stress-induced liver disease that is closely related not only to genetic susceptibility but also to insulin resistance and highly linked with metabolic s...

    Authors: Xin Xu, Linlin Lu, Quanyong Dong, Xiaolin Li, Nannan Zhang, Yongning Xin and Shiying Xuan
    Citation: Lipids in Health and Disease 2015 14:158
    Content type: Review Published on:

  49. Exercise is beneficial for blood glucose metabolism. However, whether moderate aerobic exercise could improve impaired fasting glucose is unknown. And the mechanism is also needed to investigate.

    Authors: Huo-cheng Liao, Si-gan Zhong, Peng Li, Wei-bin Chen, Cheng Cheng, Yue-gang Wang, Ping-sheng Wu and Chun Xiao
    Citation: Lipids in Health and Disease 2015 14:157
    Content type: Research Published on:

  50. Pacific saury is a common dietary component in East Asia. Saury oil contains considerable levels of n-3 unsaturated fatty acids (PUFA) and long-chain monounsaturated fatty acids (LCMUFA) with aliphatic tails l...

    Authors: Zhi-Hong Yang, Seika Inoue, Yasuko Taniguchi, Hiroko Miyahara, Yusuke Iwasaki, Jiro Takeo, Hiroshi Sakaue and Yutaka Nakaya
    Citation: Lipids in Health and Disease 2015 14:155
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X