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  1. Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease which represents a wide spectrum of hepatic damage. Several studies have reported that NAFLD is a strong independent risk factor for ...

    Authors: Xiao-Lin Li, Jian-Qing Sui, Lin-Lin Lu, Nan-Nan Zhang, Xin Xu, Quan-Yong Dong, Yong-Ning Xin and Shi-Ying Xuan
    Citation: Lipids in Health and Disease 2016 15:53
    Content type: Review Published on:

  2. The association between serum Retinol Binding Protein 4 (RBP4) and obesity is still controversial. Serum RBP4 levels varies by gender, and estradiol may play a role in the difference. To investigate the partic...

    Authors: Qian Li, Weiyun Wu, Huandong Lin, Xinxia Chang, Hua Bian, Mingfeng Xia, Hongmei Yan and Xin Gao
    Citation: Lipids in Health and Disease 2016 15:52
    Content type: Research Published on:

  3. Recent discoveries of the atherosclerosis-related miRNAs shed new light on the treatment of cardiovascular diseases. Of note, miR-106b ~ 25 cluster and miR-17 ~ 92 cluster are paralogs. Up till now, plenty of ...

    Authors: Ailifeire Maimaiti, Aikebaier Maimaiti, Yining Yang and Yitong Ma
    Citation: Lipids in Health and Disease 2016 15:51
    Content type: Research Published on:

  5. The paucity of data regarding the relationship between atherogenic index of plasma (AIP) and risk of cardiovascular disease (CVD) in postmenopausal women living in sub-Saharan Africa prompted us to conduct thi...

    Authors: Jobert Richie N. Nansseu, Vicky Jocelyne Ama Moor, Murielle Elsa D. Nouaga, Bertrand Zing-Awona, Gladys Tchanana and Arthur Ketcha
    Citation: Lipids in Health and Disease 2016 15:49
    Content type: Research Published on:

  6. Necrotic enteritis (NE), caused by Clostridium perfringens, has cost the poultry industry $2 billion in losses. This study aimed to investigate the effect of Bacillus licheniformis as dietary supplement on the gr...

    Authors: Mengjia Zhou, Dong Zeng, Xueqin Ni, Teng Tu, Zhongqiong Yin, Kangcheng Pan and Bo Jing
    Citation: Lipids in Health and Disease 2016 15:48
    Content type: Research Published on:

  7. Pain management has been considered as significant contributor to broad quality-of-life improvement for cancer patients. Modulating serum cholesterol levels affects analgesia abilities of opioids, important pa...

    Authors: Zhenhua Huang, Lining Liang, Lingyu Li, Miao Xu, Xiang Li, Hao Sun, Songwei He, Lilong Lin, Yixin Zhang, Yancheng Song, Man Yang, Yuling Luo, Horace H. Loh, Ping-Yee Law, Dayong Zheng and Hui Zheng
    Citation: Lipids in Health and Disease 2016 15:47
    Content type: Research Published on:

  8. The distribution of adipose tissue has been evaluated in relation to cardiovascular risk factors and biochemical components of the metabolic syndrome. Neck circumference (NC) has been shown to have a strong re...

    Authors: Yingnan Dai, Xiaojing Wan, Xin Li, Enze Jin and Xueqi Li
    Citation: Lipids in Health and Disease 2016 15:46
    Content type: Research Published on:

  13. Although the prolonged use of rapamycin may cause unwanted side effects such as hyperlipidemia, the underlying mechanism remains unknown. Prox1 is a transcription factor responsible for the development of seve...

    Authors: Sora Kwon, Ji-Sook Jeon, Su Bin Kim, Young-Kwon Hong, Curie Ahn, Jung-Suk Sung and Inho Choi
    Citation: Lipids in Health and Disease 2016 15:41
    Content type: Research Published on:

  14. This study evaluated the effect of pomegranate seed oil (PSO) supplementation, rich in punicic acid (55 %/C18:3-9c,11 t,13c/CLNA), on the lipid profile and on the biochemical and oxidative parameters in the gastr...

    Authors: Illana Louise Pereira de Melo, Ana Mara de Oliveira e Silva, Eliane Bonifácio Teixeira de Carvalho, Luciana Tedesco Yoshime, José Augusto Gasparotto Sattler and Jorge Mancini-Filho
    Citation: Lipids in Health and Disease 2016 15:40
    Content type: Research Published on:

  15. Metabolic syndrome is an increasingly prevalent problem, not only in industrialized developed countries, but in developing countries as well. The modern healthcare to reduce the dysfunction of metabolic syndro...

    Authors: Sara Tariq, Muhammad Imran, Zarina Mushtaq and Nosheen Asghar
    Citation: Lipids in Health and Disease 2016 15:39
    Content type: Research Published on:

  16. Trans fatty acids (TFAs) have been found to impair flow mediated vasodilation and nitric oxide (NO) production. We sought to examine if serum TFA levels are associated with plasma leve...

    Authors: Heidi Borgeraas, Jens Kristoffer Hertel, Reinhard Seifert, Rolf K. Berge, Pavol Bohov, Per Magne Ueland, Ottar Nygård and Jøran Hjelmesæth
    Citation: Lipids in Health and Disease 2016 15:38
    Content type: Research Published on:

  17. Chicken as a delicious food for a long history, and it is well known that excess fat deposition in broiler chickens will not only induced metabolic diseases, but also lead to adverse effect in the consumer’s h...

    Authors: Jing Han, Longlong Li, Dian Wang and Haitian Ma
    Citation: Lipids in Health and Disease 2016 15:37
    Content type: Research Published on:

  18. Recent evidence has demonstrated that the G0/G1 switch gene 2 (G0S2) is an important negative regulator of the rate-limiting lipolytic enzyme adipose triglyceride lipase-mediated lipolysis. It has been reveale...

    Authors: Naiqian Zhao, Li Wang and Na Guo
    Citation: Lipids in Health and Disease 2016 15:36
    Content type: Research Published on:

  19. As the major storage site for triglycerides and free cholesterol, adipose tissue plays a central role in energy metabolism. ApoA-I is the main constituent of HDL and plays an important role in removal of exces...

    Authors: Shuai Wang, Dao-quan Peng and Yuhong Yi
    Citation: Lipids in Health and Disease 2016 15:35
    Content type: Review Published on:

  20. Apolipoprotein E (apoE) induces the uptake of vitamin K-rich lipoproteins by the liver, which likely affects inter-individual variation of warfarin dosing requirements. Associations between APOE polymorphisms and...

    Authors: Rui Liu, Kui Zhang, Zhi-zhong Gong, Xin-miao Shi, Qian Zhang, Xiao-dong Pan and Ran Dong
    Citation: Lipids in Health and Disease 2016 15:34
    Content type: Research Published on:

  21. Atherosclerosis is a common pathological basis of cardiovascular disease. Adiponectin (APN) has been shown to have an anti-atherosclerosis effect, and the underlying mechanisms, however, are largely unknown. N...

    Authors: Xuemei Wang, Qingjie Chen, Hongwei Pu, Qin Wei, Mingjun Duan, Chun Zhang, Tao Jiang, Xi Shou, Jianlong Zhang and Yining Yang
    Citation: Lipids in Health and Disease 2016 15:33
    Content type: Research Published on:

  22. A plant-based strategy to improve long-chain (LC) omega (n)-3 PUFA supply in humans involves dietary supplementation with oils containing α-linolenic acid (ALA) alone or in combination with stearidonic acid (S...

    Authors: Katrin Kuhnt, Stefanie Weiß, Michael Kiehntopf and Gerhard Jahreis
    Citation: Lipids in Health and Disease 2016 15:32
    Content type: Research Published on:

  23. N-3 and N-6 polyunsaturated fatty acids are widely used in reproduction, yet few studies have addressed the effects of dietary n-6/n-3 ratios on boar reproduction. The present study aimed to determine the effe...

    Authors: Yan Lin, Xu Cheng, Jiude Mao, De Wu, Bo Ren, Sheng-Yu Xu, Zheng-Feng Fang, Lian-Qiang Che, Cai-Mei Wu and Jian Li
    Citation: Lipids in Health and Disease 2016 15:31
    Content type: Research Published on:

  24. Total polar compounds (TPC) formed during successive frying have the negative healthy effects. However, little researches focused on the cytotoxicity of different parts of TPC. The present study was carried ou...

    Authors: Jinwei Li, Xiaodan Li, Wenci Cai and Yuanfa Liu
    Citation: Lipids in Health and Disease 2016 15:30
    Content type: Short report Published on:

  25. The FTO gene has recently become one of the most extensively investigated genes associated with body mass and has been shown to play a role in cardiovascular diseases as well. The aim of the current study was to ...

    Authors: Saleem Ullah Shahid, Shabana, Abdul Rehman and Shahida Hasnain
    Citation: Lipids in Health and Disease 2016 15:29
    Content type: Research Published on:

  26. The effect of alirocumab on potentially atherogenic lipoprotein subfractions was assessed in a post hoc analysis using the vertical auto profile (VAP) method.

    Authors: Peter P. Toth, Sara C. Hamon, Steven R. Jones, Seth S. Martin, Parag H. Joshi, Krishnaji R. Kulkarni, Poulabi Banerjee, Corinne Hanotin, Eli M. Roth and James M. McKenney
    Citation: Lipids in Health and Disease 2016 15:28
    Content type: Research Published on:

  27. The incidence of non-alcoholic fatty liver disease (NAFLD), commonly associated with obesity and metabolic syndrome, is increasing worldwide. However, the specific mechanisms that mediate the progression from ...

    Authors: Jiali Liu, Lina Han, Leilei Zhu and Yerong Yu
    Citation: Lipids in Health and Disease 2016 15:27
    Content type: Research Published on:

  28. ANGPTL8 (betatrophin) has been recently identified as a regulator of lipid metabolism through its interaction with ANGPTL3. A sequence variant in ANGPTL8 has been shown to associate with lower level of Low Den...

    Authors: Mohamed Abu-Farha, Motasem Melhem, Jehad Abubaker, Kazem Behbehani, Osama Alsmadi and Naser Elkum
    Citation: Lipids in Health and Disease 2016 15:26
    Content type: Research Published on:

  29. A body of translational evidence has implicated dietary deficiency in long-chain omega-3 (LCn-3) fatty acids, including eicosapenaenoic acid (EPA) and docosahexaenoic acid (DHA), in the pathophysiology and potent...

    Authors: Erik Messamore and Robert K. McNamara
    Citation: Lipids in Health and Disease 2016 15:25
    Content type: Review Published on:

  30. Hepatic mitochondrial dysfunction plays an important role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Methyl donor supplementation has been shown to alleviate NAFLD, connecting the condit...

    Authors: Rolf K. Berge, Bodil Bjørndal, Elin Strand, Pavol Bohov, Carine Lindquist, Jan Erik Nordrehaug, Asbjørn Svardal, Jon Skorve and Ottar Nygård
    Citation: Lipids in Health and Disease 2016 15:24
    Content type: Research Published on:

  31. Emerging evidence suggested phytosterol esters (PE) exhibited an advantage over naturally occurring phytosterols in reducing atherosclerosis risk factors due to improved fat solubility and compatibility. Howev...

    Authors: Qianchun Deng, Xiao Yu, Jiqu Xu, Xiuying Kou, Mingming Zheng, Fenghong Huang, Qingde Huang and Lan Wang
    Citation: Lipids in Health and Disease 2016 15:23
    Content type: Research Published on:

  32. The prevalence of chronic kidney disease is rising continuously. Cardiovascular disease is among leading causes of death and premature mortality of patients with chronic kidney disease. Even the earliest stage...

    Authors: Anna Gluba-Brzózka, Marta Michalska-Kasiczak, Beata Franczyk, Marek Nocuń, Peter P. Toth, Maciej Banach and Jacek Rysz
    Citation: Lipids in Health and Disease 2016 15:22
    Content type: Research Published on:

    The Erratum to this article has been published in Lipids in Health and Disease 2016 15:62

  33. Circumstantial evidence suggests that conjugated linoleic acid (CLA) beneficially modulates immune function in allergic subjects. C9,t11-CLA, naturally occurring in ruminant fats, is suggested to be the effective...

    Authors: Anke Jaudszus, Jochen G. Mainz, Sylvia Pittag, Sabine Dornaus, Christian Dopfer, Alexander Roth and Gerhard Jahreis
    Citation: Lipids in Health and Disease 2016 15:21
    Content type: Research Published on:

  34. Intake of fish oil rich in n-3 polyunsaturated fatty acids (PUFAs) is believed to be beneficial against development of non-alcoholic fatty liver disease (NAFLD). However, the underlying mechanisms remain uncle...

    Authors: Fahu Yuan, Hualin Wang, Yu Tian, Qi Li, Lei He, Na Li and Zhiguo Liu
    Citation: Lipids in Health and Disease 2016 15:20
    Content type: Research Published on:

  35. The 3D structure and functions of ENPP4, a protein expressed on the surface of Bacillus Calmette–Guerin (BCG)-activated macrophages, are unknown. In this study, we analyzed the 3D structure of ENPP4 and determ...

    Authors: Dongmei Yan, Weiwei Han, Zehua Dong, Qihui Liu, Zheng Jin, Dong Chu, Yuan Tian, Jinpei Zhang, Dandan Song, Dunhuang Wang and Xun Zhu
    Citation: Lipids in Health and Disease 2016 15:19
    Content type: Research Published on:

  36. Plasma levels of high-density lipoprotein cholesterol (HDL-C) have been associated to cardiovascular disease. The high heritability of HDL-C plasma levels has been an incentive for several genome wide associat...

    Authors: Marco Cavalli, Gang Pan, Helena Nord and Claes Wadelius
    Citation: Lipids in Health and Disease 2016 15:18
    Content type: Short report Published on:

  38. The aims of this study were to evaluate the effect of poloxamer 407 administration on atherogenic serum lipoprotein fractions and subfractions associated with cholesterol, triglycerides and phospholipids, as well...

    Authors: Tatyana A. Korolenko, Thomas P. Johnston, Fedor V. Tuzikov, Natalia A. Tuzikova, Alexandr B. Pupyshev, Victor K. Spiridonov, Natalya V. Goncharova, Igor V. Maiborodin and Natalia A. Zhukova
    Citation: Lipids in Health and Disease 2016 15:16
    Content type: Research Published on:

  40. Endothelial dysfunction is considered an early step of atherosclerotic vascular disease. Asymmetric dimethylarginine (ADMA), the main endogenous inhibitor of nitric oxide synthase (NOS), plays a critical role ...

    Authors: Mauro Sergio Martins Marrocos, Andrei Alkmin Teixeira, Beata Marie Quinto, Silmara de Melo Carmona, Mariana Kuniyoshi, Cassio Jose Rodrigues, Maria Aparecida Dalboni, Silvia Manfredi, Maria Eugênia Canziani and Marcelo Costa Batista
    Citation: Lipids in Health and Disease 2016 15:14
    Content type: Research Published on:

  41. Sphingolipids, a group of lipids containing the sphingoid base, have both structural and biological functions in human epidermis. Ceramides, as a part of extracellular lipids in the stratum corneum, are import...

    Authors: Sonia Borodzicz, Lidia Rudnicka, Dagmara Mirowska-Guzel and Agnieszka Cudnoch-Jedrzejewska
    Citation: Lipids in Health and Disease 2016 15:13
    Content type: Review Published on:

  42. The severe forms of hypertriglyceridemia are usually caused by genetic defects. In this study, we described a Chinese female with severe hypertriglyceridemia caused by a novel homozygous mutation in the APOC2 ...

    Authors: Jingjing Jiang, Yuhui Wang, Yan Ling, Abudurexiti Kayoumu, George Liu and Xin Gao
    Citation: Lipids in Health and Disease 2016 15:12
    Content type: Research Published on:

    The Erratum to this article has been published in Lipids in Health and Disease 2016 15:42

  43. The inflammatory process seen in inflammatory bowel disease (IBD) is due to excess production of pro-inflammatory cytokines interleukin-1 (IL-1), IL-6, tumor necrosis factor-α (TNF-α), interferons (IFNs), macr...

    Authors: Undurti N. Das
    Citation: Lipids in Health and Disease 2016 15:11
    Content type: Hypothesis Published on:

  44. Impaired glucose regulation (IGR) and hyperlipidemia (HL) are associated with an increased risk of developing a cardiovascular disease. Hyperlipidemic patients were shown to bear a greater risk for an increase...

    Authors: Michael Leutner, Christian Göbl, Alice Wielandner, Eleonora Howorka, Marlies Prünner, Latife Bozkurt, Oliver Schlager, Silvia Charwat-Resl and Alexandra Kautzky-Willer
    Citation: Lipids in Health and Disease 2016 15:10
    Content type: Research Published on:

  45. Cholesteryl ester transfer protein (CETP) is a plasma protein that mediates the exchange of triglycerides for esterified cholesterol between HDL and apoB-lipoproteins. Previous studies suggest that CETP may mo...

    Authors: Helena F. Raposo, Emerielle C. Vanzela, Jairo A. Berti and Helena C F Oliveira
    Citation: Lipids in Health and Disease 2016 15:9
    Content type: Research Published on:

  46. The Neurocan-cartilage intermediate layer protein 2 (NCAN-CILP2) region forms a tight linkage disequilibrium (LD) block and is associated with plasma lipid levels and non-alcoholic fatty liver disease (NAFLD) in ...

    Authors: Supichaya Boonvisut, Kazuhiro Nakayama, Saho Makishima, Kazuhisa Watanabe, Hiroshi Miyashita, Munkhtulga Lkhagvasuren, Yasuo Kagawa and Sadahiko Iwamoto
    Citation: Lipids in Health and Disease 2016 15:8
    Content type: Research Published on:

  47. Several single nucleotide polymorphisms (SNPs) in lipid transport genes have been shown to be associated with premature coronary artery disease (PCAD). The scavenger receptor BI (SCARB1) is a key component of ...

    Authors: Hamidreza Goodarzynejad, Mohammadali Boroumand, Mehrdad Behmanesh, Shayan Ziaee and Arash Jalali
    Citation: Lipids in Health and Disease 2016 15:7
    Content type: Research Published on:

  48. Coronary Heart Disease (CHD) is one of the leading causes of death in the world with a projected global 82 million DALYs by 2020. Genetic and environmental factors contribute to CHD development. Here, the auth...

    Authors: Joseph Sam Kanu, Yulu Gu, Sun Zhi, Mingxi Yu, Yuping Lu, Yetong Cong, Yunkai Liu, Yong Li, Yaqin Yu, Yi Cheng and Yawen Liu
    Citation: Lipids in Health and Disease 2016 15:6
    Content type: Research Published on:

  49. Fatty acid-binding protein 4 (FABP4/A-FABP/aP2) mainly expressed in adipocytes is secreted and acts as an adipokine. Increased circulating FABP4 level is associated with obesity, insulin resistance and atheros...

    Authors: Masato Furuhashi, Shinya Hiramitsu, Tomohiro Mita, Akina Omori, Takahiro Fuseya, Shutaro Ishimura, Yuki Watanabe, Kyoko Hoshina, Megumi Matsumoto, Marenao Tanaka, Norihito Moniwa, Hideaki Yoshida, Junnichi Ishii and Tetsuji Miura
    Citation: Lipids in Health and Disease 2016 15:5
    Content type: Research Published on:

  50. Diet and obesity are recognized in the scientific literature as important risk factors for cancer development and progression. Hypercholesterolemia facilitates lymphoma lymphoblastic cell growth and in time tu...

    Authors: Michela Codini, Samuela Cataldi, Andrea Lazzarini, Anna Tasegian, Maria Rachele Ceccarini, Alessandro Floridi, Remo Lazzarini, Francesco Saverio Ambesi-Impiombato, Francesco Curcio, Tommaso Beccari and Elisabetta Albi
    Citation: Lipids in Health and Disease 2016 15:4
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X