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  1. The biodiversity of the marine environment and the associated chemical diversity constitute a practically unlimited source of new active substances in the field of the development of bioactive products. In our...

    Authors: Yosra Ayed, Manel Bousabbeh, Hazem Ben Mabrouk, Maram Morjen, Naziha Marrakchi and Hassen Bacha
    Citation: Lipids in Health and Disease 2012 11:84
  2. Excess peroxisome proliferator-activated receptor (PPAR) stimulation has been associated with detrimental health effects including impaired myocardial function. Recently, supplementation with n-3 polyunsaturat...

    Authors: Elin Strand, Bodil Bjorndal, Ottar Nygard, Lena Burri, Christ Berge, Pavol Bohov, Bjørn J Christensen, Kjetil Berge, Hege Wergedahl, Asgaut Viste and Rolf K Berge
    Citation: Lipids in Health and Disease 2012 11:82
  3. Rose-scented geranium (Pelargonium graveolens L’Hér.), which is used in traditional Tunisian folk medicine for the treatment of hyperglycaemia, is widely known as one of the medicinal herbs with the highest antio...

    Authors: Maher Boukhris, Mohamed Bouaziz, Ines Feki, Hedya Jemai, Abdelfattah El Feki and Sami Sayadi
    Citation: Lipids in Health and Disease 2012 11:81
  4. A sedentary lifestyle predisposes to cardiometabolic diseases. Lifestyle changes such as increased physical activity improve a range of cardiometabolic risk factors. The objective of this study was to examine ...

    Authors: Per Sjögren, Justo Sierra-Johnson, Lena V Kallings, Tommy Cederholm, Maria Kolak, Mats Halldin, Kerstin Brismar, Ulf de Faire, Mai-Lis Hellénius and Rachel M Fisher
    Citation: Lipids in Health and Disease 2012 11:80
  5. There is a relationship among hypercholesterolemia, oxidative stress and inflammation in the atherogenesis. Thus, the objective of the present study was to assess paraoxonase (PON1), superoxide dismutase (SOD)...

    Authors: Paula Rossini Augusti, Amanda Roggia Ruviaro, Andréia Quatrin, Sabrina Somacal, Greicy Michelle Marafiga Conterato, Juliana Tanara Vicentini, Marta Medeiros Frescura Duarte and Tatiana Emanuelli
    Citation: Lipids in Health and Disease 2012 11:79
  6. The main purpose of this research was to investigate the alterations in the aerobic capacity and appearance of metabolic alterations in Wistar rats fed on fructose-rich diet. We separated twenty-eight rats int...

    Authors: José Diego Botezelli, Lucieli Teresa Cambri, Ana Carolina Ghezzi, Rodrigo Augusto Dalia, Fabrício Azevedo Voltarelli and Maria Alice Rostom de Mello
    Citation: Lipids in Health and Disease 2012 11:78
  7. Cardiovascular disease (CVD) is the number one cause of mortality worldwide and a low high-density lipoprotein cholesterol (HDL-C) level is an important marker of CVD risk. Garlic (Allium sativum) has been widely...

    Authors: Seohyun Lee, Hyunjin Joo, Chong-Tai Kim, In-Hwan Kim and Yangha Kim
    Citation: Lipids in Health and Disease 2012 11:77
  8. Altered immune function during ageing results in increased production of nitric oxide (NO) and other inflammatory mediators. Recently, we have reported that NO production was inhibited by naturally-occurring p...

    Authors: Asaf A Qureshi, Xiu Qin Guan, Julia C Reis, Christopher J Papasian, Sandra Jabre, David C Morrison and Nilofer Qureshi
    Citation: Lipids in Health and Disease 2012 11:76
  9. Resynthesis of triglycerides in enterocytes of the small intestine plays a critical role in the absorption of dietary fat. Acyl-CoA:monoacylglycerol acyltransferase-2 (MGAT2) is highly expressed in the small i...

    Authors: Takuma Tsuchida, Sayaka Fukuda, Hisanori Aoyama, Nobuhiko Taniuchi, Tomomi Ishihara, Noriko Ohashi, Hiroko Sato, Koji Wakimoto, Masaharu Shiotani and Akira Oku
    Citation: Lipids in Health and Disease 2012 11:75
  10. We describe a system for the automated diagnosis of diabetic retinopathy and glaucoma using fundus and optical coherence tomography (OCT) images. Automatic screening will help the doctors to quickly identify t...

    Authors: Arulmozhivarman Pachiyappan, Undurti N Das, Tatavarti VSP Murthy and Rao Tatavarti
    Citation: Lipids in Health and Disease 2012 11:73
  11. The present work aims at preparing aqueous suspension of Solid lipid Nanoparticles containing Chitosan (CT) which is a biopolymer that exhibits a number of interesting properties which include controlled drug ...

    Authors: Rahul Nair, Ashok CK Kumar, Vishnu K Priya, Chakrapani M Yadav and Prasanna Y Raju
    Citation: Lipids in Health and Disease 2012 11:72
  12. The health benefits of omega-3 and omega-6 polyunsaturated fatty acids (PUFA) are generally recognized. Unfortunately, in most Mediterranean countries, the recommended daily intake of these compounds is rarely...

    Authors: Imen Fendri, Lamia Khannous, Zouhir Mallek, Al Ibrahim Traore, Néji Gharsallah and Radhouane Gdoura
    Citation: Lipids in Health and Disease 2012 11:71
  13. Bioactivities of Docosahexaenoic acid (DHA) and Eicosapentaenoic acid (EPA) depend on their chemical forms. The present study was to investigate short term effects of triglyceride (TG), ethyl ester (EE), free ...

    Authors: Xiao Tang, Zhao-Jie Li, Jie Xu, Yong Xue, Jin-Zhang Li, Jing-Feng Wang, Teruyoshi Yanagita, Chang-Hu Xue and Yu-Ming Wang
    Citation: Lipids in Health and Disease 2012 11:70
  14. Retinoic acids regulate the reverse cholesterol transport by inducing the ATP binding cassette transporter A1 (ABCA1) dependent cholesterol efflux in macrophages, neuronal as well as intestine cells. In the pr...

    Authors: Hong Jiang, Yunden Badralmaa, Jun Yang, Richard Lempicki, Allison Hazen and Ven Natarajan
    Citation: Lipids in Health and Disease 2012 11:69
  15. The effects of exposure to a 50 Hz electric field (EF) on plasma level of triacylglycerol, free fatty acids, total cholesterol and phospholipid and mRNA expression level of diacylglycerol acyltransferase (DGAT...

    Authors: Takuya Hori, Shinji Harakawa, Shirley M Herbas, Yoshiko Y Ueta, Noboru Inoue and Hiroshi Suzuki
    Citation: Lipids in Health and Disease 2012 11:68
  16. Obesity and type 2 diabetes mellitus (DM) have grown in prevalence around the world, and recently, related diseases have been considered epidemic. Given the high cost of treatment of obesity/DM-associated dise...

    Authors: Gabriela TD Sousa, Fábio S Lira, José C Rosa, Erick P de Oliveira, Lila M Oyama, Ronaldo V Santos and Gustavo D Pimentel
    Citation: Lipids in Health and Disease 2012 11:67
  17. Hepatic gluconeogenesis tightly controls blood glucose levels in healthy individuals, yet disorders of fatty acids (FAs) oxidation are characterized by hypoglycemia. We studied the ability of free-FAs to direc...

    Authors: Noga Budick-Harmelin, Sarit Anavi, Zecharia Madar and Oren Tirosh
    Citation: Lipids in Health and Disease 2012 11:66
  18. The aim was to investigate new markers for type 2 diabetes (T2DM) dyslipidemia related with LDL and HDL metabolism. Removal from plasma of free and esterified cholesterol transported in LDL and the transfer of...

    Authors: Carolina P Oliveira, Raul C Maranhão, Marina P Bertato, Bernardo L Wajchenberg and Antonio C Lerario
    Citation: Lipids in Health and Disease 2012 11:65
  19. Many of the metabolic effects of exercise are due to the most recent exercise session. With recent advances in nuclear magnetic resonance spectroscopy (NMRS), it is possible to gain insight about which lipopro...

    Authors: Michael Harrison, Niall M Moyna, Theodore W Zderic, Donal J O’Gorman, Noel McCaffrey, Brian P Carson and Marc T Hamilton
    Citation: Lipids in Health and Disease 2012 11:64
  20. Conjugated linoleic acids (CLA) are in focus of dairy cattle research because of its milk fat reducing effects. Little is known about the impact of CLA on immune function in dairy cows. Therefore, in the prese...

    Authors: Lydia Renner, Julia Pappritz, Ronny Kramer, Susanne Kersten, Gerhard Jahreis and Sven Dänicke
    Citation: Lipids in Health and Disease 2012 11:63
  21. One of the important proteins involved in lipid metabolism is the ATP-binding cassette transporter A1 (ABCA1) encoding by ABCA1 gene. In this study we evaluated the single nucleotide polymorphisms (SNPs) of ABCA1...

    Authors: Vana Kolovou, Apostolia Marvaki, Agathi Karakosta, Georgios Vasilopoulos, Antonia Kalogiani, Sophie Mavrogeni, Dimitrios Degiannis, Christina Marvaki and Genovefa Kolovou
    Citation: Lipids in Health and Disease 2012 11:62
  22. Niemann-pick C1-like 1 (NPC1L1) is a key protein for intestinal cholesterol transportation. Common single nucleotide polymorphisms (SNPs) in the NPC1L1 gene have been associated with cholesterol absorption and...

    Authors: Lin Miao, Rui-Xing Yin, Xi-Jiang Hu, Dong-Feng Wu, Xiao-Li Cao, Qing Li, Ting-Ting Yan, Lynn Htet Htet Aung, Jin-Zhen Wu and Wei-Xiong Lin
    Citation: Lipids in Health and Disease 2012 11:61
  23. Polyunsaturated fatty acids (PUFA) have diverse biological effects, from promoting inflammation to preventing cancer and heart disease. Growing evidence suggests that individual PUFA may have independent effec...

    Authors: Jessica Monteiro, Feng-Jun Li, Mira MacLennan, Alexandra Rabalski, Mohammed H Moghadasian, Manabu T Nakamura and David WL Ma
    Citation: Lipids in Health and Disease 2012 11:60
  24. The lipid-lowering treatment goal attainment rate is lower for women than for men among Chinese patients, but the reasons for this disparity have not been fully explored yet.

    Authors: Rui Zhang, Liancheng Zhao, Lirong Liang, Gaoqiang Xie and Yangfeng Wu
    Citation: Lipids in Health and Disease 2012 11:59
  25. Various therapeutic effects of fenugreek (Trigonella foenum-graecum L.) on metabolic disorders have been reported. However, the bitterness of fenugreek makes it hard for humans to eat sufficient doses of it for a...

    Authors: Etsuko Muraki, Hiroshige Chiba, Keiko Taketani, Shohei Hoshino, Nobuaki Tsuge, Nobuyo Tsunoda and Keizo Kasono
    Citation: Lipids in Health and Disease 2012 11:58
  26. This study was designed to investigate the effect of alpha lipoic acid (ALA) and alpha tocopherol acetate (ATA) on the antioxidant potential, lipid stability and the quality of the broiler breast meat and meat...

    Authors: Muhammad Sohaib, Faqir Muhammad Anjum, Muhammad Issa Khan, Muhammad Sajid Arshad and Muhammad Shahid
    Citation: Lipids in Health and Disease 2012 11:57
  27. Resveratrol (RSV), a naturally occurring polyphenolic stilbenoid, is known to possess potent anti-atherogenic properties; however, the effect of RSV on hypercholesterolemia is not fully understood. We hypothes...

    Authors: Qiong Chen, Ermao Wang, Liping Ma and Pei Zhai
    Citation: Lipids in Health and Disease 2012 11:56
  28. Hyperlipidemia plays a crucial role in the development and progression of coronary artery disease (CAD). Recent studies have identified that microRNAs (miRNAs) are important regulators of lipid metabolism, but...

    Authors: Wei Gao, Hui-Wei He, Ze-Mu Wang, Huan Zhao, Xiao-Qing Lian, Yong-Sheng Wang, Jun Zhu, Jian-Jun Yan, Ding-Guo Zhang, Zhi-Jian Yang and Lian-Sheng Wang
    Citation: Lipids in Health and Disease 2012 11:55
  29. A higher prevalence of coronary heart disease (CHD) in people with diabetes. We investigated the high-density lipoprotein (HDL) subclass profiles and alterations of particle size in CHD patients with diabetes ...

    Authors: Li Tian, Shiyin Long, Chuanwei Li, Yinghui Liu, Yucheng Chen, Zhi Zeng and Mingde Fu
    Citation: Lipids in Health and Disease 2012 11:54
  30. Serum β-cryptoxanthin levels are lower in overweight subjects than in normal subjects. Abnormalities of adipocytokine profiles in obesity subjects have been reported. There are several reports that serum β-cry...

    Authors: Masako Iwamoto, Katsumi Imai, Hideaki Ohta, Bungo Shirouchi and Masao Sato
    Citation: Lipids in Health and Disease 2012 11:52
  31. Bai Ku Yao is a special subgroup of the Yao minority in China. The present study was undertaken to detect the association of rs5888 single nucleotide polymorphism (SNP) in the scavenger receptor class B type 1...

    Authors: Dong-Feng Wu, Rui-Xing Yin, Xi-Jiang Hu, Lynn Htet Htet Aung, Xiao-Li Cao, Lin Miao, Qing Li, Ting-Ting Yan, Jin-Zhen Wu and Shang-Ling Pan
    Citation: Lipids in Health and Disease 2012 11:50
  32. Oilseed samples from four Acacia species ( A. cyclops, A. ligulata, A. salicina and A. cyanophylla) were analyzed in order to evaluate the potential nutritional value of their unexploited seeds.

    Authors: Nizar Nasri, Walid Elfalleh, Nizar Tlili, Hédia Hannachi, Saida Triki and Abdelhamid Khaldi
    Citation: Lipids in Health and Disease 2012 11:49
  33. Nonalcoholic fatty liver disease (NAFLD) is a prevalent chronic liver disease in industrialized countries. The present study was undertaken to explore the preventive effect of dietary sea cucumber cerebroside ...

    Authors: Bei Zhang, Changhu Xue, Xiaoqian Hu, Jie Xu, Zhaojie Li, Jingfeng Wang, Teruyoshi Yanagita, Yong Xue and Yuming Wang
    Citation: Lipids in Health and Disease 2012 11:48
  34. Dyslipidemia is common in chronic hemodialysis patients and its underlying mechanism is complex. Hemodialysis causes an imbalance between antioxidants and production of reactive oxygen species, which induces t...

    Authors: Agnieszka Makówka, Przemysław Dryja, Grażyna Chwatko, Edward Bald and Michał Nowicki
    Citation: Lipids in Health and Disease 2012 11:47
  35. The association of ATP binding cassette transporter G8 gene (ABCG8) rs4148217 single nucleotide polymorphism (SNP) and serum lipid profiles is still controversial in diverse racial/ethnic groups. Mulao nationalit...

    Authors: Qing Li, Xian-Liang Wei and Rui-Xing Yin
    Citation: Lipids in Health and Disease 2012 11:46
  36. Fuzheng Huayu recipe (FZHY), a compound of Chinese herbal medicine, was reported to improve liver function and fibrosis in patients with hepatitis B virus infection. However, its effect on nutritional fibrosin...

    Authors: Yan-Hong Jia, Rong-Qi Wang, Hong-Mei Mi, Ling-Bo Kong, Wei-Guang Ren, Wen-Cong Li, Su-Xian Zhao, Yu-Guo Zhang, Wen-Juan Wu, Yue-Min Nan and Jun Yu
    Citation: Lipids in Health and Disease 2012 11:45
  37. Serum lipid profiles may be influenced by thyroid function, but the detailed mechanism remains unclear. Increasing evidence suggests that thyrotropin (TSH) may exert extra-thyroidal effects. The goal of this s...

    Authors: Xing Wanjia, Wang Chenggang, Wang Aihong, Yang Xiaomei, Zhao Jiajun, Yu Chunxiao, Xu Jin, Hou Yinglong and Gao Ling
    Citation: Lipids in Health and Disease 2012 11:44
  38. n-3 fatty acids and lifestyle also are closely related to risk of CVD. Most Koreans have higher fish consumption than people of Western populations. However, little is known about the recommended value of omeg...

    Authors: Young Joo Kim, Dong Wook Jeong, Jeong Gyu Lee, Han Cheol Lee, Sang Yeoup Lee, Yun Jin Kim, Yu Hyeon Yi, Yong Soon Park, Young Hye Cho, Mi Jin Bae and Eun Jung Choi
    Citation: Lipids in Health and Disease 2012 11:43
  39. Observational studies have shown that low serum levels of vitamin D have been associated with an atherogenic lipid profile. However, the intervention studies gave divergent results. We conducted a meta-analysi...

    Authors: Hao Wang, Ning Xia, Yang Yang and Dao-Quan Peng
    Citation: Lipids in Health and Disease 2012 11:42
  40. An increased interest is given to the impact of high fat diet on health worldwide. Abnormalities in lipid metabolism induced by high cholesterol diet (HCD) were reported to exacerbate renal diseases via oxidat...

    Authors: Salim Salih Al-Rejaie, Hatem Mustafa Abuohashish, Osama Abdelrahman Alkhamees, Abdulaziz Mohammed Aleisa and Abdulaziz S Alroujayee
    Citation: Lipids in Health and Disease 2012 11:41
  41. In a bid to reduce the morbidity and mortality associated with coronary artery disease, statin therapy has become a cornerstone treatment for patients with dyslipideamia. Statins, or HMG-CoA reductase inhibito...

    Authors: Stuart J Semple
    Citation: Lipids in Health and Disease 2012 11:40
  42. Cholesterol homeostasis dysfunction has been reported to have role in the pathogenesis of Alzheimer disease (AD). Therefore, changes in cholesterol metabolism in blood components may help to develop new potent...

    Authors: Antonella Mandas, Claudia Abete, Paolo Francesco Putzu, Paolo la Colla, Sandra Dessì and Alessandra Pani
    Citation: Lipids in Health and Disease 2012 11:39
  43. In folklore, some people take the decoction of Calyx seu Fructus Physalis (CSFP) for lowering blood lipids. The present study is designed to evaluate the lipid-lowering activities of CSFP, and search for its phar...

    Authors: Yihui Yang, Xianmei Piao, Mingyu Zhang, Xiaodan Wang, Bing Xu, Jiuxin Zhu, Zhiwei Fang, Yunlong Hou, Yanjie Lu and Baofeng Yang
    Citation: Lipids in Health and Disease 2012 11:38
  44. Several parameters are associated with high bone mineral density (BMD), such as overweight, black background, intense physical activity (PA), greater calcium intake and some medications. The objectives are to ...

    Authors: Karin S Sarkis, Lígia A Martini, Vera L Szejnfeld and Marcelo M Pinheiro
    Citation: Lipids in Health and Disease 2012 11:37
  45. Fatty acid-induced insulin resistance and impaired glucose uptake activity in muscle cells are fundamental events in the development of type 2 diabetes and hyperglycemia. There is an increasing demand for comp...

    Authors: Keisuke Sawada, Kyuichi Kawabata, Takatoshi Yamashita, Kengo Kawasaki, Norio Yamamoto and Hitoshi Ashida
    Citation: Lipids in Health and Disease 2012 11:36
  46. Increasing consumer demand for healthier food products has led to the development of governmental policies regarding health claims in many developed countries. In this context, contamination of poultry by food...

    Authors: Zouhir Mallek, Imen Fendri, Lamia Khannous, Amal Ben Hassena, Al Ibrahim Traore, Mohamed-Ali Ayadi and Radhouane Gdoura
    Citation: Lipids in Health and Disease 2012 11:35
  47. Fibroblast growth factor 21 (FGF21), whose expression is induced by peroxisome proliferator-activated receptor α (PPARα), has been recently identified as a novel metabolic regulator which plays a crucial role ...

    Authors: Juliane Varady, Robert Ringseis and Klaus Eder
    Citation: Lipids in Health and Disease 2012 11:34

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