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  1. There is increasing interest in non-pharmacological control of cholesterol and triglyceride levels in the plasma and diet-drug association represent an important area of studies. The objective of this study wa...

    Authors: Ederlan S Ferreira, Maraiza A Silva, Aureluce Demonte and Valdir A Neves
    Citation: Lipids in Health and Disease 2012 11:11
    Content type: Research Published on:

  2. Ischemia/reperfusion leads to inflammation and oxidative stress which damages membrane highly polyunsaturated fatty acids (HPUFAs) and eventually induces neuronal death. This study evaluates the effect of the ...

    Authors: Marina Quartu, Maria P Serra, Marianna Boi, Giuliano Pillolla, Tiziana Melis, Laura Poddighe, Marina Del Fiacco, Danilo Falconieri, Gianfranca Carta, Elisabetta Murru, Lina Cordeddu, Antonio Piras, Maria Collu and Sebastiano Banni
    Citation: Lipids in Health and Disease 2012 11:8
    Content type: Research Published on:

  3. The impact of leucine supplementation and resistance exercise (RE) on plasma lipid profile was evaluated in adult rats treated with dexamethasone, an experimental model of dyslipidemia. Total cholesterol did n...

    Authors: Humberto Nicastro, Claudia R da Luz, Daniela F S Chaves, William das Neves, Kerolyn S Valente and Antonio H Lancha Jr
    Citation: Lipids in Health and Disease 2012 11:7
    Content type: Short report Published on:

  5. Hemorrhagic shock followed by resuscitation stimulates an inflammatory response. This study tests the hypothesis that treatment with fish oil will attenuate inflammatory responses and stabilize hemodynamics.

    Authors: Yang Li, Xinying Wang, Ning Li and Jieshou Li
    Citation: Lipids in Health and Disease 2012 11:5
    Content type: Research Published on:

  6. We analyzed the causal relationship between LDL susceptibility to oxidation and the development of new carotid artery atherosclerosis over a period of 5 years. We previously described the determinants related ...

    Authors: Toshinari Aoki, Tsueko Abe, Eiji Yamada, Takayuki Matsuto and Masahiko Okada
    Citation: Lipids in Health and Disease 2012 11:4
    Content type: Research Published on:

  7. Beneficial effects of dietary phospholipids (PLs) have been mentioned since the early 1900's in relation to different illnesses and symptoms, e.g. coronary heart disease, inflammation or cancer. This article g...

    Authors: Daniela Küllenberg, Lenka A Taylor, Michael Schneider and Ulrich Massing
    Citation: Lipids in Health and Disease 2012 11:3
    Content type: Review Published on:

  8. Studies using laboratory animals under what are considered to be "standard" conditions normally offer unrestricted amounts of food to the animals, which can lead to metabolic disorders. Moreover, standard diet...

    Authors: Leandro P Moura, Gabriella A Figueredo, Natália O Bertolini, Marilia Ceccato, Jessica R Pereira, Amanda Christine S Sponton and Maria Alice R de Mello
    Citation: Lipids in Health and Disease 2012 11:2
    Content type: Research Published on:

  10. The association of rs16996148 single nucleotide polymorphism (SNP) in NCAN/CILP2/PBX4 and serum lipid levels is inconsistent. Furthermore, little is known about the association of rs16996148 SNP and serum lipid l...

    Authors: Ting-Ting Yan, Rui-Xing Yin, Qing Li, Ping Huang, Xiao-Na Zeng, Ke-Ke Huang, Lynn Htet Htet Aung, Dong-Feng Wu, Cheng-Wu Liu and Shang-Ling Pan
    Citation: Lipids in Health and Disease 2011 10:248
    Content type: Research Published on:

  11. Maternal nutrition in pregnancy has a crucial impact on the development of the fetus. Dietary trans fatty acids (t FA) are known to have adverse health effects, especially during pregnancy. However, the distribut...

    Authors: Uta Enke, Anke Jaudszus, Ekkehard Schleussner, Lydia Seyfarth, Gerhard Jahreis and Katrin Kuhnt
    Citation: Lipids in Health and Disease 2011 10:247
    Content type: Research Published on:

  12. Peroxisome proliferator activated receptor alpha (PPARα) regulates lipids metabolism and inhibits inflammatory response. However, the role of PPARα in alcoholic liver disease is largely unknown. We aim to eluc...

    Authors: Lingbo Kong, Weiguang Ren, Wencong Li, Suxian Zhao, Hongmei Mi, Rongqi Wang, Yuguo Zhang, Wenjuan Wu, Yuemin Nan and Jun Yu
    Citation: Lipids in Health and Disease 2011 10:246
    Content type: Research Published on:

  13. In the western world, heart failure (HF) is one of the most important causes of cardiovascular mortality. Supplement with n-3 polyunsaturated fatty acids (PUFA) has been shown to improve cardiac function in HF...

    Authors: Linn E Fosshaug, Rolf K Berge, Jan O Beitnes, Kjetil Berge, Hogne Vik, Pål Aukrust, Lars Gullestad, Leif E Vinge and Erik Øie
    Citation: Lipids in Health and Disease 2011 10:245
    Content type: Research Published on:

  14. ω-3 polyunsaturated fatty acids have been shown to play an important role in health. Enriched with ω-3 polyunsaturated fatty acids modulate expression of a number of genes with such broad functions as cell pro...

    Authors: Tao Guo, Xin F Liu, Xiang B Ding, Fei F Yang, Yong W Nie, Yu J An and Hong Guo
    Citation: Lipids in Health and Disease 2011 10:244
    Content type: Research Published on:

  15. The mevalonate pathway in human is responsible for the synthesis of cholesterol and other important biomolecules such as coenzyme Q, dolichols and isoprenoids. These molecules are required in the cell for func...

    Authors: Manish Rauthan and Marc Pilon
    Citation: Lipids in Health and Disease 2011 10:243
    Content type: Review Published on:

  16. The single nucleotide polymorphism (SNP) of peroxisome proliferator-activated receptor delta (PPARD) gene affects serum lipid profiles, but to what extent alcohol consumption interferes with this association rema...

    Authors: Xian-Liang Wei, Rui-Xing Yin, Lin Miao and Dong-Feng Wu
    Citation: Lipids in Health and Disease 2011 10:242
    Content type: Research Published on:

  17. The importance of arachidonic acid (ARA) among the elderly has recently gained increased attention. The effects of ARA supplementation in the elderly are not fully understood, although ARA is considered to be ...

    Authors: Saki Kakutani, Yoshiyuki Ishikura, Norifumi Tateishi, Chika Horikawa, Hisanori Tokuda, Masanori Kontani, Hiroshi Kawashima, Yutaka Sakakibara, Yoshinobu Kiso, Hiroshi Shibata and Ikuo Morita
    Citation: Lipids in Health and Disease 2011 10:241
    Content type: Research Published on:

  18. We previously reported that fenugreek (Trigonella foenum-graecum L.) improved diet-induced metabolic disorders in rats. The purpose of the present study was to examine the dose-dependent effects, safety and toler...

    Authors: Etsuko Muraki, Yukie Hayashi, Hiroshige Chiba, Nobuyo Tsunoda and Keizo Kasono
    Citation: Lipids in Health and Disease 2011 10:240
    Content type: Research Published on:

  19. Changes in immune function believed to contribute to a variety of age-related diseases have been associated with increased production of nitric oxide (NO). We have recently reported that proteasome inhibitors ...

    Authors: Asaf A Qureshi, Xiaoyu Tan, Julia C Reis, Mostafa Z Badr, Christopher J Papasian, David C Morrison and Nilofer Qureshi
    Citation: Lipids in Health and Disease 2011 10:239
    Content type: Research Published on:

  20. Brown adipose tissue (BAT) has thermogenic potential. For its activation, cold exposure is considered a critical factor though other determinants have also been reported. The purpose of this study was to asses...

    Authors: Yung-Cheng Huang, Tai-Been Chen, Chien-Chin Hsu, Shau-Hsuan Li, Pei-Wen Wang, Bi-Fang Lee, Ching-Yuan Kuo and Nan-Tsing Chiu
    Citation: Lipids in Health and Disease 2011 10:238
    Content type: Research Published on:

  21. The presence of smaller low-density lipoproteins (LDL) has been associated with atherosclerosis risk, and the insulin resistance (IR) underlying the metabolic syndrome (MetS). In addition, some research has su...

    Authors: Alexis C Frazier-Wood, Stephen Glasser, W Timothy Garvey, Edmond K Kabagambe, Ingrid B Borecki, Hemant K Tiwari, Michael Y Tsai, Paul N Hopkins, Jose M Ordovas and Donna K Arnett
    Citation: Lipids in Health and Disease 2011 10:237
    Content type: Research Published on:

  22. Thymoquinone (TQ), the major active component of the medicinal herb Nigella sativa Linn., has been described as a chemopreventive and chemotherapeutic compound.

    Authors: Gamal Badr, Mohamed Mohany and Faisal Abu-Tarboush
    Citation: Lipids in Health and Disease 2011 10:236
    Content type: Research Published on:

  23. Prolonged wound healing is a complication of diabetes that contributes to mortality. Impaired wound healing occurs as a consequence of excessive reactive oxygen species (ROS) production. Whey protein (WP) is a...

    Authors: Hossam Ebaid, Amir Salem, Abdalla Sayed and Ali Metwalli
    Citation: Lipids in Health and Disease 2011 10:235
    Content type: Research Published on:

  24. Nonalcoholic fatty liver disease (NAFLD) is one of the most frequent causes of abnormal liver function. Because fatty acids can damage biological membranes, fatty acid accumulation in the liver may be partiall...

    Authors: Xin Wang, Yuzhen Cao, Yunwei Fu, Guifang Guo and Xiuying Zhang
    Citation: Lipids in Health and Disease 2011 10:234
    Content type: Research Published on:

  25. Despite significant research efforts on cancer therapy, diagnostics and imaging, many challenges remain unsolved. There are many unknown details regarding the interaction of nanoparticles (NPs) and biological ...

    Authors: Mohamed Anwar K Abdelhalim
    Citation: Lipids in Health and Disease 2011 10:233
    Content type: Research Published on:

  26. The long-lasting and abundant blooming of Pelagia noctiluca in Tunisian coastal waters compromises both touristic and fishing activities and causes substantial economic losses. Determining their molecular mode of...

    Authors: Yosra Ayed, Manel Boussabbeh, Wiem Zakhama, Chayma Bouaziz, Salwa Abid and Hassen Bacha
    Citation: Lipids in Health and Disease 2011 10:232
    Content type: Research Published on:

  27. The kidneys are essential for the metabolism of vitamin A (retinol) and its transport proteins retinol-binding protein 4 (RBP4) and transthyretin. Little is known about changes in serum concentration after liv...

    Authors: Andrea Henze, Jens Raila, Caroline Kempf, Petra Reinke, Anett Sefrin, Uwe Querfeld and Florian J Schweigert
    Citation: Lipids in Health and Disease 2011 10:231
    Content type: Research Published on:

  28. The association of rs17321515 single nucleotide polymorphism (SNP) near TRIB1 gene and serum lipid profiles has never been studied in the Chinese population. Therefore, the present study was undertaken to dete...

    Authors: Lynn Htet Htet Aung, Rui-Xing Yin, Dong-Feng Wu, Qing Li, Ting-Ting Yan, Yi-Ming Wang, Hui Li, Dai-Xun Wei, Yuan-Lu Shi and De-Zhai Yang
    Citation: Lipids in Health and Disease 2011 10:230
    Content type: Research Published on:

  29. In obesity, phenotypic switches occur in macrophage populations such that the predominantly M2-polarised anti-inflammatory state seen in lean individuals changes to a predominantly M1-polarised pro-inflammator...

    Authors: Suleiman A Isa, José S Ruffino, Maninder Ahluwalia, Andrew W Thomas, Keith Morris and Richard Webb
    Citation: Lipids in Health and Disease 2011 10:229
    Content type: Research Published on:

  31. Docosahexaenoic acid (DHA) and DHA-containing ethanolamine plasmalogens (PlsEtn) are decreased in the brain, liver and the circulation in Alzheimer's disease. Decreased supply of plasmalogen precursors to the ...

    Authors: Paul L Wood, Tara Smith, Nina Lane, M Amin Khan, Greg Ehrmantraut and Dayan B Goodenowe
    Citation: Lipids in Health and Disease 2011 10:227
    Content type: Research Published on:

  32. diabetes is a serious health problem and a source of risk for numerous severe complications such as obesity and hypertension. Treatment of diabetes and its related diseases can be achieved by inhibiting key di...

    Authors: Khaled Hamden, Henda Keskes, Sahla Belhaj, Kais Mnafgui, Abdelfattah feki and Noureddine Allouche
    Citation: Lipids in Health and Disease 2011 10:226
    Content type: Research Published on:

  33. Endurance exercise is known to promote a substantial effect on the energy balance in rats and humans. However, little is known about the exact mechanisms for the appetite-suppressive effects of endurance exerc...

    Authors: Jiexiu Zhao, Ye Tian, Jincheng Xu, Dongsen Liu, Xiaofang Wang and Binxiu Zhao
    Citation: Lipids in Health and Disease 2011 10:225
    Content type: Research Published on:

  34. High-density lipoproteins (HDL) and their main apolipoprotein, apoA-I, exhibit anti-inflammatory properties. The development of peptides that mimic HDL apolipoproteins offers a promising strategy to reduce inf...

    Authors: Belinda A Di Bartolo, Laura Z Vanags, Joanne TM Tan, Shisan Bao, Kerry-Anne Rye, Philip J Barter and Christina A Bursill
    Citation: Lipids in Health and Disease 2011 10:224
    Content type: Research Published on:

  35. Evidence suggests that physical activity (PA) has a beneficial effect on high-density lipoprotein cholesterol (HDL) and triglycerides. However, observational studies show contrasting results for this associati...

    Authors: Jeroen SL de Munter, Irene G van Valkengoed, Karien Stronks and Charles Agyemang
    Citation: Lipids in Health and Disease 2011 10:223
    Content type: Research Published on:

  36. Synthetic activators of peroxisome proliferator-activated receptors (PPARs) stimulate cholesterol removal from macrophages through PPAR-dependent up-regulation of liver × receptor α (LXRα) and subsequent induc...

    Authors: Ines Kämmerer, Robert Ringseis, Ronald Biemann, Gaiping Wen and Klaus Eder
    Citation: Lipids in Health and Disease 2011 10:222
    Content type: Research Published on:

  37. Bacterial lipases received much attention for their substrate specificity and their ability to function in extreme environments (pH, temperature...). Many staphylococci produced lipases which were released int...

    Authors: Slim Cherif, Sami Mnif, Fatma Hadrich, Slim Abdelkafi and Sami Sayadi
    Citation: Lipids in Health and Disease 2011 10:221
    Content type: Research Published on:

  38. Aging and dyslipidemia are processes which can lead to deleterious consequences to renal function. Therefore, the aim of this study was to determine the effects of both hypercholesterolemia and aging on renal ...

    Authors: Camille M Balarini, Mariana ZT Oliveira, Thiago MC Pereira, Nyam F Silva, Elisardo C Vasquez, Silvana S Meyrelles and Agata L Gava
    Citation: Lipids in Health and Disease 2011 10:220
    Content type: Research Published on:

  39. Among the digestive enzymes, phospholipase A2 (PLA2) hydrolyzes the essential dietary phospholipids in marine fish and shellfish. However, we know little about the organs that produce PLA2, and the ontogeny of th...

    Authors: Zied Zarai, Nicholas Boulais, Pascale Marcorelles, Eric Gobin, Sofiane Bezzine, Hafedh Mejdoub and Youssef Gargouri
    Citation: Lipids in Health and Disease 2011 10:219
    Content type: Research Published on:

  40. Previous studies have demonstrated that long chain fatty acids influence fibroblast function at sub-lethal concentrations. This study is the first to assess the effects of oleic, linoleic or palmitic acids on ...

    Authors: Juliana Magdalon, Elaine Hatanaka, Talita Romanatto, Hosana G Rodrigues, Wilson MT Kuwabara, Caitriona Scaife, Philip Newsholme and Rui Curi
    Citation: Lipids in Health and Disease 2011 10:218
    Content type: Research Published on:

  41. Obese subjects with impaired glucose tolerance (IGT) are more susceptible than healthy individuals to oxidative stress and cardiovascular disease. This randomised controlled investigation was designed to test ...

    Authors: Andrea M McNeilly, Gareth W Davison, Marie H Murphy, Nida Nadeem, Tom Trinick, Ellie Duly, Anna Novials and Jane McEneny
    Citation: Lipids in Health and Disease 2011 10:217
    Content type: Research Published on:

  43. We investigated relationship of low levels of high density lipoprotein cholesterol (HDL-C), high levels of triglycerides, and renal function for the odds, prognosis and survival following acute coronary events...

    Authors: Kuo-Liong Chien, Hung-Ju Lin, Hsiu-Ching Hsu and Ming-Fong Chen
    Citation: Lipids in Health and Disease 2011 10:215
    Content type: Research Published on:

  44. To develop effective strategies in cancer chemoprevention, an increased understanding of endogenous biochemical mediators that block metastatic processes is critically needed. Dietary lipids and non-steroidal ...

    Authors: Paul L Wood, M Amin Khan, Tara Smith and Dayan B Goodenowe
    Citation: Lipids in Health and Disease 2011 10:214
    Content type: Research Published on:

  45. Platelet activating factor (PAF) has been proposed as a key factor and initial trigger in atherosclerosis. Recently, a modulation of PAF metabolism by bioactive food constituents has been suggested. In this st...

    Authors: Constantina Nasopoulou, Alexandros B Tsoupras, Haralabos C Karantonis, Constantinos A Demopoulos and Ioannis Zabetakis
    Citation: Lipids in Health and Disease 2011 10:213
    Content type: Research Published on:

  47. Since the early 1990s, several strains of genetically modified mice have been developed as models for experimental atherosclerosis. Among the available models, the apolipoprotein E-deficient (apoE-/-) mouse is of...

    Authors: Silvana S Meyrelles, Veronica A Peotta, Thiago MC Pereira and Elisardo C Vasquez
    Citation: Lipids in Health and Disease 2011 10:211
    Content type: Review Published on:

  48. Probucol is a unique hypolipidemic agent that decreases high density lipoprotein cholesterol (HDL-C). However, it is not definite that whether probucol hinders the progression of atherosclerosis by improving H...

    Authors: Jian-Kai Zhong, Zhi-Gang Guo, Chen Li, Zhen-Kun Wang, Wen-Yan Lai and Yan Tu
    Citation: Lipids in Health and Disease 2011 10:210
    Content type: Research Published on:

  50. Liver dominates the production and secretion of apolipoprotein B (apoB) and evidence shows that liver malfunction induced by hepatitis B virus (HBV) infection could lead to apolipoprotein metabolism disorders....

    Authors: Fu-Bing Wang, Cheng-liang Zhu, Xinghui Liu and Guo-sheng Gao
    Citation: Lipids in Health and Disease 2011 10:207
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X