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  3. Studies in patients with low HDL have suggested that impaired cellular cholesterol efflux is a heritable phenotype increasing atherosclerosis risk. Less is known about the association of macrophage cholesterol...

    Authors: Patrick Linsel-Nitschke, Henning Jansen, Zouhair Aherrarhou, Stefanie Belz, Björn Mayer, Wolfgang Lieb, Fritz Huber, Werner Kremer, Hans-Robert Kalbitzer, Jeanette Erdmann and Heribert Schunkert
    Citation: Lipids in Health and Disease 2009 8:14
    Content type: Research Published on:

  4. Obesity and its complications lead to vascular injury, atherosclerosis, diabetes and pathological angiogenesis. One of the models to study the obesity and its entanglements is the New Zealand Obese mice model....

    Authors: Adriana Balwierz, Anna Polus, Urszula Razny, Lukasz Wator, Grzegorz Dyduch, Romana Tomaszewska, Stephan Scherneck, Hans Joost and Aldona Dembinska-Kiec
    Citation: Lipids in Health and Disease 2009 8:13
    Content type: Research Published on:

  5. There is a predominance of small and dense LDL cholesterol particles in familial combined hyperlipidemia (FCH). The lipoprotein lipase gene could exert an influence in these circumstances.

    Authors: Antonio López-Ruiz, María M Jarabo, María L Martínez-Triguero, Maria Morales-Suárez-Varela, Eva Solá, Celia Bañuls, Marta Casado and Antonio Hernández-Mijares
    Citation: Lipids in Health and Disease 2009 8:12
    Content type: Short paper Published on:

  6. Dietary fatty acids may modulate inflammation in macrophages of the atherosclerotic plaque, affecting its stability. The n-6 polyunsaturated fatty acid (PUFA) arachidonic acid (AA) generally promotes inflammat...

    Authors: Tiina Solakivi, Tarja Kunnas, Satu Kärkkäinen, Olli Jaakkola and Seppo T Nikkari
    Citation: Lipids in Health and Disease 2009 8:11
    Content type: Short paper Published on:

  7. Hypercholesterolemia is one of the most important factors causing cardiovascular disease (CVD). The aim of the present work was to evaluate the relationships between socio-demographic, clinical, lifestyle and ...

    Authors: Stefanos Tyrovolas, Christos Lionis, Akis Zeimbekis, Vassiliki Bountziouka, Mary Micheli, Alexia Katsarou, Natassa Papairakleous, George Metallinos, Kornilia Makri, Evangelos Polychronopoulos and Demosthenes B Panagiotakos
    Citation: Lipids in Health and Disease 2009 8:10
    Content type: Research Published on:

  8. Omega 3 fatty acids have been found to inhibit proliferation, induce apoptosis, and promote differentiation in various cell types. The processes of cell survival, expansion, and differentiation are of key impo...

    Authors: Melinda E Varney, W Elaine Hardman and Vincent E Sollars
    Citation: Lipids in Health and Disease 2009 8:9
    Content type: Research Published on:

  9. Gamma-linolenic acid is a known inhibitor of tumour cell proliferation and migration in both in vitro and in vivo conditions. The aim of the present study was to determine the mechanisms by which gamma-linolenic ...

    Authors: Juliano Andreoli Miyake, Marcel Benadiba and Alison Colquhoun
    Citation: Lipids in Health and Disease 2009 8:8
    Content type: Research Published on:

  10. A recent in vitro study indicates that IGOB131, a novel seed extract of the traditional West African food plant Irvingia gabonensis, favorably impacts adipogenesis through a variety of critical metabolic pathways...

    Authors: Judith L Ngondi, Blanche C Etoundi, Christine B Nyangono, Carl MF Mbofung and Julius E Oben
    Citation: Lipids in Health and Disease 2009 8:7
    Content type: Research Published on:

  11. The aim of the study is to prepare aqueous dispersions of lipid nanoparticles – flurbiprofen solid lipid nanoparticles (FLUSLN) and flurbiprofen nanostructured lipid carriers (FLUNLC) by hot homogenization fol...

    Authors: Kesavan Bhaskar, Jayaraman Anbu, Velayutham Ravichandiran, Vobalaboina Venkateswarlu and Yamsani Madhusudan Rao
    Citation: Lipids in Health and Disease 2009 8:6
    Content type: Research Published on:

  12. Cognitive deficits are a hallmark feature of both Down Syndrome (DS) and Alzheimer's Disease (AD). Extra copies of the genes on chromosome 21 may also play an important role in the accelerated onset of AD in D...

    Authors: Pamela F Parkinson, Timal S Kannangara, Brennan D Eadie, Braydon L Burgess, Cheryl L Wellington and Brian R Christie
    Citation: Lipids in Health and Disease 2009 8:5
    Content type: Research Published on:

  13. The secreted enzyme autotaxin (ATX) stimulates tumor cell migration, tumorigenesis, angiogenesis, and metastasis. ATX hydrolyzes nucleotides, but its hydrolysis of lysophospholipids to produce lysophosphatidic...

    Authors: Eunjin Koh, Russell W Bandle, David D Roberts, Mary L Stracke and Timothy Clair
    Citation: Lipids in Health and Disease 2009 8:4
    Content type: Research Published on:

  15. Neuropathological, animal, and cell culture studies point to a role for the body's own endogenous cannabinoids (eCBs) system in Alzheimer's disease (AD) pathology and treatment. To date, no published studies h...

    Authors: Jeremy Koppel, Heather Bradshaw, Terry E Goldberg, Houman Khalili, Philippe Marambaud, Michael J Walker, Mauricio Pazos, Marc L Gordon, Erica Christen and Peter Davies
    Citation: Lipids in Health and Disease 2009 8:2
    Content type: Research Published on:

  16. Much attention has been drawn to different alternative strategies for cardiovascular disease prevention. Objective: The aim of the present study was to observe and compare the effects of Enterococcus faecium CRL1...

    Authors: Daniela CU Cavallini, Raquel Bedani, Laura Q Bomdespacho, Regina C Vendramini and Elizeu A Rossi
    Citation: Lipids in Health and Disease 2009 8:1
    Content type: Research Published on:

  17. Available data on the effects of a fermented soy product enriched with Enterococcus faecium and Lactobacillus Jugurti on circulating lipids and adiposity are not completely settled. This study aimed to observe th...

    Authors: Nadia Carla Cheik, Elizeu Antônio Rossi, Ricardo Luís Fernandes Guerra, Neuli Maria Tenório, Cláudia Maria Oller do Nascimento, Fabiana Pavan Viana, Marla Simone Jovenasso Manzoni, Iracilda Zeponni Carlos, Patrícia Leão da Silva, Regina Célia Vendramini and Ana Raimunda Dâmaso
    Citation: Lipids in Health and Disease 2008 7:50
    Content type: Research Published on:

  18. The glyoxylate cycle, which is well characterized in higher plants and some microorganisms but not in vertebrates, is able to bypass the citric acid cycle to achieve fat-to-carbohydrate interconversion. In thi...

    Authors: P Cordero, J Campion, FI Milagro, F Marzo and JA Martinez
    Citation: Lipids in Health and Disease 2008 7:49
    Content type: Short paper Published on:

  19. Deterioration of peroxisomal β-oxidation activity causes an accumulation of very long chain saturated fatty acids (VLCSFA) in various organs. We have recently reported that the levels of VLCSFA in the plasma a...

    Authors: Naotake Yanagisawa, Kazunori Shimada, Tetsuro Miyazaki, Atsumi Kume, Yohei Kitamura, Katsuhiko Sumiyoshi, Takashi Kiyanagi, Takafumi Iesaki, Nao Inoue and Hiroyuki Daida
    Citation: Lipids in Health and Disease 2008 7:48
    Content type: Research Published on:

  20. Small dense LDL is reported to be associated with increased coronary artery disease risk by various epidemiological studies. The gold standard for separation and identification of LDL subtypes in plasma is ult...

    Authors: Yogendra Singh, Ramakrishnan Lakshmy, Ruby Gupta and Vemparala Kranthi
    Citation: Lipids in Health and Disease 2008 7:47
    Content type: Research Published on:

  21. To analyze apolipoprotein gene polymorphisms in the Tunisian population and to check the relation of these polymorphisms and homocysteine, lipid and apolipoprotein levels to the coronary artery disease (CAD).

    Authors: Raoudha Bahri, Esther Esteban, Pedro Moral, Mohsen Hassine, Khaldoun Ben Hamda and Hassen Chaabani
    Citation: Lipids in Health and Disease 2008 7:46
    Content type: Research Published on:

  22. Experimental studies indicate that gamma linolenic acid (GLA) and docosahexaenoic acid (DHA) may inhibit glioma cells growth but effects of oral consumption of these fatty acids on brain tumor fatty acid compo...

    Authors: Javad Nasrollahzadeh, Fereydoun Siassi, Mahmood Doosti, Mohammad Reza Eshraghian, Fazel Shokri, Mohammad Hossein Modarressi, Javad Mohammadi-Asl, Khosro Abdi, Arash Nikmanesh and Seyed Morteza Karimian
    Citation: Lipids in Health and Disease 2008 7:45
    Content type: Research Published on:

  23. Endeavors to manage obesity have been heavily reliant on controlling energy intake and expenditure equilibrium, but have failed to curtail the overweight and obesity epidemic. This dynamic equilibrium is more ...

    Authors: Julius E Oben, Judith L Ngondi and Kenneth Blum
    Citation: Lipids in Health and Disease 2008 7:44
    Content type: Research Published on:

  24. Sleep deprivation in humans has been related to weight gain and consequently, increased risk for insulin resistance. In contrast, there is a significant loss of weight in sleep deprived rats suggesting a state...

    Authors: Ana Barbosa Marcondes de Mattos, Mônica Jordão S Pinto, Cristiane Oliveira, Carolina Biz, Eliane Beraldi Ribeiro, Claudia Maria Oller do Nascimento, Monica Levy Andersen, Sergio Tufik and Lila Missae Oyama
    Citation: Lipids in Health and Disease 2008 7:43
    Content type: Research Published on:

  25. There is a belief among some society that opium has a number of beneficial effects on cardiovascular disease. The aim of the present investigation as a cross-sectional study was to assess this hypothesis. Seve...

    Authors: Sedigheh Asgary, Nizal Sarrafzadegan, Gholam-Ali Naderi and Reza Rozbehani
    Citation: Lipids in Health and Disease 2008 7:42
    Content type: Research Published on:

  26. Phosphatidylethanolamine (PE) is a phospholipid which is biosynthesized into long chain N-acylethanolamines (NAEs) including oleoylethanolamide (OEA), a known inhibitor of food intake. The aim of this study wa...

    Authors: FE Lithander, CM Strik, A-T McGill, AK MacGibbon, BH McArdle and SD Poppitt
    Citation: Lipids in Health and Disease 2008 7:41
    Content type: Research Published on:

  27. Coronary heart disease is increasing in urban Indian subjects and lipid abnormalities are important risk factors. To determine secular trends in prevalence of various lipid abnormalities we performed studies i...

    Authors: Rajeev Gupta, Soneil Guptha, Aachu Agrawal, Vijay Kaul, Kiran Gaur and Vijay P Gupta
    Citation: Lipids in Health and Disease 2008 7:40
    Content type: Research Published on:

  28. We investigated the effects on hemodynamics and gas exchange of a lipid emulsion enriched with omega-3 fatty acids in patients with ARDS.

    Authors: Joan Sabater, Joan Ramon Masclans, Judit Sacanell, Pilar Chacon, Pilar Sabin and Merce Planas
    Citation: Lipids in Health and Disease 2008 7:39
    Content type: Research Published on:

  29. Higher concentrations of serum lipids and apolipoprotein B100 (apoB) are major individual risk factors of atherosclerosis and coronary heart disease. Therefore ameliorative effects of food components against t...

    Authors: Teruyoshi Yanagita, Seo-Young Han, Ying Hu, Koji Nagao, Hideaki Kitajima and Shigeru Murakami
    Citation: Lipids in Health and Disease 2008 7:38
    Content type: Research Published on:

  30. Lowering plasma low density lipoprotein-cholesterol (LDL-C), blood pressure, homocysteine, and preventing platelet aggregation using a combination of a statin, three blood pressure lowering drugs such as a thi...

    Authors: Undurti N Das
    Citation: Lipids in Health and Disease 2008 7:37
    Content type: Hypothesis Published on:

  32. Plant sterols are an established non-pharmacological means to reduce total and LDL blood cholesterol concentrations and are therefore recommended for cholesterol management by worldwide-renown health care inst...

    Authors: Christina Weidner, Michel Krempf, Jean-Marie Bard, Murielle Cazaubiel and Doris Bell
    Citation: Lipids in Health and Disease 2008 7:35
    Content type: Research Published on:

  33. Conjugated linoleic acid (CLA), a naturally occurring anticarcinogen found in dairy products, is an intermediary product of ruminal biohydrogenation of polyunsaturated fatty acids. Few data exist on the CLA co...

    Authors: Spiros N Zlatanos, Kostas Laskaridis and Angelos Sagredos
    Citation: Lipids in Health and Disease 2008 7:34
    Content type: Research Published on:

  34. The APOA1-C3-A5 gene cluster plays an important role in the regulation of lipids. Asian Indians have an increased tendency for abnormal lipid levels and high risk of Coronary Artery Disease (CAD). Therefore, t...

    Authors: Jayashree Shanker, Ganapathy Perumal, Veena S Rao, Natesha B Khadrinarasimhiah, Shibu John, Sridhara Hebbagodi, Manjari Mukherjee and Vijay V Kakkar
    Citation: Lipids in Health and Disease 2008 7:33
    Content type: Research Published on:

  35. The importance of the postprandial state for the early stages of atherogenesis is increasingly acknowledged. We conducted assessment of association between postprandial triglycerides, insulin and glucose after...

    Authors: Diana Rubin, Sandra Claas, Maria Pfeuffer, Michael Nothnagel, Ulrich R Foelsch and Juergen Schrezenmeir
    Citation: Lipids in Health and Disease 2008 7:32
    Content type: Research Published on:

  36. Cow milk is a natural source of the cis 9, trans 11 isomer of conjugated linoleic acid (c9,t11-CLA) and trans vaccenic acid (VA). These fatty acids may be considered as functional foods, and the concentration ...

    Authors: Anna Haug, Per Sjøgren, Nina Hølland, Hanne Müller, Nils P Kjos, Ole Taugbøl, Nina Fjerdingby, Anne S Biong, Eirik Selmer-Olsen and Odd M Harstad
    Citation: Lipids in Health and Disease 2008 7:31
    Content type: Research Published on:

  38. The levels of retinol-binding protein 4 (RBP4) – the carrier protein for Vitamin A in plasma – are tightly regulated under healthy circumstances. The kidney, the main site of RBP4 catabolism, contributes to an...

    Authors: Simone K Frey, Britta Nagl, Andrea Henze, Jens Raila, Beate Schlosser, Thomas Berg, Martin Tepel, Walter Zidek, Martin O Weickert, Andreas FH Pfeiffer and Florian J Schweigert
    Citation: Lipids in Health and Disease 2008 7:29
    Content type: Research Published on:

  40. The impact of L-arginine on atherogenesis and its ability to prevent endothelial dysfunction have been studied extensively during the past years. L-arginine is a substance for nitric oxide synthesis which invo...

    Authors: Mehdi Nematbakhsh, Shaghayegh Haghjooyjavanmard, Farzaneh Mahmoodi and Ali Reza Monajemi
    Citation: Lipids in Health and Disease 2008 7:27
    Content type: Research Published on:

  41. Obesity is related to obstructive sleep apnea-hypopnea syndrome (OSAHS), but its roles in OSAHS as cause or consequence are not fully clarified. Isocapnic intermittent hypoxia (IIH) is a model of OSAHS. We ver...

    Authors: Denis Martinez, Luiz FT Vasconcellos, Patricia G de Oliveira and Signorá P Konrad
    Citation: Lipids in Health and Disease 2008 7:26
    Content type: Research Published on:

  42. To determine plasma apolipoprotein M (apoM) levels and other lipid profiles in hepatocellular carcinoma (HCC) patients compared to other chronic liver diseases and normal subjects.

    Authors: Jingting Jiang, Xiaoying Zhang, Changping Wu, Xihu Qin, Guanghua Luo, Haifeng Deng, Minyang Lu, Bin Xu, Min Li, Mei Ji and Ning Xu
    Citation: Lipids in Health and Disease 2008 7:25
    Content type: Research Published on:

  43. Eicosapentaenoic acid (EPA) is a ώ-3 polyunsaturated fatty acid with anti-inflammatory and anti-cachetic properties that may have potential benefits with regards to skeletal muscle atrophy conditions where inf...

    Authors: Peter Magee, Stephen Pearson and Jeremy Allen
    Citation: Lipids in Health and Disease 2008 7:24
    Content type: Research Published on:

  45. Proprotein convertase subtilisin kexin-like 9 (PCSK9) is a secreted glycoprotein that is transcriptionally regulated by cholesterol status. It modulates levels of circulating low density lipoprotein cholestero...

    Authors: Janice Mayne, Thilina Dewpura, Angela Raymond, Marion Cousins, Anna Chaplin, Karen A Lahey, Stephen A LaHaye, Majambu Mbikay, Teik Chye Ooi and Michel Chrétien
    Citation: Lipids in Health and Disease 2008 7:22
    Content type: Research Published on:

  46. Pgp (P-glycoprotein, MDR1, ABCB1) is an energy-dependent drug efflux pump that is a member of the ATP-binding cassette (ABC) family of proteins. Preliminary studies have reported that nonspecific inhibitors of...

    Authors: Sheila J Thornton, Evelyn Wong, Stephen D Lee and Kishor M Wasan
    Citation: Lipids in Health and Disease 2008 7:21
    Content type: Research Published on:

  49. Increased serum remnant lipoproteins are supposed to predict cardiovascular disease in addition to increased LDL. A new homogenous assay for remnant lipoprotein-cholesterol (RemL-C) has been developed as an al...

    Authors: Hiroshi Yoshida, Hideo Kurosawa, Yuji Hirowatari, Yutaka Ogura, Katsunori Ikewaki, Ikuro Abe, Shinichi Saikawa, Kenichi Domitsu, Kumie Ito, Hidekatsu Yanai and Norio Tada
    Citation: Lipids in Health and Disease 2008 7:18
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X