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  1. Breast cancer is one of the main leading causes of women death. In recent years, attention has been focused on the role of lipoproteins, alterations of cholesterol metabolism and oxidative stress in the molecu...

    Authors: Gabriele Mazzuferi, Tiziana Bacchetti, Md Obaidul Islam and Gianna Ferretti

    Citation: Lipids in Health and Disease 2021 20:143

    Content type: Review

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  2. Effective and applicable predictors of non-alcoholic fatty liver disease (NAFLD) are needed for the non-obese Chinese population. This study was undertaken to investigate: whether serum gamma-glutamyl transfer...

    Authors: Liling Wu, Man Zhang, Haofei Hu and Qijun Wan

    Citation: Lipids in Health and Disease 2021 20:142

    Content type: Research

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  3. The global coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 coronavirus started in March 2020. The conclusions from numerous studies indicate that people with comorbidities, such as arteri...

    Authors: Stanisław Surma, Maciej Banach and Joanna Lewek

    Citation: Lipids in Health and Disease 2021 20:141

    Content type: Review

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  4. Recent studies have substantiated the role of the triglyceride glucose (TyG) index in predicting the prognosis of coronary artery disease (CAD) patients, while no relevant studies have revealed the association...

    Authors: Ang Gao, Jinxing Liu, Chengping Hu, Yan Liu, Yong Zhu, Hongya Han, Yujie Zhou and Yingxin Zhao

    Citation: Lipids in Health and Disease 2021 20:140

    Content type: Research

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  5. Remnant cholesterol (RC) mediates the progression of coronary artery disease, diabetic complications, hypertension, and chronic kidney disease. Limited information is available on the association of RC with no...

    Authors: Yang Zou, Jianyun Lan, Yanjia Zhong, Shuo Yang, Huimin Zhang and Guobo Xie

    Citation: Lipids in Health and Disease 2021 20:139

    Content type: Research

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  6. Lipid management is the first line of treatment for decreasing the incidence of cardiovascular events in patients with coronary heart disease (CHD), and a variety of indicators are used to evaluate lipid manag...

    Authors: Jiacheng Lai, Yongsheng Han, Chongjian Huang, Bin Li, Jingshu Ni, Meili Dong, Yikun Wang and Qingtong Wang

    Citation: Lipids in Health and Disease 2021 20:137

    Content type: Research

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  7. Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease and cirrhosis. NAFLD is mediated by changes in lipid metabolism and known risk factors include obesity, metabolic syndrome, ...

    Authors: Yvonne N. Flores, Aryana T. Amoon, Baolong Su, Rafael Velazquez-Cruz, Paula Ramírez-Palacios, Jorge Salmerón, Berenice Rivera-Paredez, Janet S. Sinsheimer, Aldons J. Lusis, Adriana Huertas-Vazquez, Sammy Saab, Beth A. Glenn, Folasade P. May, Kevin J. Williams, Roshan Bastani and Steven J. Bensinger

    Citation: Lipids in Health and Disease 2021 20:136

    Content type: Research

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  8. Dysregulated lipid metabolism is critically involved in the development of hepatocellular carcinoma (HCC). The respective metabolic pathways affected in HCC can be identified using suitable experimental models...

    Authors: Elisabeth M. Haberl, Rebekka Pohl, Lisa Rein-Fischboeck, Marcus Höring, Sabrina Krautbauer, Gerhard Liebisch and Christa Buechler

    Citation: Lipids in Health and Disease 2021 20:135

    Content type: Research

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  9. Conicity index, body-shape index, lipid accumulation product (LAP), waist circumference (WC), triglyceride, triglyceride-glucose (TyG) index, hepatic steatosis index (HSI), waist-to-height ratio (WHtR), TyG in...

    Authors: Guotai Sheng, Song Lu, Qiyang Xie, Nan Peng, Maobin Kuang and Yang Zou

    Citation: Lipids in Health and Disease 2021 20:134

    Content type: Research

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  10. Blood lipids are essential components for cellular growth. An inverse association between serum lipid levels and risk of cancer has led to a controversy among previous studies. The aim of this prospective coho...

    Authors: Yu-Chen Chang, Chien-Ju Lin, Tzu-Lin Yeh, Ming-Chieh Tsai, Le-Yin Hsu, Kuo-Liong Chien and Hsin-Yin Hsu

    Citation: Lipids in Health and Disease 2021 20:133

    Content type: Research

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  11. The relationship between nonalcoholic fatty liver disease (NAFLD) and obesity-related indices has been analyzed separately thus far, and evidence comparing these indices together is still lacking, especially i...

    Authors: Fangfei Xie, Yuyu Pei, Quan Zhou, Deli Cao and Yun Wang

    Citation: Lipids in Health and Disease 2021 20:132

    Content type: Research

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  12. Limited studies regarding the correlation of lipid accumulation product (LAP) with a decreased estimated glomerular filtration rate (eGFR) have yielded conflicting findings, and no report has demonstrated the ...

    Authors: Pijun Yan, Yong Xu, Ying Miao, Qian Tang, Yuru Wu, Xue Bai, Zhihong Zhang, Qian Li and Qin Wan

    Citation: Lipids in Health and Disease 2021 20:131

    Content type: Research

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  13. High serum Lipoprotein(a) (Lp(a)) level and Apolipoprotein B/Apolipoprotein AΙ (ApoB/ApoA-Ι) ratio are risk factors for cardiovascular disease and kidney disease and have been found to be correlated with the p...

    Authors: Jun Tao, Wen Dai, Chenglin Ye, Qian Yao, Man Zhou and Yan Li

    Citation: Lipids in Health and Disease 2021 20:130

    Content type: Research

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  14. Mycobacterium tuberculosis (Mtb), the main etiology of tuberculosis (TB), is predominantly an intracellular pathogen that has caused infection, disease and death in humans for centuries. Lipid droplets (LDs) are ...

    Authors: Daniel Mekonnen, Awoke Derbie, Adane Mihret, Solomon Abebe Yimer, Tone Tønjum, Baye Gelaw, Endalkachew Nibret, Abaineh Munshae, Simon J. Waddell and Abraham Aseffa

    Citation: Lipids in Health and Disease 2021 20:129

    Content type: Review

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  15. Evidence suggests that proteins related to lipid metabolism, such as apolipoproteins, play an important role in the maintenance of normal vision. While several members of the apolipoprotein family are abundant...

    Authors: Parth A. Patel, Tae Jin Lee, Sai Karthik Kodeboyina, Garrett Jones, Kathryn Bollinger, Lane Ulrich, David Bogorad, Amy Estes, Wenbo Zhi, Shruti Sharma and Ashok Sharma

    Citation: Lipids in Health and Disease 2021 20:128

    Content type: Research

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  16. Coronary artery disease (CAD) is a common cardiovascular disease, and abnormal blood lipid metabolism is an important risk factor. Transforming growth factor-ß (TGF-ß) and its receptor (TGF-ßR) can inhibit the...

    Authors: Haibin Chen, Yiping Wang, Bing Sun, Xunxia Bao, Yu Tang, Feifei Huang, Sibo Zhu and Jiahong Xu

    Citation: Lipids in Health and Disease 2021 20:127

    Content type: Research

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  17. The coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2). At present, the COVID-19 has been prevalent worldwide for more than a year and caused...

    Authors: Yanlan Xu, Xinyu Yang, Hua Bian and Mingfeng Xia

    Citation: Lipids in Health and Disease 2021 20:126

    Content type: Review

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  18. Abnormalities in serum lipids and lipoproteins have been documented to link to the risk of cancers in recent years, but its prognostic value for cancer is not known. This study retrospectively evaluated the si...

    Authors: Cong Ma, Xiaoyan Wang, Jingjing Guo and Ping Liu

    Citation: Lipids in Health and Disease 2021 20:69

    Content type: Research

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  19. Research on dyslipidemia during pregnancy in women with gestational diabetes mellitus (GDM) has rarely been conducted in Asia. The present study aimed to evaluate maternal mid-trimester lipid profile in relati...

    Authors: Yuan Li, Xiaoqian Wang, Fengjuan Jiang, Wenqing Chen, Jie Li and Xiaotian Chen

    Citation: Lipids in Health and Disease 2021 20:125

    Content type: Research

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  20. Large observational studies have shown that small, dense LDL subfractions are related to atherosclerotic cardiovascular disease. This study assessed the effects of two highly effective lipid-lowering therapies...

    Authors: Leticia C. S. Pinto, Ana P. Q. Mello, Maria C. O. Izar, Nagila R. T. Damasceno, Antonio M. F. Neto, Carolina N. França, Adriano Caixeta, Henrique T. Bianco, Rui M. S. Póvoa, Flavio T. Moreira, Amanda S. F. Bacchin and Francisco A. Fonseca

    Citation: Lipids in Health and Disease 2021 20:124

    Content type: Research

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  21. The relationship between the APOE gene polymorphism and lipid profiles and atrial fibrillation (AF) remains controversial. The current study purposed to investigate how the APOE gene SNPs (rs429358 and rs7412) an...

    Authors: Xunwei Deng, Jingyuan Hou, Qiaoting Deng and Zhixiong Zhong

    Citation: Lipids in Health and Disease 2021 20:123

    Content type: Research

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  22. Idiopathic membranous nephropathy (IMN) may have various clinical outcomes. Hyperlipidemia is quite common in IMN. However, the utility of the lipid profile in predicting outcomes remains unknown. This study a...

    Authors: Lei Dong, Wang Wei, Min Han and Gang Xu

    Citation: Lipids in Health and Disease 2021 20:122

    Content type: Research

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  23. Current studies support lipid ratios [the total cholesterol (TC)/high-density lipoprotein cholesterol (HDL-C) ratio; the triglyceride (TG)/HDL-C ratio; the low-density lipoprotein cholesterol (LDL -C)/HDL-C ra...

    Authors: Yu Yu, Tian Lan, Dandan Wang, Wangsheng Fang, Yu Tao, Minghui Li, Xiao Huang, Wei Zhou, Tao Wang, Lingjuan Zhu, Huihui Bao and Xiaoshu Cheng

    Citation: Lipids in Health and Disease 2021 20:121

    Content type: Research

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  24. Life expectancy has greatly increased, generating an improvement in screening programs for disease prevention, lifesaving drugs and medical devices. The impact of lowering low-density lipoprotein cholesterol (...

    Authors: Yehudit Eden Friedman, David M. Steinberg, Michal Canetti, Ido Cohen, Shlomo Segev and Ophira Salomon

    Citation: Lipids in Health and Disease 2021 20:120

    Content type: Research

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  25. Blood lipid increases during gestation are considered a physiological adaption, and decrease after delivery. However, some adverse pregnancy outcomes are thought to be related to gestational lipid levels. Ther...

    Authors: Yandi Zhu, Haiyan Zhu, Qinyu Dang, Qian Yang, Dongxu Huang, Yadi Zhang, Xiaxia Cai and Huanling Yu

    Citation: Lipids in Health and Disease 2021 20:119

    Content type: Research

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  26. The present study was aimed to establish a prediction model for in-stent restenosis (ISR) in subjects who had undergone percutaneous coronary intervention (PCI) with drug-eluting stents (DESs).

    Authors: Min-Tao Gai, Bing Zhu, Xiao-Cui Chen, Fen Liu, Xiang Xie, Xiao-Ming Gao, Xiang Ma, Zhen-Yan Fu, Yi-Tong Ma and Bang-dang Chen

    Citation: Lipids in Health and Disease 2021 20:118

    Content type: Research

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  27. Angiopoietin-like proteins (ANGPTL), primarily 3, 4, and 8, play a major role in maintaining energy homeostasis by regulating triglyceride metabolism. This study evaluated the level of ANGPTL3, 4, and 8 in the...

    Authors: Hossein Arefanian, Irina Al-Khairi, Nermeen Abu Khalaf, Preethi Cherian, Sina Kavalakatt, Dhanya Madhu, Aditi Mathur, Mohamed G. Qaddoumi, Fahd Al-Mulla, Jehad Abubaker and Mohamed Abu-Farha

    Citation: Lipids in Health and Disease 2021 20:117

    Content type: Research

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  28. Dyslipidemia is a predisposing factor for coronary heart disease (CHD). High-intensity statin therapy is recommended as secondary prevention. ABCB1 and SLCO1B1 genes influence the efficacy and safety of statin...

    Authors: Tingting Wang, Li Sun, Li Xu, Ting Zhao, Jie Feng, Luhai Yu, Jianhua Wu and Hongjian Li

    Citation: Lipids in Health and Disease 2021 20:116

    Content type: Research

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  29. Cancer-associated cachexia (CAC) is a metabolic syndrome characterized by progressive depletion of adipose and muscle tissue that cannot be corrected by conventional nutritional therapy. Adipose tissue, an imp...

    Authors: Diya Sun, Zuoyou Ding, Lei Shen, Fan Yang, Jun Han and Guohao Wu

    Citation: Lipids in Health and Disease 2021 20:115

    Content type: Research

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  30. Previous epidemiological studies have indicated the seasonal variability of serum lipid levels. However, little research has explicitly examined the separate secular and seasonal trends of dyslipidemia. The pr...

    Authors: Jiahui Lao, Yafei Liu, Yang Yang, Peng Peng, Feifei Ma, Shuang Ji, Yujiao Chen and Fang Tang

    Citation: Lipids in Health and Disease 2021 20:114

    Content type: Research

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  31. Hypertriglyceridemia has emerged as a critical coronary artery disease (CAD) risk factor. Rare loss-of-function (LoF) variants in apolipoprotein C-III have been reported to reduce triglycerides (TG) and are ca...

    Authors: Shiwali Goyal, Yosuke Tanigawa, Weihua Zhang, Jin-Fang Chai, Marcio Almeida, Xueling Sim, Megan Lerner, Juliane Chainakul, Jonathan Garcia Ramiu, Chanel Seraphin, Blair Apple, April Vaughan, James Muniu, Juan Peralta, Donna M. Lehman, Sarju Ralhan…

    Citation: Lipids in Health and Disease 2021 20:113

    Content type: Research

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  32. Increased physical activity is inversely related to the risk to develop cardiovascular disease (CVD). In a recent systematic review, it was reported that CVD patients had an increased cholesterol absorption an...

    Authors: S. Mashnafi, J. Plat, R. P. Mensink, P. J. Joris, J. P. D. Kleinloog and S. Baumgartner

    Citation: Lipids in Health and Disease 2021 20:112

    Content type: Research

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  33. Limited data are available for validation of low-density lipoprotein cholesterol (LDL) calculation (LDLcal) in the adult Korean population. The aim of this study was to develop and validate a new equation for LDL

    Authors: Rihwa Choi, Mi-Jung Park, Youngju Oh, Sung Ho Kim, Sang Gon Lee and Eun Hee Lee

    Citation: Lipids in Health and Disease 2021 20:111

    Content type: Research

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  34. Previous studies show that abnormal lipoprotein metabolism can increase the prevalence of chronic kidney disease (CKD). This study prospectively investigated the association of triglycerides to high-density li...

    Authors: Shiqi Lv, Han Zhang, Jing Chen, Ziyan Shen, Cheng Zhu, Yulu Gu, Xixi Yu, Di Zhang, Yulin Wang, Xiaoqiang Ding and Xiaoyan Zhang

    Citation: Lipids in Health and Disease 2021 20:110

    Content type: Research

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  35. Cancer patients often exhibit chemotherapy-associated changes in serum lipid profiles, however, their prognostic value before and after adjuvant chemotherapy on survival among non-small-cell lung cancer (NSCLC...

    Authors: Fan Luo, Kang-mei Zeng, Jia-xin Cao, Ting Zhou, Su-xia Lin, Wen-juan Ma, Yun-peng Yang, Zhong-han Zhang, Fei-teng Lu, Yan Huang, Hong-yun Zhao and Li Zhang

    Citation: Lipids in Health and Disease 2021 20:109

    Content type: Research

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  36. The current study was conducted to explore the effects of chemerin and homocysteine (Hcy) levels and their associations with the occurrence and development of ischemic cerebrovascular disease (ICVD).

    Authors: Lixuan Wang, Jianpu Jia, Zhen Hong, Leguo Zhang and Junling Zhang

    Citation: Lipids in Health and Disease 2021 20:108

    Content type: Research

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  37. Dyslipidemia is a feature of impaired metabolic health in conjunction with impaired glucose metabolism and central obesity. However, the contribution of factors to postprandial lipemia in healthy but metabolic...

    Authors: Stephanie M. Wilson, Adam P. Maes, Carl J. Yeoman, Seth T. Walk and Mary P. Miles

    Citation: Lipids in Health and Disease 2021 20:107

    Content type: Research

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  38. Proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitors have been demonstrated to produce significantly greater reduction in LDL cholesterol levels and cardiovascular events than standard statin thera...

    Authors: Fei Gao, Zhi Jian Wang, Xiao Teng Ma, Hua Shen, Li Xia Yang and Yu Jie Zhou

    Citation: Lipids in Health and Disease 2021 20:106

    Content type: Research

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  39. Low-density lipoprotein cholesterol (LDL-C) independently impacts aging-related health outcomes and plays a critical role in cardiovascular diseases (CVDs). However, there are limited predictive data on all-ca...

    Authors: Ryuichi Kawamoto, Asuka Kikuchi, Taichi Akase, Daisuke Ninomiya and Teru Kumagi

    Citation: Lipids in Health and Disease 2021 20:105

    Content type: Research

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  40. Colorectal cancer (CRC) is a malignancy of the large intestine, whose development and prognosis have been demonstrated to be associated with altered lipid metabolism. High cholesterol intake is associated with...

    Authors: Ryuk Jun Kwon, Eun-Ju Park, Sang Yeoup Lee, Youngin Lee, Chungsu Hwang, Choongrak Kim and Young Hye Cho

    Citation: Lipids in Health and Disease 2021 20:104

    Content type: Research

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  41. Low-density lipoprotein cholesterol (LDL-C) metabolic disorder is common in individuals with diabetes. The role of LDL-C in mild cognitive impairment (MCI) remains to be explored. We aim to investigate the ass...

    Authors: Haoqiang Zhang, Wenwen Zhu, Tong Niu, Zheng Wang, Ke An, Wuyou Cao, Jijing Shi and Shaohua Wang

    Citation: Lipids in Health and Disease 2021 20:103

    Content type: Research

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  42. Canola oil (Can) and several vegetable oils shorten the lifespan of stroke-prone spontaneously hypertensive rats (SHRSP). Although similar lifespan shortening has been reported for partially hydrogenated Can, ...

    Authors: Kenjiro Tatematsu, Daisuke Miyazawa, Yoshiaki Saito, Harumi Okuyama and Naoki Ohara

    Citation: Lipids in Health and Disease 2021 20:102

    Content type: Research

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  43. As an autosomal dominant disorder, familial hypercholesterolemia (FH) is mainly attributed to disease-causing variants in the low-density lipoprotein receptor (LDLR) gene. The aim of this study was to explore the...

    Authors: Haochang Hu, Ruoyu Chen, Yingchu Hu, Jian Wang, Shaoyi Lin and Xiaomin Chen

    Citation: Lipids in Health and Disease 2021 20:101

    Content type: Research

    Published on:

  44. The deleterious effect of maternal high-fat diet (HFD) on the fetal rat liver may cause later development of non-alcoholic fatty liver disease (NAFLD). The aim of this study was to evaluate the effect of mater...

    Authors: Szu-Wei Huang, Yu-Che Ou, Kuo-Shu Tang, Hong-Ren Yu, Li-Tung Huang, You-Lin Tain, I-Chun Lin, Jiunn-Ming Sheen, Chih-Yao Hou, Ching-Chou Tsai and Mao-Meng Tiao

    Citation: Lipids in Health and Disease 2021 20:100

    Content type: Research

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  45. Triglyceride glucose-body mass index (TyG-BMI) has been proven to be a reliable substitute for insulin resistance. However, whether a causal association exists between TyG-BMI and new-onset diabetes remains un...

    Authors: Xiaoyu Wang, Jingdong Liu, Zongyou Cheng, Yanjia Zhong, Xiaohua Chen and Wei Song

    Citation: Lipids in Health and Disease 2021 20:99

    Content type: Research

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  46. The incidence of severe (S-HTG) and very severe hypertriglyceridemia (VS-HTG) among Canadians is unknown. This study aimed to determine the incidence, characteristics, predictors and care patterns for individu...

    Authors: Amanda J. Berberich, Alexandra M. Ouédraogo, Salimah Z. Shariff, Robert A. Hegele and Kristin K. Clemens

    Citation: Lipids in Health and Disease 2021 20:98

    Content type: Research

    Published on:

  47. Pancreaticobiliary reflux (PBR) causes chronic inflammation of the gallbladder mucosa and changes in the bile components, which are known to promote gallstone formation. This study aimed to investigate the bil...

    Authors: Yukai Xiang, Xiangyu Kong, Cheng Zhang, Chuanqi He, Jingli Cai, Ruiqi Lu, Bosen Zhang, Liu Lu and Yulong Yang

    Citation: Lipids in Health and Disease 2021 20:97

    Content type: Research

    Published on:

  48. Maresin-1 (MaR1) is an anti-inflammatory pro-resolving mediator and is considered a potential regulator of metabolic diseases. Non-alcoholic fatty liver disease (NAFLD) is a very common metabolic liver disease...

    Authors: Xia Fang, Hongya Wang, Ting Ye, Xiaolan Fu, Xiaozhen Tan, Yan Zeng, Jiahao Fan and Yong Xu

    Citation: Lipids in Health and Disease 2021 20:96

    Content type: Research

    Published on:

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