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  1. As the second cause of cancer death in women, breast cancer has become a worldwide priority. Previous studies based on tumour cell lines demonstrated that arachidonic acid (AA) and its metabolites promote canc...

    Authors: Wenge Li, Xiaoyu Guo, Changzheng Chen and Juanjuan Li
    Citation: Lipids in Health and Disease 2022 21:103
    Content type: Research Published on:

  2. Visceral obesity is associated with cancer incidence and prognosis. Altered lipid profiles are frequently seen in visceral obese patients. The blood test of lipid profiles is more convenient and has no radical...

    Authors: Bo Gao, Xiangrui Li, Wenqing Chen, Shu’an Wang, Jian He, Yu Liu, Chao Ding and Xiaotian Chen
    Citation: Lipids in Health and Disease 2022 21:102
    Content type: Research Published on:

  3. Many cardiovascular disorders, including atherosclerosis, hypertension, coronary heart disease, diabetes, etc., are characterized by endothelial cell dysfunction. Endothelial cell function is closely related t...

    Authors: Yali Lai, Yue Tian, Xintong You, Jiangnan Du and Jianmei Huang
    Citation: Lipids in Health and Disease 2022 21:101
    Content type: Review Published on:

  4. Sitosterolemia (STSL) is an extremely rare genetic disease. Xanthomas as the first symptom are frequently misinterpreted as familial hypercholesterolemia (FH) in children. Inappropriate treatment may deteriora...

    Authors: Jun Zhang, Qiu-li Chen, Song Guo, Yan-hong Li, Chuan Li, Ru-jiang Zheng, Xue-qun Luo and Hua-mei Ma
    Citation: Lipids in Health and Disease 2022 21:100
    Content type: Research Published on:

  5. The prevalence of gestational diabetes mellitus (GDM) is increasing worldwide. There is increasing evidence that GDM is a heterogeneous disease with different subtypes. An important question in this context is...

    Authors: Moritz Liebmann, Katharina Grupe, Melissa Asuaje Pfeifer, Ingo Rustenbeck and Stephan Scherneck
    Citation: Lipids in Health and Disease 2022 21:99
    Content type: Research Published on:

  6. Although obesity is caused by different factors, individual susceptibility to obesity differs among people under the same circumstances. The microbiota in the caecum or fresh faeces and metabolites in blood or...

    Authors: Yueshan Pang, Yali Zheng, Ni Yang, Meng Zan, Lu Zhang and WeiJun Ding
    Citation: Lipids in Health and Disease 2022 21:98
    Content type: Research Published on:

  7. Cholesterol gallstone disease (CGD) is accompanied by biliary cholesterol supersaturation. Hepatic Niemann-Pick C1-like 1 (NPC1L1), which is present in humans but not in wild-type (WT) mice, promotes hepatocyt...

    Authors: Pingfan Mo, Hongtan Chen, Xin Jiang, Fengling Hu, Fenming Zhang, Guodong Shan, Wenguo Chen, Sha Li, Yiqiao Li and Guoqiang Xu
    Citation: Lipids in Health and Disease 2022 21:97
    Content type: Research Published on:

  8. To explore the relationship between the fatty acid lipophilic index (LI) of the erythrocyte membrane and oral cancer risk, as well as to evaluate the possibility of LI acting as a mediator of the association b...

    Authors: Yi Fan, Qing Chen, Yaping Wang, Jing Wang, Yanni Li, Sijie Wang, Yanfeng Weng, Qiujiao Yang, Chen Chen, Lisong Lin, Yu Qiu, Fa Chen, Jing Wang, Baochang He and Fengqiong Liu
    Citation: Lipids in Health and Disease 2022 21:96
    Content type: Research Published on:

  9. Traditional and non-traditional (TNNT) lipid indicators are known to be closely related to nonalcoholic fatty liver disease (NAFLD). This study’s objective was to compare the degree of associations and diagnos...

    Authors: Song Lu, Maobin Kuang, Jinjing Yue, Chong Hu, Guotai Sheng and Yang Zou
    Citation: Lipids in Health and Disease 2022 21:95
    Content type: Research Published on:

  10. The tumor microenvironment (TME) is characterized by discrete changes in metabolic features of cancer and immune cells, with various implications. Cancer cells take up most of the available glucose to support ...

    Authors: Wanshuang Lou, Chaoju Gong, Zhuoni Ye, Ynayan Hu, Minjing Zhu, Zejun Fang and Huihui Xu
    Citation: Lipids in Health and Disease 2022 21:94
    Content type: Review Published on:

  11. Anti-thymoglobulin (ATG)-based immunosuppressive treatment (IST) is the standard first-line management for patients with severe AA/very severe AA (SAA/VSAA) and is not suitable for allogeneic stem cell transpl...

    Authors: Qi Liu, Huijie Dong, Yuzhu Li, Yingying Shen, Yilei Hong, Ying Chen, Shan Liu, Xiaolian Wu, Wenbin Liu, Huijin Hu, Yuechao Zhao, Shenyun Lin, Yiping Shen, Yuhong Zhou, Baodong Ye and Dijiong Wu
    Citation: Lipids in Health and Disease 2022 21:93
    Content type: Research Published on:

  12. Improving dietary fat quality strongly affects serum cholesterol levels and hence the risk of cardiovascular diseases (CVDs). Recent studies have identified dietary fat as a potential modulator of the gut micr...

    Authors: Vibeke H. Telle-Hansen, Line Gaundal, Nasser Bastani, Ida Rud, Marte G. Byfuglien, Terje Gjøvaag, Kjetil Retterstøl, Kirsten B. Holven, Stine M. Ulven and Mari C. W. Myhrstad
    Citation: Lipids in Health and Disease 2022 21:92
    Content type: Research Published on:

  13. Essential phospholipids (EPL) have hepatoprotective effects across many liver diseases/conditions. The impact of EPL on hepatocyte function in vitro was investigated.

    Authors: Dominik Wupperfeld, Gert Fricker, Béatrice Bois De Fer, Larissa Frank, Annika Wehrle and Branko Popovic
    Citation: Lipids in Health and Disease 2022 21:91
    Content type: Research Published on:

  15. Alcohol-related liver disease (ALD) is a major chronic liver ailment caused by alcohol overconsumption and abuse. Apolipoprotein H (APOH) participates in lipid metabolism and might have a potential regulatory ...

    Authors: Yaming Liu, Zhe Wu, Yong Zhang, Binbin Chen, Shuqi Yu, Wanyun Li and Jianlin Ren
    Citation: Lipids in Health and Disease 2022 21:89
    Content type: Research Published on:

  16. Although dyslipidaemia may have a crucial impact on cardiovascular health in adults, there is a lack of specific data in transitional-age youth. Therefore, this study attempted to evaluate the association of d...

    Authors: Jia-Xing Zhang, Wen Li, Xiu-Juan Tao, Chen Chen, Qing-An Wang, Wan-Lu Liu, Chan Yang, Kai-Rong Wang, Jiang-Wei Qiu, Yi Zhao and Yu-Hong Zhang
    Citation: Lipids in Health and Disease 2022 21:88
    Content type: Research Published on:

  17. Hyperlipidaemia is an important factor that induces coronary artery disease (CAD). This study aimed to explore the lipid metabolism patterns and relevant clinical and molecular features of coronary artery dise...

    Authors: Yanhui Liao, Zhenzhen Dong, Hanhui Liao, Yang Chen, Longlong Hu, Zuozhong Yu, Yi Xia, Yuanbin Zhao, Kunpeng Fan, Jingwen Ding, Xiongda Yao, Tianhua Deng and Renqiang Yang
    Citation: Lipids in Health and Disease 2022 21:87
    Content type: Research Published on:

  18. This study aimed to examine whether the neutrophil to high-density lipoprotein cholesterol ratio (NHR) can predict cardiovascular outcomes in normoglycemic individuals with elevated fasting glucose levels.

    Authors: Shuo-Lin Liu, Bao-Yu Feng, Qi-Rui Song, Ying-Mei Zhang, Shuo-Ling Wu and Jun Cai
    Citation: Lipids in Health and Disease 2022 21:86
    Content type: Research Published on:

  19. Doxorubicin (DOX) is an anthracycline antibiotic frequently used against a wide range of cancers, including breast cancer. Although the drug is effective as a treatment against cancer, many patients develop he...

    Authors: Carmelita Abrahams, Nicholas J. Woudberg and Sandrine Lecour
    Citation: Lipids in Health and Disease 2022 21:85
    Content type: Review Published on:

  20. Epidemiological and clinical evidence suggests that high-dose intake of omega 3 fatty acids (n-3 FA) have a favorable role in altering serum triglycerides (TG) and non-high density lipoprotein cholesterol (non...

    Authors: Gediz Dogay Us and Sohail Mushtaq
    Citation: Lipids in Health and Disease 2022 21:84
    Content type: Research Published on:

  21. Despite having a 92% concentration of saturated fatty acid composition, leading to an apparently unfavorable lipid profile, body weight and glycemic effect, coconut oil is consumed worldwide. Thus, we conducte...

    Authors: Ana Cláudia Duarte, Bernardo Frison Spiazzi, Carolina Pires Zingano, Eduarda Nunes Merello, Laura Fink Wayerbacher, Paula Portal Teixeira, Laura Penso Farenzena, Carina de Araujo, Carmen Raya Amazarray, Verônica Colpani and Fernando Gerchman
    Citation: Lipids in Health and Disease 2022 21:83
    Content type: Research Published on:

  22. Hypoxia is a common feature of laryngocarcinoma. Alterations in lipid metabolism are an important metabolic rewiring phenomenon for malignant cells to maintain their rapid proliferation in the hypoxic microenv...

    Authors: Minlan Yang, Sa Wu, Weisong Cai, Xiaoping Ming, Yuhao Zhou and Xiong Chen
    Citation: Lipids in Health and Disease 2022 21:82
    Content type: Research Published on:

  23. The present article aims to discuss the hypothesis that skeletal muscle per se but mostly its muscle fiber composition could be significant determinants of lipid metabolism and that certain exercise modalities...

    Authors: Tzortzis Nomikos, Spyridon Methenitis and Demosthenes B Panagiotakos
    Citation: Lipids in Health and Disease 2022 21:81
    Content type: Hypothesis Published on:

  24. Chronic pain in adolescence is associated with diminished outcomes, lower socioeconomic status in later life, and decreased family well-being. Approximately one third of adolescents with chronic pain have obes...

    Authors: Paula A. Gonzalez, Judith Simcox, Hershel Raff, Gina Wade, Helaina Von Bank, Steven Weisman and Keri Hainsworth
    Citation: Lipids in Health and Disease 2022 21:80
    Content type: Research Published on:

  25. Acute myeloid leukemia (AML) is the most common malignancy of the hematological system, and there are currently a number of studies regarding abnormal alterations in energy metabolism, but fewer reports relate...

    Authors: Hai-Bin Zhang, Zhuo-Kai Sun, Fang-Min Zhong, Fang-Yi Yao, Jing Liu, Jing Zhang, Nan Zhang, Jin Lin, Shu-Qi Li, Mei-Yong Li, Jun-Yao Jiang, Ying Cheng, Shuai Xu, Xue-Xin Cheng, Bo Huang and Xiao-Zhong Wang
    Citation: Lipids in Health and Disease 2022 21:79
    Content type: Research Published on:

  26. Lipoprotein(a) [Lp(a)] is a recognized risk factor for ischemic stroke (IS); however, its role in thromboembolism in patients with non-valvular atrial fibrillation (NVAF) remains controversial. We aimed to ass...

    Authors: Jie Song, Xiaoxue Zhang, Meng Wei, Yakun Bo, Xianhui Zhou and Baopeng Tang
    Citation: Lipids in Health and Disease 2022 21:78
    Content type: Research Published on:

  27. The prevalence of cardiovascular disease (CVD) is high in China, especially in Northwest China, and dyslipidemia in diabetes is a major factor at risk for CVD. The dyslipidemia prevalence, treatment and contro...

    Authors: Jiahang Li, Zhenxing Nie, Zhongli Ge, Lei Shi, Bin Gao and Yan Yang
    Citation: Lipids in Health and Disease 2022 21:77
    Content type: Research Published on:

  29. Psoriasis is a chronic inflammatory skin disorder related to dyslipidemia, with decreased high-density lipoprotein (HDL). Various cell types express phospholipid transfer protein (PLTP) as well as cholesteryl ...

    Authors: Jun Chen, Haihua Qi, Lijun Liu, Yandong Niu, Shuping Yu, Shucun Qin and Lei He
    Citation: Lipids in Health and Disease 2022 21:75
    Content type: Research Published on:

  30. Whereas the dietary intake of industrial trans fatty acids (iTFA) has been specifically associated with inflammation, cardiovascular disease, and type 2 diabetes, understanding the impact of dietary fats on human...

    Authors: Dominik Guggisberg, Kathryn J. Burton-Pimentel, Barbara Walther, René Badertscher, Carola Blaser, Reto Portmann, Alexandra Schmid, Thomas Radtke, Hugo Saner, Nadine Fournier, Ueli Bütikofer and Guy Vergères
    Citation: Lipids in Health and Disease 2022 21:74
    Content type: Research Published on:

  32. The correlation between nontraditional lipids and ischemic stroke (IS) is inconsistent and controversial. This study aimed to examine the association of four nontraditional lipids with IS risk in Chinese adults.

    Authors: Minhua Tang, Qi Zhao, Kangqi Yi, Yiling Wu, Yu Xiang, Shuheng Cui, Xuyan Su, Yuting Yu, Genming Zhao and Yonggen Jiang
    Citation: Lipids in Health and Disease 2022 21:72
    Content type: Research Published on:

  33. Maternal lipid levels during pregnancy are critical for fetal development. Recent studies revealed that high-density lipoprotein cholesterol (HDL-c) levels during pregnancy were negatively correlated with birt...

    Authors: Dongxu Huang, Haiyan Zhu, Yandi Zhu, Qinyu Dang, Qian Yang, Yadi Zhang, Xiaxia Cai, Xiaoyan Zhao, Ning Liang, Hongliang Wang and Huanling Yu
    Citation: Lipids in Health and Disease 2022 21:71
    Content type: Research Published on:

  34. Insulin resistance, liver injury and dyslipidemia are reported in non-alcoholic fat liver disease (NAFLD) patients. Interleukin (IL)-38 may take part in the pathophysiology of insulin resistance. Nevertheless,...

    Authors: Jun Cao, Lin Hua, Shipei Zhang, Jinping Tang, Fan Ke, Zhouhuan Wu and Guohui Xue
    Citation: Lipids in Health and Disease 2022 21:70
    Content type: Research Published on:

  35. Pulmonary arterial hypertension (PAH) is a chronic, progressive lung vascular disease accompanied by elevated pulmonary vascular pressure and resistance, and it is characterized by increased pulmonary artery s...

    Authors: Jingyuan Chen, Jun Luo, Haihua Qiu, Yi Tang, Xiaojie Yang, Yusi Chen, Zilu Li and Jiang Li
    Citation: Lipids in Health and Disease 2022 21:69
    Content type: Research Published on:

  36. Previous studies have shown that at a similar body mass index, Middle Eastern immigrants are more insulin resistant and at higher risk for type 2 diabetes (T2D) than native Europeans. Insulin resistance is str...

    Authors: Karin G. Stenkula, Lisa Esbjörnsson Klemendz, Claes Fryklund, Nils Wierup, Wathik Alsalim, Mona Landin-Olsson, Lena Trinh, Sven Månsson and Louise Bennet
    Citation: Lipids in Health and Disease 2022 21:68
    Content type: Research Published on:

  37. Inflammatory breast cancer (IBC) represents a deadly aggressive phenotype of breast cancer (BC) with a unique clinicopathological presentation and low survival rate. In fact, obesity represents an important ri...

    Authors: Aya Saber Ibrahim, Mohamed El-Shinawi, Salwa Sabet, Sherif Abdelaziz Ibrahim and Mona Mostafa Mohamed
    Citation: Lipids in Health and Disease 2022 21:67
    Content type: Research Published on:

  38. The role of lipid metabolism in obesity and cancer manifestations cannot be underestimated, but whether alterations in lipid metabolism can manipulate the vasculature to promote obesity among breast cancer (BC...

    Authors: Akinkunmi Paul Okekunle, Ga-Eun Yie, Sihan Song, Zisun Kim, Hyun Jo Youn, Jihyoung Cho, Jun Won Min, Yoo Seok Kim and Jung Eun Lee
    Citation: Lipids in Health and Disease 2022 21:66
    Content type: Research Published on:

  40. Familial hypercholesterolemia (FH) is a codominant autosomal disease characterized by high low-density lipoprotein cholesterol (LDLc) and a high risk of premature cardiovascular disease (CVD). The molecular ba...

    Authors: Victoria Marco-Benedí, Ana M. Bea, Ana Cenarro, Estíbaliz Jarauta, Martín Laclaustra and Fernando Civeira
    Citation: Lipids in Health and Disease 2022 21:64
    Content type: Research Published on:

  41. To assess the long-term biological coefficient of variation within individuals (CVI) and between individuals (CVG), effect of aging and cholesterol lowering drugs on blood levels of lipids in HIV-1-infected and -...

    Authors: Najib Aziz, David W. Gjertson, Matthew J. Mimiaga, Chantel D. Azarkman, Rey Soto, Nicole Alexopoulos and Roger Detels
    Citation: Lipids in Health and Disease 2022 21:63
    Content type: Research Published on:

  42. Literature on the association between the atherogenic index of plasma (AIP) and the risk of major adverse cardiovascular events (MACEs) among non-diabetic hypertensive older adults is quite limited.

    Authors: Fei Hang, Jieruo Chen, Zefeng Wang, Keyang Zheng and Yongquan Wu
    Citation: Lipids in Health and Disease 2022 21:62
    Content type: Research Published on:

  43. It is important to identify patients at increased risk of worsening of left ventricular ejection fraction (LVEF) after a myocardial infarction (MI). We aimed to identify the association of various potential bi...

    Authors: Lina S. Silva-Bermúdez, Andrea Vargas-Villanueva, Carlos A. Sánchez-Vallejo, Ana C. Palacio, Andrés F. Buitrago and Carlos O. Mendivil
    Citation: Lipids in Health and Disease 2022 21:61
    Content type: Brief Report Published on:

  44. Trimethylamine N-oxide (TMAO)-related metabolites are associated with the pathogenesis of atherosclerotic cardiovascular disease (ASCVD) and are known to disrupt lipid metabolism. The aims of this study were t...

    Authors: Xiaowei Xiong, Jian Zhou, Qiang Fu, Xiaowei Xu, Shaobin Wei, Shenghua Yang and Buxing Chen
    Citation: Lipids in Health and Disease 2022 21:60
    Content type: Research Published on:

  45. Clinical investigations have found that there was a close association between T2DM and adverse cardiovascular events, with possible mechanisms included inflammation, apoptosis, and lipid metabolism disorders. ...

    Authors: Yufeng Mei, Zhiming Zhao, Yongnan Lyu and Yan Li
    Citation: Lipids in Health and Disease 2022 21:59
    Content type: Research Published on:

  46. The role of serum high-density lipoprotein cholesterol (HDL-c) in tumorigenesis are observed in several endocrine-related cancers. However, its role in pancreatic neuroendocrine neoplasms (PNENs) has not been ...

    Authors: Li Quan, Yongkang Liu, Wenjing Cui, Xinru Wang, Weixiao Zhang, Zhongqiu Wang, Chuangen Guo, Chao Lu, Feixiang Hu and Xiao Chen
    Citation: Lipids in Health and Disease 2022 21:58
    Content type: Research Published on:

  47. The incidence rate of metabolic-associated fatty liver disease (MAFLD) is increasing annually; however, there are still no effective methods for establishing an early diagnosis and conducting real-time tracing...

    Authors: Yuqing Zhu, Yani Ke, Yijie Hu, Kaihan Wu, Shan Liu and Jie Hu
    Citation: Lipids in Health and Disease 2022 21:57
    Content type: Review Published on:

  48. Heterozygous familial hypercholesterolemia (HeFH) due to low-density lipoprotein receptor (LDLR) mutations predisposes patients to highly elevated levels of cholesterol, and patients are at increased risk of a...

    Authors: Kasper Aalbæk Kjærgaard, Sixten Harborg, Henrik Kjærulf Jensen and Signe Borgquist
    Citation: Lipids in Health and Disease 2022 21:56
    Content type: Research Published on:

  49. The triglyceride and glucose index (TyG) and triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL-C) are substitute markers of insulin resistance (IR). In a retrospective cross-sectional study, t...

    Authors: Zhi Liu, He He, Yuzhao Dai, Lidan Yang, Shenling Liao, Zhenmei An and Shuangqing Li
    Citation: Lipids in Health and Disease 2022 21:55
    Content type: Research Published on:

  50. MicroRNAs (MiRNAs) are known to participate in preadipocyte differentiation, but the manner in which miR-146a-5p participates in this process remains unclear. This study was performed to examine the participat...

    Authors: Yifen Wang, Jie Zhang, Xueru Chu, Mengke Wang, Yongning Xin and Shousheng Liu
    Citation: Lipids in Health and Disease 2022 21:54
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X