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  1. The accumulation of misfolded proteins, encoded by genetic variants of functional genes leads to Endoplasmic Reticulum (ER) stress, which is a critical consequence in human disorders such as familial hyperchol...

    Authors: Divya Saro Varghese, Deepu Oommen, Anne John and Bassam R. Ali
    Citation: Lipids in Health and Disease 2023 22:69
    Content type: Research Published on:

  2. The epithelial lining of the gut expresses intestinal fatty-acid binding proteins (I-FABPs), which increase in circulation and in plasma concentration during intestinal damage. From the perspective of obesity,...

    Authors: Aisha Mahmood, Muhammad Naeem Faisal, Junaid Ali Khan, Humaira Muzaffar, Faqir Muhammad, Jazib Hussain, Jawad Aslam and Haseeb Anwar
    Citation: Lipids in Health and Disease 2023 22:68
    Content type: Research Published on:

  3. In contrast to guidelines related to lipid therapy in other areas, 2012 Kidney Disease Improving Global Outcomes (KDIGO) guidelines recommend conducting a lipid profile upon diagnosis of chronic kidney disease...

    Authors: Viviane Calice-Silva, Daniel Muenz, Michelle M. Y. Wong, Keith McCullough, David Charytan, Helmut Reichel, Bruce Robinson, Benedicte Stengel, Ziad A. Massy and Roberto Pecoits-Filho
    Citation: Lipids in Health and Disease 2023 22:67
    Content type: Research Published on:

  4. Myocardial infarction (MI) and post-MI-heart failure (pMIHF) are a major cause of death worldwide, however, the underlying mechanisms of pMIHF from MI are not well understood. This study sought to characterize...

    Authors: Jidong Rong, Tianmu He, Jianyong Zhang, Zhixun Bai and Bei Shi
    Citation: Lipids in Health and Disease 2023 22:66
    Content type: Research Published on:

  5. A lthough the triglyceride-glucose (TyG) index has been shown to closely correlate with cardiometabolic outcomes and predict cardiovascular events in many groups, it remains unclear whether obese status in you...

    Authors: Weihua Chen, Shan Ding, Jiabin Tu, Guitao Xiao, Kaihong Chen, Yanbin Zhang, Rongchong Huang and Ying Liao
    Citation: Lipids in Health and Disease 2023 22:65
    Content type: Research Published on:

  6. The visceral adiposity index (VAI), as a composite indictor to evaluate visceral adipose function, has been demonstrated to be correlated with atherosclerosis. The study objective was to explore the associatio...

    Authors: Weihua Zhao, Xiaotong Ma, Jiachen Ju, Yuanyuan Zhao, Xiang Wang, Shan Li, Yanling Sui and Qinjian Sun
    Citation: Lipids in Health and Disease 2023 22:64
    Content type: Research Published on:

  7. Gut microbiota are involved in the onset and development of chronic intestinal inflammation. The recently described endocannabinoidome (eCBome), a diverse and complex system of bioactive lipid mediators, has b...

    Authors: Tommaso Venneri, Giada Giorgini, Nadine Leblanc, Nicolas Flamand, Francesca Borrelli, Cristoforo Silvestri and Vincenzo Di Marzo
    Citation: Lipids in Health and Disease 2023 22:63
    Content type: Research Published on:

  8. The challenging rigorous management of hypercholesterolemia promotes referral to specialized units. This study explored the need, based on referral rate and cardiovascular (CV) risk factor control in patients ...

    Authors: Enric Serra-Planas
    Citation: Lipids in Health and Disease 2023 22:62
    Content type: Research Published on:

  9. Many commonly used drugs were evaluated as repurposed treatment options since the emergence of the COVID-19 pandemic. The benefit of lipid-lowering agents has been controversial in this regard. In this systema...

    Authors: Amirmohammad Khalaji, Amir Hossein Behnoush, Sanam Alilou, Malihe Rezaee, Soheil Peiman and Amirhossein Sahebkar
    Citation: Lipids in Health and Disease 2023 22:61
    Content type: Research Published on:

  10. Coronary artery calcification (CAC) is a potential risk marker of coronary atherosclerosis that has high specificity and sensitivity. However, the association between high-density lipoprotein cholesterol (HDL-...

    Authors: Farshad Abedi, Masoumeh Sadeghi, Navid Omidkhoda, Theodoros Kelesidis, Javad Ramezani, Sara Samadi and Amir Hooshang Mohammadpour
    Citation: Lipids in Health and Disease 2023 22:60
    Content type: Research Published on:

  12. Dyslipidaemia is key in the development of coronary heart disease (CHD) in patients with diabetes mellitus (DM). Accumulated evidence supports that diabetic nephropathy increases the mortality risk of patients...

    Authors: Xu Guo, Yujia Zhai, Chenliang Song, Zhen Mi, Jiya Peng, Jing Guo, Xianzhuo Teng and Daqing Zhang
    Citation: Lipids in Health and Disease 2023 22:58
    Content type: Research Published on:

  14. The serum lipid and immunohematological values of tuberculosis lymphadenitis (TBLN) patients is poorly documented relative to pulmonary tuberculosis (PTB) cases. Therefore, the aim of this study was to investi...

    Authors: Daniel Mekonnen, Endalkachew Nibret, Abaineh Munshea, Awoke Derbie, Yohannes Zenebe, Aimro Tadese, Tigist Birku, Endalamaw Tesfa, Mulusew Alemneh Sinishaw, Hailu Getachew, Yosef Gashaw, Gizachew Yismaw, Mihiretu M. Kebede and Baye Gelaw
    Citation: Lipids in Health and Disease 2023 22:56
    Content type: Research Published on:

  15. Psoriasis (PSO) is a skin disorder with systemic inflammation and high coronary artery disease risk. A distinct lipid phenotype occurs in psoriasis, which is characterized by high plasma triglycerides (TGs) wi...

    Authors: Alexander V. Sorokin, Nidhi Patel, Haiou Li, Christin G. Hong, Maureen Sampson, Ross O’Hagan, Elizabeth M. Florida, Heather L. Teague, Martin P. Playford, Marcus Y. Chen, Nehal N. Mehta and Alan T. Remaley
    Citation: Lipids in Health and Disease 2023 22:55
    Content type: Research Published on:

  16. Endotoxemia and sepsis induce neuroinflammation and increase the risk of neurodegenerative disorders although the mechanism by which peripheral infection leads to brain inflammation is not well understood. Whi...

    Authors: Daniel E. Radford-Smith, Abi G. Yates, Laila Rizvi, Daniel C. Anthony and Fay Probert
    Citation: Lipids in Health and Disease 2023 22:54
    Content type: Research Published on:

  17. Colorectal cancer (CRC), has a link between obesity, especially visceral fat. The body roundness index (BRI) can more accurately assess body fat and visceral fat levels. It is, however, unknown whether BRI is ...

    Authors: Wenxing Gao, Lujia Jin, Dingchang Li, Yue Zhang, Wen Zhao, Yingjie Zhao, Jingwang Gao, Lin Zhou, Peng Chen and Guanglong Dong
    Citation: Lipids in Health and Disease 2023 22:53
    Content type: Research Published on:

    The Correction to this article has been published in Lipids in Health and Disease 2023 22:59

  18. Sphingosine-1-phosphate (S1P) is a sphingolipid mediator that exerts a variety of biological functions, including immune, cardiovascular, and neurological regulation as well as tumor promotion, through high-af...

    Authors: Yuechun Zhao, Yuheng Zhang, Jiaqi Li, Ningxin Zhang, Qiubai Jin, Yuxia Qi and Ping Song
    Citation: Lipids in Health and Disease 2023 22:52
    Content type: Review Published on:

  19. The long-term excessive intake of exogenous cholesterol can lead to abnormally elevated blood lipid levels and induce cardiovascular and cerebrovascular diseases. However, the influence and relevance of exogen...

    Authors: Xichao Yu, Xue Ding, Han Feng, Yunhui Bi, Yu Li, Jinjun Shan and Huimin Bian
    Citation: Lipids in Health and Disease 2023 22:51
    Content type: Research Published on:

  20. Combined maternal and postnatal high-fat (HF) diet intake predisposes offspring to metabolic dysregulation during adulthood. As the inhibitory effects of leucine consumption on obesity and metabolic disorders ...

    Authors: Juhae Kim, Juyoung Kim and Young Hye Kwon
    Citation: Lipids in Health and Disease 2023 22:50
    Content type: Research Published on:

  21. The risk of alcoholic liver disease (ALD) is increased by excessive ethanol drinking. For the prevention of ALD, the effects of ethanol on the liver, adipose tissue, and gut are crucial. Interestingly, garlic ...

    Authors: Dhara Patel, Pooja Rathaur, Kirti Parwani, Farhin Patel, Dixa Sharma, Kaid Johar and Palash Mandal
    Citation: Lipids in Health and Disease 2023 22:49
    Content type: Research Published on:

  22. Presently, there is no consensus regarding the optimal serum uric acid (SUA) concentration for pediatric patients. Adenoid and tonsillar hypertrophy is considered to be closely associated with pediatric metabo...

    Authors: Jiating Yu, Xin Liu, Honglei Ji, Yawei Zhang, Hanqiang Zhan, Ziyin Zhang, Jianguo Wen and Zhimin Wang
    Citation: Lipids in Health and Disease 2023 22:48
    Content type: Research Published on:

  23. Insulin resistance (IR) is a major pathogenesis of nonalcoholic fatty liver disease (NAFLD). The triglyceride-glucose (TyG) index has recently gained popularity to assess IR and NAFLD due to its simplicity and...

    Authors: Sethapong Lertsakulbunlue, Mathirut Mungthin, Ram Rangsin, Anupong Kantiwong and Boonsub Sakboonyarat
    Citation: Lipids in Health and Disease 2023 22:47
    Content type: Research Published on:

  24. Up to 85% of hepatocellular carcinoma (HCC) cases in China can be attributed to infection of hepatitis B virus (HBV). Lipid metabolism performs important function in hepatocarcinogenesis of HBV–related liver c...

    Authors: Lili Zhou, Shaohuai Xia, Yaoyao Liu, Qiang Ji, Lifeng Li, Xuan Gao, Xiaodi Guo, Xin Yi and Feng Chen
    Citation: Lipids in Health and Disease 2023 22:46
    Content type: Research Published on:

  25. The tumormicroenvironment (TME) plays a key role in tumor progression. Tumor-associated macrophages (TAMs), which are natural immune cells abundantin the TME, are mainly divided into the anti-tumor M1 subtype ...

    Authors: Xuehan Qiao, Zhangmin Hu, Fen Xiong, Yufei Yang, Chen Peng, Deqiang Wang and Xiaoqin Li
    Citation: Lipids in Health and Disease 2023 22:45
    Content type: Review Published on:

  26. Nonalcoholic fatty liver disease (NAFLD), a common liver disease worldwide, can be reversed early in life with lifestyle and medical interventions. This study aimed to develop a noninvasive tool to screen NAFL...

    Authors: Hewei Peng, Junchao Zhang, Xianhua Huang, Miao Xu, Jingru Huang, Yunli Wu and Xian-E. Peng
    Citation: Lipids in Health and Disease 2023 22:44
    Content type: Research Published on:

  27. Familial chylomicronemia syndrome (FCS) is a rare autosomal recessive metabolic disorder caused by mutations in genes involved in chylomicron metabolism. On the other hand, multifactorial chylomicronemia syndr...

    Authors: Franklin Hanna Rodriguez, Jorge Mario Estrada, Henry Mauricio Arenas Quintero, Juan Patricio Nogueira and Gloria Liliana Porras-Hurtado
    Citation: Lipids in Health and Disease 2023 22:43
    Content type: Research Published on:

  28. Type 2 diabetes mellitus (T2D) and corresponding borderline states, impaired fasting glucose (IFG) and/or glucose tolerance (IGT), are associated with dyslipoproteinemia. It is important to distinguish between...

    Authors: Tina Kalbitzer, Kristina Lobenhofer, Silke Martin, Markus Beck Erlach, Werner Kremer and Hans Robert Kalbitzer
    Citation: Lipids in Health and Disease 2023 22:42
    Content type: Research Published on:

  29. Lipid accumulation product (LAP) is an index calculated by waist circumference (WC) and triglyceride (TG), which reflects lipid toxicity. This study aims to investigate the association between the LAP index an...

    Authors: Menooa Ebrahimi, Seyed Arsalan Seyedi, Seyed Ali Nabipoorashrafi, Soghra Rabizadeh, Mojdeh Sarzaeim, Amirhossein Yadegar, Fatemeh Mohammadi, Razman Arabzadeh Bahri, Peyman Pakravan, Paria Shafiekhani, Manouchehr Nakhjavani and Alireza Esteghamati
    Citation: Lipids in Health and Disease 2023 22:41
    Content type: Review Published on:

  30. Diet has a profound impact on cardiometabolic health outcomes such as obesity, blood glucose, blood lipids and blood pressure. In recent years, the gut microbiota has emerged as one of several potential key pl...

    Authors: Eline Birkeland, Sedegheh Gharagozlian, Jørgen Valeur and Anne-Marie Aas
    Citation: Lipids in Health and Disease 2023 22:40
    Content type: Review Published on:

  31. Prostate cancer (PCa), the second most prevalent solid tumor among men worldwide, has caused greatly increasing mortality in PCa patients. The effects of lipid metabolism on tumor growth have been explored, bu...

    Authors: Tianyuan Zhai, Meng Dou, Yubo Ma, Hong Wang, Fang Liu, Liandong Zhang, Tie Chong, Ziming Wang and Li Xue
    Citation: Lipids in Health and Disease 2023 22:39
    Content type: Research Published on:

  32. There is limited longitudinal evidence supporting the association between the hypertriglyceridemic-waist (HTGW) phenotype and hyperuricemia. This study aimed to examine the longitudinal relationship between hy...

    Authors: Huihui He, Suhang Wang, Tianwei Xu, Wenbin Liu, Yueping Li, Guangyu Lu and Raoping Tu
    Citation: Lipids in Health and Disease 2023 22:38
    Content type: Research Published on:

  33. Previous animal model studies have highlighted a role for cholesterol and its oxidized derivatives (oxysterols) in uterine contractile activity, however, a lipotoxic state associated with hypercholesterolemia ...

    Authors: Todd C. Rideout, Jaclyn Wallace, Xiaozhong Wen, Vanessa M. Barnabei, Kai Ling Kong and Richard W. Browne
    Citation: Lipids in Health and Disease 2023 22:37
    Content type: Brief Report Published on:

  35. The triglyceride glucose (TyG) index has been considered a new biomarker for the diagnosis of angiocardiopathy and insulin resistance. However, the association of the TyG index with subclinical left ventricula...

    Authors: Yanyan Chen, Jianfang Fu, Yi Wang, Ying Zhang, Min Shi, Cheng Wang, Mengying Li, Li Wang, Xiangyang Liu, Shengjun Ta, Liwen Liu, Zeping Li, Xiaomiao Li and Jie Zhou
    Citation: Lipids in Health and Disease 2023 22:35
    Content type: Research Published on:

  36. The miRNA-181 (miR-181) family regulates neuronal persistence during cerebral ischemia/reperfusion injury (CI/RI). Since the effect of miR-181d on CI/RI has never been studied, the current work sought to deter...

    Authors: Shengnan Li, Shaofeng Chen, Yajun Wang, Xingjuan Hu, Ying Wang, Zhaochun Wu, Shaoting Huang, Jiawen He, Fu Deng, Bin Zhao, Guoda Ma and You Li
    Citation: Lipids in Health and Disease 2023 22:34
    Content type: Research Published on:

  37. Aerobic exercise has shown beneficial effects in the prevention and treatment of non-alcoholic fatty liver disease (NAFLD). Nevertheless, the regulatory mechanism is not turely clear. Therefore, we aim to clar...

    Authors: Zongqiang Hu, Hongyu Zhang, Yiting Wang, Boyi Li, Kaiyu Liu, Jianghua Ran and Li Li
    Citation: Lipids in Health and Disease 2023 22:33
    Content type: Research Published on:

  38. The effect of body fat deposition on the kidney has received increasing attention. The Chinese visceral adiposity index (CVAI) is an important indicator of recent research. The purpose of this study was to exp...

    Authors: Yanping Xu, Xin Yi Wang, Haiping Liu, Dongzhen Jin, Xiaoxiao Song, Shengyao Wang, Xinhe Zhou, Mengte Shi, Chao Zheng and Xiaoyou Su
    Citation: Lipids in Health and Disease 2023 22:32
    Content type: Research Published on:

  39. High serum NEFA and GDF-15 are risk factors for CAD and have been linked to detrimental cardiovascular events. It has been hypothesized that hyperuricemia causes CAD via the oxidative metabolism and inflammati...

    Authors: Jingru Cheng, Yongnan Lyu, Yufeng Mei, Qian Chen, Hang Liu and Yan Li
    Citation: Lipids in Health and Disease 2023 22:31
    Content type: Research Published on:

  40. Folate is considered to be related to lipid metabolism. With the increasing numbers of folic acid fortification nations, the associations of dietary folate and serum folate with lipid profiles deserve more att...

    Authors: Yunfu Feng, Xiaohua Chen, Ying Pan and Yanting Yang
    Citation: Lipids in Health and Disease 2023 22:30
    Content type: Research Published on:

  41. Both estrogen and apolipoprotein C3 (ApoC3) play crucial roles in lipid metabolism. But the link between them remains unclear, and it is unknown whether estrogen regulates triglyceride (TG) levels via ApoC3. R...

    Authors: Jinman Li, Honglin Sun, Ying Wang, Jia Liu and Guang Wang
    Citation: Lipids in Health and Disease 2023 22:29
    Content type: Research Published on:

  43. Hypertriglyceridemia is associated with subclinical atherosclerosis and vascular inflammation even when low-density lipoprotein cholesterol levels are normal. However, few cohort studies on hypertriglyceridemi...

    Authors: Xian-dong Yu, Huihuang Huang, Yanmei Jiao, Jing Li, Xing Fan, Dawei Zhang and Fu-sheng Wang
    Citation: Lipids in Health and Disease 2023 22:27
    Content type: Research Published on:

  44. Little is known about the association between the preoperative low-density lipoprotein cholesterol (LDL-C) level and prognosis in patients with renal cell carcinoma (RCC) after nephrectomy, and its prognostic ...

    Authors: Fan Cui, Huiyu Zhou, Dingyang Lv, Jie Wen, Qian Gong, Yi Rong, Yinbo Kang, Mohan Jia and Weibing Shuang
    Citation: Lipids in Health and Disease 2023 22:26
    Content type: Research Published on:

  45. Previous studies have demonstrated the important role of fatty acid desaturase 2 (FADS2) in governing tumorigenesis and tumor metastasis. Although FADS2 is an essential regulator of fatty acid metabolism, its ...

    Authors: Enli Chen, Cong Wang, Hongwei Lv and Jing Yu
    Citation: Lipids in Health and Disease 2023 22:25
    Content type: Research Published on:

  46. Studies have reported that lipid-derived indicators are associated with type 2 diabetes (T2D) in various populations; however, it is unclear which lipid-derived indicators could effectively predict T2D risk. T...

    Authors: Linfeng He, Wenbin Zheng, Zeyu Li, Wen Kong and Tianshu Zeng
    Citation: Lipids in Health and Disease 2023 22:24
    Content type: Research Published on:

  47. Obesity is a life-threatening metabolic disorder that predisposes individuals to other diseases. In this study, the effect of nisin, a bacteriocin produced by some bacteria, on an animal model of obesity based...

    Authors: M. K. Al-Emarah, H. R. Kazerani, F. Taghizad, H. Dehghani and M. Elahi
    Citation: Lipids in Health and Disease 2023 22:23
    Content type: Research Published on:

  48. Nonalcoholic steatohepatitis (NASH) is one of the most frequent liver diseases at present, and there is no radical treatment. The consequences of a variety of ginsenoside compounds on this situation have befor...

    Authors: Xuanxin Chen, Wei Xue, Jia Zhang, Jiayi Peng and Wenxiang Huang
    Citation: Lipids in Health and Disease 2023 22:22
    Content type: Research Published on:

  49. The Clínica Universidad de Navarra-Body Adiposity Estimator (CUN-BAE) index has been recommended as an ideal indicator of body fat and exhibited significant correlation with cardiometabolic risk factors. Howev...

    Authors: Qing Peng, Zihao Feng, Zhuojian Cai, Dixing Liu, Jiana Zhong, Hejia Zhao, Xiuwei Zhang and Weikun Chen
    Citation: Lipids in Health and Disease 2023 22:21
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X