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  1. Research

    VDR Gene variation and insulin resistance related diseases

    Vitamin D status may influence the risk of Insulin resistance related diseases such as Type 2 diabetes (T2DM), metabolic syndrome (MetS), and polycystic ovarian syndrome (PCOS). Several studies have assessed v...

    Fei-fei Han, Ya-li Lv, Li-li Gong, He Liu, Zi-rui Wan and Li-hong Liu

    Lipids in Health and Disease 2017 16:157

    Published on: 19 August 2017

  2. Research

    Differential expression of osteopontin, and osteoprotegerin mRNA in epicardial adipose tissue between patients with severe coronary artery disease and aortic valvular stenosis: association with HDL subclasses

    Previous studies suggest a relationship of the epicardial adipose tissue (EAT) with progression and calcification of the atherosclerotic plaque; however, it is unknown if this tissue expresses genes that may p...

    María Luna-Luna, David Cruz-Robles, Nydia Ávila-Vanzzini, Valentín Herrera-Alarcón, Jesús Martínez-Reding, Sergio Criales-Vera, Julio Sandoval-Zárate, Jesús Vargas-Barrón, Carlos Martínez-Sánchez, Armando Roberto Tovar-Palacio, José Manuel Fragoso, Elizabeth Carreón-Torres, Gilberto Vargas-Alarcón and Óscar Pérez-Méndez

    Lipids in Health and Disease 2017 16:156

    Published on: 18 August 2017

  3. Research

    Six-month adherence to Statin use and subsequent risk of major adverse cardiovascular events (MACE) in patients discharged with acute coronary syndromes

    The evidence of adherence to statin decreasing risk of major adverse cardiovascular events (MACEs) is still lack among patients discharged with acute coronary syndrome (ACS).

    Gaoqiang Xie, Yihong Sun, Phyo Kyaw Myint, Anushka Patel, Xingzi Yang, Min Li, Xian Li, Tao Wu, Shenshen Li, Runlin Gao and Yangfeng Wu

    Lipids in Health and Disease 2017 16:155

    Published on: 15 August 2017

  4. Research

    Protective effects of orange (Citrus sinensis L.) peel aqueous extract and hesperidin on oxidative stress and peptic ulcer induced by alcohol in rat

    Massive alcohol drinking can lead to gastric ulcer. In the present study we investigated the gastroprotective effect of Citrus sinensis peel aqueous extract (CSPE) and Hesperidin (H) in ethanol (EtOH) induced oxi...

    Slimen Selmi, Kais Rtibi, Dhekra Grami, Hichem Sebai and Lamjed Marzouki

    Lipids in Health and Disease 2017 16:152

    Published on: 14 August 2017

  5. Research

    Cardamom powder supplementation prevents obesity, improves glucose intolerance, inflammation and oxidative stress in liver of high carbohydrate high fat diet induced obese rats

    Cardamom is a well-known spice in Indian subcontinent, used in culinary and traditional medicine practices since ancient times. The current investigation was untaken to evaluate the potential benefit of cardam...

    Md Mizanur Rahman, Mohammad Nazmul Alam, Anayt Ulla, Farzana Akther Sumi, Nusrat Subhan, Trisha Khan, Bishwajit Sikder, Hemayet Hossain, Hasan Mahmud Reza and Md Ashraful Alam

    Lipids in Health and Disease 2017 16:151

    Published on: 14 August 2017

  6. Research

    Liquid chromatography mass spectrometry-based profiling of phosphatidylcholine and phosphatidylethanolamine in the plasma and liver of acetaminophen-induced liver injured mice

    Acetaminophen (APAP) overdose is one of the most common causes of acute liver failure in many countries. The aim of the study was to describe the profiling of phosphatidylcholine (PC) and phosphatidylethanolam...

    Ya-Nan Ming, Jing-Yi Zhang, Xiao-Lin Wang, Chun-Min Li, Si-Cong Ma, Zheng-Yang Wang, Xiao-Lin Liu, Xiao-Bo Li and Yi-Min Mao

    Lipids in Health and Disease 2017 16:153

    Published on: 14 August 2017

  7. Research

    Decreased circulating dihomo-gamma-linolenic acid levels are associated with total mortality in patients with acute cardiovascular disease and acute decompensated heart failure

    Polyunsaturated fatty acids (PUFAs) have important roles in the pathogenesis of cardiovascular diseases. However, the clinical significance of omega-6 PUFAs in acute cardiovascular disease remains unknown.

    Shohei Ouchi, Tetsuro Miyazaki, Kazunori Shimada, Yurina Sugita, Megumi Shimizu, Azusa Murata, Takao Kato, Tatsuro Aikawa, Shoko Suda, Tomoyuki Shiozawa, Masaru Hiki, Shuhei Takahashi, Takatoshi Kasai, Katsumi Miyauchi and Hiroyuki Daida

    Lipids in Health and Disease 2017 16:150

    Published on: 14 August 2017

  8. Review

    Omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid and their mechanisms of action on apolipoprotein B-containing lipoproteins in humans: a review

    Epidemiological and genetic studies suggest that elevated triglyceride (TG)-rich lipoprotein levels in the circulation increase the risk of cardiovascular disease. Prescription formulations of omega-3 fatty ac...

    Jan Oscarsson and Eva Hurt-Camejo

    Lipids in Health and Disease 2017 16:149

    Published on: 10 August 2017

  9. Research

    Insulin resistance and associated factors among HIV-infected patients in sub-Saharan Africa: a cross sectional study from Cameroon

    Little is known on the magnitude and correlates of insulin resistance in HIV-infected people in Africa. We determined the prevalence of insulin resistance and investigated associated factors in HIV-infected ad...

    Steve Raoul Ngongang Noumegni, Jobert Richie Nansseu, Vicky Jocelyne Moor Ama, Jean Joel Bigna, Felix Kembe Assah, Magellan Guewo-Fokeng, Steve Leumi, Jean-Claude Katte, Mesmin Dehayem, Andre Pascal Kengne and Eugene Sobngwi

    Lipids in Health and Disease 2017 16:148

    Published on: 10 August 2017

  10. Research

    The relationship of plasma Trans fatty acids with dietary inflammatory index among US adults

    It has been suggested that trans fatty acids (TFAs) play an important role in cardiovascular diseases. We investigated the association between plasma TFAs and the dietary inflammatory index (DII) ™ in US adults.

    Mohsen Mazidi, Hong-kai Gao, Nitin Shivappa, Michael D. Wirth, James R Hebert and Andre Pascal Kengne

    Lipids in Health and Disease 2017 16:147

    Published on: 4 August 2017

  11. Research

    Citrus lemon essential oil: chemical composition, antioxidant and antimicrobial activities with its preservative effect against Listeria monocytogenes inoculated in minced beef meat

    Lemon (Citrus limon) is a flowing plant belonging to the Rutaceae family. Citrus plants constitute one of the main valuable sources of essential oil used in foods and medicinal purposes.

    Anis Ben Hsouna, Nihed Ben Halima, Slim Smaoui and Naceur Hamdi

    Lipids in Health and Disease 2017 16:146

    Published on: 3 August 2017

  12. Research

    Metabolomics study of the therapeutic mechanism of Schisandra Chinensis lignans in diet-induced hyperlipidemia mice

    Schisandra, a globally distributed plant, has been widely applied for the treatment of diseases such as hyperlipidemia, fatty liver and obesity in China. In the present work, a rapid resolution liquid chromato...

    Jing-Hui Sun, Xu Liu, Li-Xin Cong, He Li, Cheng-Yi Zhang, Jian-Guang Chen and Chun-Mei Wang

    Lipids in Health and Disease 2017 16:145

    Published on: 1 August 2017

  13. Research

    Isolated hypercholesterolemia leads to steatosis in the liver without affecting the pancreas

    Lipid accumulation in the liver and pancreas is primarily caused by combined hyperlipidemia. However, the effect of isolated hypercholesterolemia without hypertriglyceridemia is not fully described. Therefore,...

    Csaba Csonka, Tamás Baranyai, László Tiszlavicz, Hedvig Fébel, Gergő Szűcs, Zoltán V. Varga, Márta Sárközy, László G. Puskás, Otilia Antal, Andrea Siska, Imre Földesi, Péter Ferdinandy, László Czakó and Tamás Csont

    Lipids in Health and Disease 2017 16:144

    Published on: 27 July 2017

  14. Research

    Visceral fat mass: is it the link between uric acid and diabetes risk?

    Uric acid (UA) has been suggested as a novel risk factor for diabetes. However, its definite role in this prevalent disease is still the subject of much discussion because it is always accompanied with other m...

    Neda Seyed-Sadjadi, Jade Berg, Ayse A. Bilgin and Ross Grant

    Lipids in Health and Disease 2017 16:142

    Published on: 24 July 2017

  15. Research

    Efficacy and safety of proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors, alirocumab and evolocumab, a post-commercialization study

    Efficacy-safety of proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors, alirocumab (ALI) and evolocumab (EVO), have previously been evaluated through controlled clinical trials with selective pati...

    Joshua Choi, Amir M Khan, Michael Jarmin, Naila Goldenberg, Charles J Glueck and Ping Wang

    Lipids in Health and Disease 2017 16:141

    Published on: 24 July 2017

  16. Research

    Acute changes in blood lipid profiles and metabolic risk factors in collegiate elite taekwondo athletes after short-term de-training: a prospective insight for athletic health management

    This study used a short-term de-training model to mimic the physiological weight changes during the early retirement stage in Taekwondo (TKD) athletes. This study investigates whether the negative changes in b...

    Yu-Chi Sung, Yi-Hung Liao, Chung-Yu Chen, Yu-Liang Chen and Chun-Chung Chou

    Lipids in Health and Disease 2017 16:143

    Published on: 24 July 2017

  17. Research

    Association between serum osteocalcin and glucose/lipid metabolism in Chinese Han and Uygur populations with type 2 diabetes mellitus in Xinjiang: two cross-sectional studies

    Recent studies have shown osteocalcin (OC) plays an important role in regulating glucose and lipid metabolism. Thus, the aim of this study was to investigate the association of OC with glucose and lipid metabo...

    Yuan Chen, Qiang Zhao, Guoli Du and Yancheng Xu

    Lipids in Health and Disease 2017 16:139

    Published on: 21 July 2017

  18. Research

    Lysophosphatidic acid plasma concentrations in healthy subjects: circadian rhythm and associations with demographic, anthropometric and biochemical parameters

    Lysophosphatidic acid (LPA) is a bioactive lipid with a wide biological activity. Previous studies have shown its potential usefulness as a diagnostic marker for ovarian cancer. The aim of the study was to inv...

    Anna Michalczyk, Marta Budkowska, Barbara Dołęgowska, Dariusz Chlubek and Krzysztof Safranow

    Lipids in Health and Disease 2017 16:140

    Published on: 21 July 2017

  19. Research

    Identification and characterization of single nucleotide polymorphism markers in FADS2 gene associated with olive oil fatty acids composition

    Genotyping of the FAD2.1 and FAD2.3 polymorphisms in the fatty acid desaturase 2 gene (FADS2) shows that they are associated with the fatty acids composition of olive oil samples. However, these associations requ...

    Rayda Ben Ayed, Karim Ennouri, Hajer Ben Hlima, Slim Smaoui, Mohsen Hanana, Rim Mzid, Sezai Ercişli and Ahmed Rebai

    Lipids in Health and Disease 2017 16:138

    Published on: 12 July 2017

  20. Research

    15-oxoeicosatetraenoic acid mediates monocyte adhesion to endothelial cell

    A great number of studies reported that 12/15-lipoxygenase (12/15-LO) played an important role in atherosclerosis. And its arachidonic acid(AA) metabolite, 15(S)-hydroperoxy-5,8,11,13-(Z,Z,Z,E)-eicosatetraenoi...

    Guohua Ma, Bing Pan, Sufen Ren, Caixia Guo, Yansong Guo, Lixin Wei, Lemin Zheng and Buxing Chen

    Lipids in Health and Disease 2017 16:137

    Published on: 12 July 2017

  21. Research

    Dietary supplementation of α-linolenic acid induced conversion of n-3 LCPUFAs and reduced prostate cancer growth in a mouse model

    α-linolenic acid (ALA) is an n-3 polyunsaturated fatty acid (PUFA) and the substrate for long-chain n-3 PUFAs. The beneficial effects of ALA on chronic diseases are still in dispute, unlike those of eicosapent...

    Jingjing Li, Zhennan Gu, Yong Pan, Shunhe Wang, Haiqin Chen, Hao Zhang, Wei Chen and Yong Q. Chen

    Lipids in Health and Disease 2017 16:136

    Published on: 11 July 2017

  22. Research

    Intracellular high cholesterol content disorders the clock genes, apoptosis-related genes and fibrinolytic-related genes rhythmic expressions in human plaque-derived vascular smooth muscle cells

    The clock genes are involved in regulating cardiovascular functions, and their expression disorders would lead to circadian rhythm disruptions of clock-controlled genes (CCGs), resulting in atherosclerotic pla...

    Changpo Lin, Xiao Tang, Lirong Xu, Ruizhe Qian, Zhenyu Shi, Lixin Wang, Tingting Cai, Dong Yan, Weiguo Fu and Daqiao Guo

    Lipids in Health and Disease 2017 16:135

    Published on: 10 July 2017

  23. Research

    Baccaurea angulata fruit juice reduces atherosclerotic lesions in diet-induced Hypercholesterolemic rabbits

    Atherosclerosis is the most common disease of large and medium-sized arteries linked to oxidative stress, dyslipidemia as well as chronic inflammation. The aim of this study was to evaluate the potential healt...

    Muhammad Ibrahim, Idris Adewale Ahmed, Maryam Abimbola Mikail, Afeez Adekunle Ishola, Samsul Draman, Muhammad Lokman Md Isa and Afzan Mat Yusof

    Lipids in Health and Disease 2017 16:134

    Published on: 7 July 2017

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