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  1. The present study was designed to test the hypothesis that in the liver, excessive fat accumulation impairs cholesterol metabolism mainly by altering the low-density lipoprotein-receptor (LDL-R) pathway.

    Authors: Roxane St-Amand, Émilienne T. Ngo Sock, Samantha Quinn, Jean-Marc Lavoie and David H. St-Pierre

    Citation: Lipids in Health and Disease 2020 19:192

    Content type: Research

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  2. Niacin has modest but overall favorable effects on plasma lipids by increasing high density lipoprotein cholesterol (HDL-C) and lowering triglycerides. Clinical trials, however, evaluating niacin therapy for p...

    Authors: Scott M. Gordon, Marcelo J. Amar, Kianoush Jeiran, Michael Stagliano, Emma Staller, Martin P. Playford, Nehal N. Mehta, Tomas Vaisar and Alan T. Remaley

    Citation: Lipids in Health and Disease 2020 19:190

    Content type: Research

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  3. Cardiac Ca2+/calmodulin-dependent protein kinase II (CaMKII) activation plays a critical role in cardiomyocyte (CM) apoptosis and arrhythmia. Functional ATP-sensitive potassium (KATP) channels are essential for c...

    Authors: Yanzhuo Ma, Nancy Cheng, Junping Sun, Jonathan Xuhai Lu, Shahrzad Abbasi, Geru Wu, An-Sheng Lee, Tatsuya Sawamura, Jie Cheng, Chu-Huang Chen and Yutao Xi

    Citation: Lipids in Health and Disease 2020 19:189

    Content type: Research

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  4. Obesity and adipose tissue expansion is characterized by a chronic state of systemic inflammation that contributes to disease. The neuropeptide, oxytocin, working through its receptor has been shown to attenua...

    Authors: Angela Szeto, Monia Cecati, Raisa Ahmed, Philip M. McCabe and Armando J. Mendez

    Citation: Lipids in Health and Disease 2020 19:188

    Content type: Research

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  5. HMGCR, SCAP, SREBF1, SREBF2 and TBL2 are well-known genes that are involved in the process of lipid metabolism. However, it is not known whether epigenetic changes of these genes are associated with lipid metabol...

    Authors: Yang Li, Shuai Liu, Yong-Tao Wang, Han Min, Dilare Adi, Xiao-Mei Li, Yi-Ning Yang, Zhen yan Fu and Yi-Tong Ma

    Citation: Lipids in Health and Disease 2020 19:186

    Content type: Research

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  6. To investigate whether atherogenic index of plasma (AIP) at diagnosis is associated with the occurrence of cerebrovascular accident (CVA) or coronary artery disease (CAD) in antineutrophil cytoplasmic antibody...

    Authors: Sung Soo Ahn, Lucy Eunju Lee, Jung Yoon Pyo, Jason Jungsik Song, Yong-Beom Park and Sang-Won Lee

    Citation: Lipids in Health and Disease 2020 19:184

    Content type: Research

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  7. The potential cardioprotective benefits of olive oil (OO) and canola oil (CO) consumption have been shown in some studies. The present study compared the effects of CO and OO on plasma lipids, some inflammator...

    Authors: Nafiseh Khandouzi, Ali Zahedmehr and Javad Nasrollahzadeh

    Citation: Lipids in Health and Disease 2020 19:183

    Content type: Research

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  8. Triglyceride glucose (TyG) index is a reliable marker of insulin resistance, which is linked to obstructive sleep apnea (OSA). However, the relationship between TyG index and OSA has not been adequately assess...

    Authors: Hyeon Hui Kang, Sei Won Kim and Sang Haak Lee

    Citation: Lipids in Health and Disease 2020 19:182

    Content type: Research

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  9. Cytochrome P450 (CYPs) participate in the mechanisms of cardiovascular disease. The purpose of this research was to evaluate the contributions of CYP24A1 variants to coronary heart disease (CHD) among the Chinese...

    Authors: Peng Qian, Xuanchao Cao, Xianjing Xu, Mingqin Duan, Qian Zhang and Gairong Huang

    Citation: Lipids in Health and Disease 2020 19:181

    Content type: Research

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  10. Quercetin was reported to be crucial for a broad range of activities, including attenuating inflammation, platelet aggregation, capillary permeability, and lipid peroxidation. However, the effect of quercetin ...

    Authors: Xia Sun, Shuping Zhang and Haitao Song

    Citation: Lipids in Health and Disease 2020 19:180

    Content type: Research

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  11. It is uncertain whether estimated remnant-like particle cholesterol (RLP-C) could predict residual risk in patients with different glycometabolic status. This study aimed to evaluate the relationship between e...

    Authors: Qi Zhao, Ting-Yu Zhang, Yu-Jing Cheng, Yue Ma, Ying-Kai Xu, Jia-Qi Yang and Yu-Jie Zhou

    Citation: Lipids in Health and Disease 2020 19:179

    Content type: Research

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  12. Although the human chromosome 19q13 loci are reported to be associated with hyper-LDL-cholesterolemia, the haplotype of single nucleotide polymorphism (SNP) has not been studied. Therefore, the association of ...

    Authors: Sunmin Park and Suna Kang

    Citation: Lipids in Health and Disease 2020 19:178

    Content type: Research

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  13. Intima-media thickness (IMT) and small dense low-density lipoprotein cholesterol (sdLDL-C) have been reported to be related to atherosclerosis and stroke. This study is trying to explore the association betwee...

    Authors: Peiyang Zhou, Yan Shen, Lingyun Wang, Zhihua Cao, Wenmin Feng, Jincheng Liu, Lijun Wang, Peng Meng, Jinbo Yang, Wang-Yang Xu and Ping Gao

    Citation: Lipids in Health and Disease 2020 19:177

    Content type: Research

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  14. Lipid disorder is one of the most important risk factors for chronic diseases. Identifying the factors affecting the development of lipid disorders helps reduce chronic diseases, especially Chronic Heart Disea...

    Authors: Mansour Rezaei, Negin Fakhri, Yahya Pasdar, Mehdi Moradinazar and Farid Najafi

    Citation: Lipids in Health and Disease 2020 19:176

    Content type: Research

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  15. Low high-density lipoprotein cholesterol (HDL-C) disease with unknown etiology has a high prevalence in the Xinjiang Kazak population. In this study, long noncoding RNAs (lncRNAs) that might play a role in low...

    Authors: Xinping Wang, Shuxia Guo, Yunhua Hu, Heng Guo, Xianghui Zhang, Yizhong Yan, Jiaolong Ma, Yu Li, Haixia Wang, Jia He and Rulin Ma

    Citation: Lipids in Health and Disease 2020 19:175

    Content type: Research

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  16. Maternal obesity is an emerging problem in the modern world. Growing evidence suggests that intrauterine high-fat (HF) exposure may predispose progeny to subsequent metabolic challenges. Progeny born to mother...

    Authors: Ta-Yu Liu, Hong-Ren Yu, Ching-Chou Tsai, Li-Tung Huang, Chih-Cheng Chen, Jium-Ming Sheen, Mao-Meng Tiao, You-Lin Tain, I-Chun Lin, Yun-Ju Lai, Yu-Ju Lin and Te-Yao Hsu

    Citation: Lipids in Health and Disease 2020 19:174

    Content type: Research

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  17. Low-density lipoprotein cholesterol (LDL-c) has been proven to be a risk factor for atherosclerotic cardiovascular disease (CVD), while lipoprotein (a) (Lp(a)) is a residual risk factor for CVD, even though LD...

    Authors: Xiangming Hu, Xing Yang, Xida Li, Demou Luo, Yingling Zhou and Haojian Dong

    Citation: Lipids in Health and Disease 2020 19:173

    Content type: Research

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  18. Differential effects of individual saturated fatty acids (SFAs), particularly stearic acid (C18:0), relative to the shorter-chain SFAs have drawn interest for more accurate nutritional guidelines. However, spe...

    Authors: Liqiang Wang, Fei Xu, Zhenfeng Song, Dan Han, Jingyi Zhang, Linjun Chen and Lixin Na

    Citation: Lipids in Health and Disease 2020 19:172

    Content type: Research

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  19. Senile pruritus is common, yet its etiology remains unknown. Aging-associated skin barrier defects and skin surface lipid (SSL) alterations have been postulated to play important roles in its occurrence. In th...

    Authors: Xiaolei Ma, Lulu Lu, Zheng Zhao, Mingru Cai, Na Gao and Gangwen Han

    Citation: Lipids in Health and Disease 2020 19:171

    Content type: Research

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  20. The term arterial stiffness (ArSt) describes structural changes in arterial wall related to the loss of elasticity and is known as an independent predictor of cardiovascular diseases (CVD). The evidence relati...

    Authors: Iuliia Pavlovska, Sarka Kunzova, Juraj Jakubik, Jana Hruskova, Maria Skladana, Irma Magaly Rivas-Serna, Jose R. Medina-Inojosa, Francisco Lopez-Jimenez, Robert Vysoky, Yonas E. Geda, Gorazd B. Stokin and Juan P. González-Rivas

    Citation: Lipids in Health and Disease 2020 19:170

    Content type: Research

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  21. Familial hypercholesterolemia (FH) increases the risk of atherosclerosis in children and adults. Atherosclerotic cardiovascular disease in young patients FH is usually subclinical but recognition of children w...

    Authors: Michał Podgórski, Katarzyna Szatko, Małgorzata Stańczyk, Monika Pawlak-Bratkowska, Agnieszka Konopka, Ewa Starostecka, Marcin Tkaczyk, Sebastian Góreczny, Lena Rutkowska, Agnieszka Gach, Maciej Łukaszewski, Piotr Grzelak and Maciej Banach

    Citation: Lipids in Health and Disease 2020 19:169

    Content type: Research

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  22. Evidence on the association between the non-high-density lipoprotein cholesterol (non-HDLc)-to-high-density lipoprotein cholesterol (HDLc) ratio (non-HDLc/HDLc) and carotid plaques is still limited. This study...

    Authors: Yan Liu, Zhenwen Zhang, Binlan Xia, Liping Wang, Hengzhong Zhang, Yan Zhu, Chao Liu and Bin Song

    Citation: Lipids in Health and Disease 2020 19:168

    Content type: Research

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  23. Many patients suffering from exercise-induced asthma (EIA) have normal lung function at rest and show symptoms and a decline in FEV1 when they do sports or during exercise-challenge. It has been described that lo...

    Authors: M. Dreßler, D. Fussbroich, L. Böhler, E. Herrmann, N. Benker, M. Tytyk, J. Schulze, R. Schubert, C. Beermann and S. Zielen

    Citation: Lipids in Health and Disease 2020 19:167

    Content type: Research

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  24. Rubus coreanus (R. coreanus) possesses properties that may decrease cholesterol levels.

    Authors: Jung Min Cho, Jisuk Chae, Sa Rang Jeong, Min Jung Moon, Ki-Chan Ha, Sunoh Kim and Jong Ho Lee

    Citation: Lipids in Health and Disease 2020 19:166

    Content type: Research

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  25. Dietary fish oil (DFO) has been identified as a micronutrient supplement with the potential to improve musculoskeletal health in old age. Few data are available for effects of DFO on muscle contractility, desp...

    Authors: David W. Russ, Kalina Dimova, Emily Morris, Marguerite Pacheco, Sean M. Garvey and Stylianos P. Scordilis

    Citation: Lipids in Health and Disease 2020 19:165

    Content type: Research

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  26. Obesity exhibits a correlation with metabolic inflammation and endoplasmic reticulum stress, promoting the progression of metabolic disease such as diabetes, hyperlipidemia, hyperuricemia and so on. Adipose ti...

    Authors: Yunjia Li, Ke Yun and Runqing Mu

    Citation: Lipids in Health and Disease 2020 19:164

    Content type: Review

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  27. Coronary heart disease (CHD) is one of the leading causes of death worldwide. Percutaneous coronary intervention (PCI) has been an important technology for the treatment of CHD. Blood lipid management is criti...

    Authors: Weiyu Qiu, Jiali Chen, Xianzhen Huang and Jun Guo

    Citation: Lipids in Health and Disease 2020 19:163

    Content type: Research

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  28. Dietary n− 3 polyunsaturated fatty acids (PUFAs) have a role in preventing cardiovascular and hepatic diseases. However, their effects might differ significantly depending on individual dietary patterns. The aim ...

    Authors: Silvia Godea (Lupei), Diana Ciubotariu, Mihai Danciu, Raoul Vasile Lupușoru, Cristina Mihaela Ghiciuc, Irina Cernescu, Nicolae Gheţu, Mihai Lupei and Cătălina Elena Lupușoru

    Citation: Lipids in Health and Disease 2020 19:162

    Content type: Research

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  29. Higher levels of anandamide (AEA) and 2-arachidonoylglycerol (2-AG), the main arachidonic acid-derived endocannabinoids, are frequently reported in overweight and obese individuals. Recently, endocannabinoids ...

    Authors: Neda Lotfi Yagin, Samaneh Hajjarzadeh, Soghra Aliasgharzadeh, Fereshteh Aliasgari and Reza Mahdavi

    Citation: Lipids in Health and Disease 2020 19:161

    Content type: Research

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  30. Many studies indicate that gallstone formation has genetic components. The abnormal expression of lipid-related genes could be the basis for particular forms of cholesterol gallstone disease. The aim of this s...

    Authors: Ning Fan, Ke Meng, Yuqing Zhang, Yong Hu, Donghua Li, Qiaoying Gao, Jianhua Wang, Yanning Li, Shangwei Wu and Yunfeng Cui

    Citation: Lipids in Health and Disease 2020 19:158

    Content type: Research

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  31. Dyslipidemia is a well-known risk factor for cardiovascular disease (CVD). Recently, atherogenic index of plasma (AIP) has been proposed as a novel predictive marker for CVD, and few cross sectional studies ha...

    Authors: Ji Sun Nam, Min Kyung Kim, Joo Young Nam, Kahui Park, Shinae Kang, Chul Woo Ahn and Jong Suk Park

    Citation: Lipids in Health and Disease 2020 19:157

    Content type: Research

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  32. The prevalence of type 2 diabetes, obesity and their various comorbidities have continued to rise. In skeletal muscle lipotoxicity is well known to be a contributor to the development of insulin resistance. He...

    Authors: Amy Botta, Kazaros Elizbaryan, Parastoo Tashakorinia, Nhat Hung Lam and Gary Sweeney

    Citation: Lipids in Health and Disease 2020 19:156

    Content type: Research

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  33. Previous studies have suggested that abnormal sleep duration is associated with increased risk of metabolic syndrome (MetS). However, evidence on the association of sleep duration with stroke, myocardial infar...

    Authors: Yingnan YE, Linxi ZHANG, Anping WANG, Yuxia Wang, Shiqing WANG, Guang NING and Yiming MU

    Citation: Lipids in Health and Disease 2020 19:155

    Content type: Research

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  34. A study has been performed in overweight and obese subjects to assess the effects of adiposity and inflammation indicators on dysmetabolic biomarkers via red cell distribution width (RDW) and mean corpuscular ...

    Authors: Mariangela Rondanelli, Simone Perna, Tariq A. Alalwan, Roberta Cazzola, Clara Gasparri, Vittoria Infantino, Federica Perdoni, Giancarlo Iannello, Daniele Pepe and Davide Guido

    Citation: Lipids in Health and Disease 2020 19:154

    Content type: Research

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  35. The lipoprotein insulin resistance (LPIR) score was shown to predict insulin resistance (IR) and type 2 diabetes (T2D) in healthy adults. However, the molecular basis underlying the LPIR utility for classifica...

    Authors: Minoo Bagheri, Hemant K. Tiwari, Anarina L. Murillo, Rafet Al-Tobasei, Donna K. Arnett, Tobias Kind, Dinesh Kumar Barupal, Sili Fan, Oliver Fiehn, Jeff O’connell, May Montasser, Stella Aslibekyan and Marguerite R. Irvin

    Citation: Lipids in Health and Disease 2020 19:153

    Content type: Research

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  36. The present study aims to estimate whether high-density lipoprotein cholesterol (HDL-C) is correlated with cardiovascular events (CVEs) and cardiovascular mortality (CVM) in a large sample of the general popul...

    Authors: Shasha Yu, Xiaofan Guo, Guang Xiao Li, Hongmei Yang, Liqiang Zheng and Yingxian Sun

    Citation: Lipids in Health and Disease 2020 19:152

    Content type: Research

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  37. Coronary artery stenosis induces heart diseases including acute coronary syndrome (ACS). Some studies reported the ceramide species are associated with the ACS and major adverse cardia and cerebrovascular even...

    Authors: Chenchen Tu, Lan Xie, Zhenjie Wang, Lili Zhang, Hongmei Wu, Wei Ni, Caixia Li, Lin Li and Yong Zeng

    Citation: Lipids in Health and Disease 2020 19:151

    Content type: Research

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  38. Inflammation and oxidative stress play predominant roles in the initiation and progression of ischaemia/reperfusion (I/R) injury, with nuclear factor kappa B (NF-κB) serving as a crucial mediator. Overexpressi...

    Authors: Min Han, Xiao-Cui Chen, Ming-Hui Sun, Min-Tao Gai, Yi-Ning Yang, Xiao-Ming Gao, Xiang Ma, Bang-Dang Chen and Yi-Tong Ma

    Citation: Lipids in Health and Disease 2020 19:150

    Content type: Research

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  39. The mechanism between smoking and coronary artery disease (CAD) remains unclear. It is likely that lipid (including triglycerides (TG), total cholesterol (TC), low density lipoprotein-cholesterol (LDL-C), high...

    Authors: Wenjing Song, Jieqiong Guan, Pan He, Siyu Fan, Hong Zhi and Lina Wang

    Citation: Lipids in Health and Disease 2020 19:149

    Content type: Research

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  40. The atherogenic index of plasma (AIP) is elevated in fatty liver disease, but its value in non-obese people with non-alcoholic fatty liver disease (NAFLD) is unclear. This study aimed to investigate the relati...

    Authors: Bu-yuan Dong, Yu-qing Mao, Zheng-yang Li and Fu-jun Yu

    Citation: Lipids in Health and Disease 2020 19:148

    Content type: Research

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  41. Plasma concentration of low-density lipoprotein cholesterol (LDL-C) is causally related to the risk of arteriosclerotic events. Whether ATP-sensitive potassium channels (KATP) genetic variants predict increased L...

    Authors: Cheng Liu, Tianwang Guan, Yanxian Lai, Jieming Zhu, Jian Kuang and Yan Shen

    Citation: Lipids in Health and Disease 2020 19:147

    Content type: Research

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  42. Dyslipidaemia and male sex are associated with gallbladder polyp (GBP) formation. However, the potential relation between the non-high-density lipoprotein-cholesterol-to-high-density lipoprotein-cholesterol (n...

    Authors: Xiaofang Zhao, Huabo Zheng, Shengshuai Shan, Kun Wang, Meng Zhang, Songpu Xie and Chengyun Liu

    Citation: Lipids in Health and Disease 2020 19:146

    Content type: Research

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  43. Fasting plasma glucose (FPG) is an easily quantifiable and inexpensive metabolic marker, which is often used to assess cardiovascular disease and diabetes. However, there have been limited studies on the assoc...

    Authors: Yang Zou, Meng Yu and Guotai Sheng

    Citation: Lipids in Health and Disease 2020 19:145

    Content type: Research

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  44. Amaranth seed oil (ASO) and rapeseed oil (RSO) are functional foods that display antioxidant and hepatoprotective properties. These oils are also known to lower glucose and cholesterol levels. The current stud...

    Authors: Małgorzata Moszak, Agnieszka Zawada, Aldona Juchacz, Marian Grzymisławski and Paweł Bogdański

    Citation: Lipids in Health and Disease 2020 19:143

    Content type: Research

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  45. The discordance of the low-density lipoprotein cholesterol-to-high-density lipoprotein cholesterol (LDL-C/HDL-C) ratio with alterative lipid parameters may explain the inconsistent association of CIMT with the...

    Authors: Yanmei Lou, Xue Li, Liming Cao, Pei Qin, Jing Shi, Yanyan Zhang, Changyi Wang, Jianping Ma, Li Wang, Xiaolin Peng, Hongen Chen, Shan Xu, Fulan Hu, Yashuang Zhao and Ping Zhao

    Citation: Lipids in Health and Disease 2020 19:141

    Content type: Research

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