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  1. Content type: Research

    Lowering insulin resistance and dyslipidaemia may not only enhance glycaemic control but also preserve the β-cell function, reducing the overall risk of developing type 2 diabetes (T2D). The current study was ...

    Authors: Rohith N. Thota, Shamasunder H. Acharya and Manohar L. Garg

    Citation: Lipids in Health and Disease 2019 18:31

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  2. Content type: Review

    Altered metabolism of lipids is currently considered a hallmark characteristic of many malignancies, including colorectal cancer (CRC). Lipids are a large group of metabolites that differ in terms of their fat...

    Authors: Alicja Pakiet, Jarosław Kobiela, Piotr Stepnowski, Tomasz Sledzinski and Adriana Mika

    Citation: Lipids in Health and Disease 2019 18:29

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  3. Content type: Review

    Brain is a vital organ of the human body which performs very important functions such as analysis, processing, coordination, and execution of electrical signals. For this purpose, it depends on a complex netwo...

    Authors: Ghulam Hussain, Jing Wang, Azhar Rasul, Haseeb Anwar, Ali Imran, Muhammad Qasim, Shamaila Zafar, Syed Kashif Shahid Kamran, Aroona Razzaq, Nimra Aziz, Waseem Ahmad, Asghar Shabbir, Javed Iqbal, Shahid Mahmood Baig and Tao Sun

    Citation: Lipids in Health and Disease 2019 18:26

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  4. Content type: Research

    Genetic variation in the genes ALOX5 (arachidonate 5-lipoxygenase), ALOX5AP (arachidonate 5-lipoxygenase-activating protein) and LTA4H (leukotriene A4 hydrolase) has previously been shown to contribute to the ...

    Authors: Yilan Li, Xueming Xu, Dandan Zhang, Wei Cheng, Yanan Zhang, Bo Yu and Yao Zhang

    Citation: Lipids in Health and Disease 2019 18:25

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  5. Content type: Research

    N-acetylneuraminic acid (NANA) is the major form of sialic acid in mammals, and the plasma NANA level is increased in patients with cardiovascular diseases. Exogenous supplement of NANA has been demonstrated t...

    Authors: Pengbo Hou, Shumei Hu, Jin Wang, Zixun Yang, Jiayu Yin, Guanghai Zhou and Shoudong Guo

    Citation: Lipids in Health and Disease 2019 18:24

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  6. Content type: Review

    Elevated levels of fetuin-A are associated with increased risks of metabolic syndrome, type 2 diabetes and nonalcoholic fatty liver disease. This meta-analysis investigated whether exercise interventions can r...

    Authors: Robinson Ramírez-Vélez, Antonio García-Hermoso, Anthony C. Hackney and Mikel Izquierdo

    Citation: Lipids in Health and Disease 2019 18:23

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  7. Content type: Research

    The role of triglyceride (TG) in secondary prevention of patients with coronary artery disease (CAD) was debated. In the present study, we assessed the association between admission TG levels and long-term mor...

    Authors: Tian-li Xia, Yi-ming Li, Fang-yang Huang, Hua Chai, Bao-tao Huang, Qiao Li, Zhen-gang Zhao, Yan-biao Liao, Zhi-liang Zuo, Yong Peng, Mao Chen and De-jia Huang

    Citation: Lipids in Health and Disease 2019 18:21

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  8. Content type: Research

    The aim of this study was to analyse the differences in the phospholipid composition of very low density (VLDL), low density (LDL) and high density lipoprotein (HDL) monolayers in pregnant lean and obese women.

    Authors: Sebastian Rauschert, Antonio Gázquez, Olaf Uhl, Franca F. Kirchberg, Hans Demmelmair, María Ruíz-Palacios, María T. Prieto-Sánchez, José E. Blanco-Carnero, Anibal Nieto, Elvira Larqué and Berthold Koletzko

    Citation: Lipids in Health and Disease 2019 18:20

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  9. Content type: Research

    Prenatal dexamethasone treatment has been shown to enhance the susceptibility of offspring to postnatal high-fat (HF) diet-induced programmed obesity. We investigated the metabolic phenotypes, nutrient-sensing...

    Authors: Ching-Chou Tsai, Mao-Meng Tiao, Jiunn-Ming Sheen, Li-Tung Huang, You-Lin Tain, I-Chun Lin, Yu-Ju Lin, Yun-Ju Lai, Chih-Cheng Chen, Kow-Aung Chang and Hong-Ren Yu

    Citation: Lipids in Health and Disease 2019 18:19

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  10. Content type: Research

    Although there are several studies to investigate the association between blood lipids and microvascular complications, these studies reported conflicting results. The aim of the current study was to explore t...

    Authors: Hua Yang, Doris Young, Jian Gao, Yuanzhi Yuan, Minqian Shen, Yuan Zhang, Xueyan Duan, Shanzhu Zhu and Xiaoming Sun

    Citation: Lipids in Health and Disease 2019 18:18

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  11. Content type: Research

    Despite a large body of studies have demonstrated the multifaceted behavior of high-density lipoproteins (HDLs) in several physiological and pathological processes, the levels of plasma HDL-cholesterol (HDL-C)...

    Authors: Saibin Wang, Jingcheng Zhang and Xiaodong Lu

    Citation: Lipids in Health and Disease 2019 18:17

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  12. Content type: Research

    The immune-modulating potential of long-chain polyunsaturated fatty acids (LCPUFAs) based on their conversion into lipid mediators in inflammatory situations has been proven by several studies. Respecting the ...

    Authors: D. Fussbroich, K. Zimmermann, A. Göpel, O. Eickmeier, J. Trischler, S. Zielen, R. Schubert and C. Beermann

    Citation: Lipids in Health and Disease 2019 18:16

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  13. Content type: Research

    Polymorphisms have been identified to predispose to NAFLD. Here, we accessed the seven polymorphisms of rs1260326, rs780094 in GCKR, rs2954021 near TRIB1, rs2228603 in NCAN, rs58542926 in TM6SF2, rs12137855 ne...

    Authors: Wen Cai, Di-hua Weng, Ping Yan, Yu-ting Lin, Zheng-hui Dong, Mailamuguli and Hua Yao

    Citation: Lipids in Health and Disease 2019 18:14

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  14. Content type: Research

    Diabetes is often accompanied by dyslipidemia. Lipid control is very important in the management of diabetes. There are limited real world data on the lipid control in diabetic inpatients in southwest China.

    Authors: Qingtao Hou, Chuan Yu, Sheyu Li, Yun Li, Rui Zhang, Tao Zheng, Yi Ma, Miye Wang, Na Su, Ting Wu, Zhiwen Liu, Xia Sheng, Nan Li, Guanjian Liu, Yong Huang, Ting Xu…

    Citation: Lipids in Health and Disease 2019 18:13

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  15. Content type: Research

    Bioactive components of Ganoderma lucidum has recently gained intense research attention due to their acclaimed nutritional and medicinal properties. Thus, the terpenoid extract from the fruit bodies of G. lucidu...

    Authors: Olarewaju M. Oluba

    Citation: Lipids in Health and Disease 2019 18:12

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  16. Content type: Research

    Maonan nationality is a relatively conservative and isolated minority in the Southwest of China. Little is known about the association of endothelial lipase gene (LIPG) single nucleotide polymorphisms (SNPs) and ...

    Authors: Shuo Yang, Rui-Xing Yin, Liu Miao, Yong-Gang Zhou, Jie Wu and Qing-Hui Zhang

    Citation: Lipids in Health and Disease 2019 18:10

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  17. Content type: Research

    Studies have shown that non-traditional lipid profiles have a better association with stroke than traditional blood lipids in clinical applications, other studies have drawn different conclusions.

    Authors: Jia Zheng, Zhaoqing Sun, Xingang Zhang, Zhao Li, Xiaofan Guo, Yanxia Xie, Yingxian Sun and Liqiang Zheng

    Citation: Lipids in Health and Disease 2019 18:9

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  18. Content type: Research

    Obesity plays crucial roles in the pathogenesis of metabolic diseases such as hyperlipidemia, nonalcoholic fatty liver disease (NAFLD), and type 2 diabetes (T2D). The underlying mechanisms linking obesity to m...

    Authors: Junlong Wang, Linqiang Zhang, Ruyue Xiao, Yunhai Li, Shasha Liao, Zhiguo Zhang, Wenhui Yang and Bin Liang

    Citation: Lipids in Health and Disease 2019 18:8

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  19. Content type: Short report

    Lipids are implicated in the pathogenesis of age-related macular degeneration (AMD). The relationship between systemic lipids and AMD has not been well characterized. The objective was to investigate the relat...

    Authors: Richard D. Semba, Ruin Moaddel, Mary Frances Cotch, Fridbert Jonasson, Gudny Eiriksdottir, Tamara B. Harris, Lenore J. Launer, Kai Sun, Ronald Klein, Debra A. Schaumberg, Pálmi Jónsson, Vilmundur Gudnason and Luigi Ferrucci

    Citation: Lipids in Health and Disease 2019 18:7

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  20. Content type: Research

    To emphasize the mechanism of concurrent exercise effect on lipid disorders in insulin resistance (IR) and nonalcoholic fatty liver disease (NAFLD).

    Authors: Fan Zheng and Ying Cai

    Citation: Lipids in Health and Disease 2019 18:6

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  21. Content type: Research

    Coronary artery disease (CAD) is a multi-factor disease. Complement component 3 (C3) plays an important role in the development of CAD. The present study investigated the association between DNA methylation st...

    Authors: Gaojun Cai, Zhiying Huang, Lei Yu and Li Li

    Citation: Lipids in Health and Disease 2019 18:5

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  22. Content type: Research

    Serum lipids [total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and triglyceride (TG)] are risk factors for stroke, but the relationships between...

    Authors: Beiyu Zhao, Suhang Shang, Pei Li, Chen Chen, Liangjun Dang, Yu Jiang, Jin Wang, Kang Huo, Meiying Deng, Jingyi Wang and Qiumin Qu

    Citation: Lipids in Health and Disease 2019 18:4

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  23. Content type: Research

    The loss of muscle mass and concomitantly strength, poses a serious risk to the elderly and to astronauts. Dietary cholesterol (CL), in conjunction with resistance training (RT), has been strongly associated w...

    Authors: Teak V. Lee, Chang Woock Lee, Vincent C. W. Chen, Steve Bui, James D. Fluckey and Steven E. Riechman

    Citation: Lipids in Health and Disease 2019 18:3

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  24. Content type: Research

    ATP-binding cassette (ABC) transporters are involved in a huge range of physiological processes. Mutations in the ABCC6 gene cause pseudoxanthoma elasticum, a metabolic disease with progressive soft tissue calcif...

    Authors: Bettina Ibold, Isabel Faust, Janina Tiemann, Theo G. M. F. Gorgels, Arthur A. B. Bergen, Cornelius Knabbe and Doris Hendig

    Citation: Lipids in Health and Disease 2019 18:2

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  25. Content type: Research

    Excess energy intake contributes to metabolic disorders. However, the relationship between excess sugar and fat in their contributions to metabolic abnormalities remains to be further elucidated. Here we condu...

    Authors: Ke-Wei Wang, Bai-Quan Xiao, Bi-Hai Li, Yi-Yan Liu, Zhi-Yuan Wei, Jun-Hua Rao and Jian-Huan Chen

    Citation: Lipids in Health and Disease 2019 18:1

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  26. Content type: Research

    Excessive lipid depositing in liver cells could induce pathophysiological development of liver. Our study aimed to assess whether non-HDL cholesterol to HDL-cholesterol ratio (NonHDLc/HDLc) is an independent r...

    Authors: Tianhui An, Yi Song, Yi Yang, Mengyuan Guo, Hui Liu, Kun Liu and Zhaohui Wang

    Citation: Lipids in Health and Disease 2018 17:296

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  27. Content type: Short report

    Postprandial non-esterified fatty acid (NEFA) and triglyceride (TG) responses are increased in subjects with type 2 diabetes mellitus (T2DM) and may impair insulin action and increase risk of cardiovascular di...

    Authors: Amirsalar Samkani, Mads J. Skytte, Christian Anholm, Arne Astrup, Carolyn F. Deacon, Jens J. Holst, Sten Madsbad, Ray Boston, Thure Krarup and Steen B. Haugaard

    Citation: Lipids in Health and Disease 2018 17:295

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  28. Content type: Research

    Recent research had shown blood glucose was not the only cause of large for gestational age infant (LGA), the contributions of other fuels such as lipids also play an important role in fetal development. Howev...

    Authors: Ning Liang, Haiyan Zhu, Xueping Cai, Zhiyin Le, Hongliang Wang, Dian He, Rong Xiao and Huanling Yu

    Citation: Lipids in Health and Disease 2018 17:294

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  29. Content type: Research

    Inflammation may be a key pathophysiological mechanism in diabetic nephropathy (DN). Intercellular adhesion molecule 1 (ICAM1) is an acute phase marker of inflammation. ICAM1 rs5498 has been reported to be ass...

    Authors: Liya Liu, Dongling He, Ling Fang and Xiaojie Yan

    Citation: Lipids in Health and Disease 2018 17:293

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  30. Content type: Research

    The hepatokine fetuin-A is linked to obesity and type 2 diabetes, but its presence and expression in adipose tissue remain unclear. In this study, we aimed to assess the circulating levels of fetuin-A and its ...

    Authors: Abdelkrim Khadir, Sina Kavalakatt, Dhanya Madhu, Maha Hammad, Sriraman Devarajan, Jaakko Tuomilehto and Ali Tiss

    Citation: Lipids in Health and Disease 2018 17:291

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  31. Content type: Research

    Long-term statin therapy has been shown to protect against several cancers, including esophageal cancer (EC). While the mechanisms underlying this effect are not clear. We investigated the effect of hydrophobi...

    Authors: Yan Chen, Li-Bin Li, Jun Zhang, Du-Peng Tang, Jing-Jing Wei and Ze-Hao Zhuang

    Citation: Lipids in Health and Disease 2018 17:290

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  32. Content type: Research

    The present study evaluated the predictive ability of five known “best” obesity and lipid-related parameters, including body mass index (BMI), waist-to-height ratio (WHtR), triglyceride-to-high-density-lipopro...

    Authors: Zhan Gu, Ping Zhu, Qiao Wang, Huayu He, Jingjuan Xu, Li Zhang, Dong Li, Jianying Wang, Xiaojuan Hu, Guang Ji, Lei Zhang and Baocheng Liu

    Citation: Lipids in Health and Disease 2018 17:289

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  33. Content type: Research

    Hyperuricemia is related to obesity and fat accumulation. This study aimed to observe the effects of laparoscopic sleeve gastrectomy (LSG) on serum uric acid (sUA) level and body fat distribution in obese pati...

    Authors: Xuane Zhang, Cuiling Zhu, Jingyang Gao, Fangyun Mei, Jiajing Yin, Le Bu, Xiaoyun Cheng, Chunjun Sheng and Shen Qu

    Citation: Lipids in Health and Disease 2018 17:288

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  34. Content type: Research

    Krill powder is rich in bioactive ingredients such as eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), phospholipids, protein and astaxanthin. Containing dominantly EPA, it is considered to be effectiv...

    Authors: Essi S. Sarkkinen, Markku J. Savolainen, Jyrki Taurio, Tuuli Marvola and Inge Bruheim

    Citation: Lipids in Health and Disease 2018 17:287

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  35. Content type: Research

    Recently, trimethylamine-N-oxide (TMAO) plasma levels have been proved to be associated with atherosclerosis development. Among the targets aimed to ameliorating atherosclerotic lesions, inducing bile acid syn...

    Authors: Lin Ding, Mengru Chang, Ying Guo, Lingyu Zhang, Changhu Xue, Teruyoshi Yanagita, Tiantian Zhang and Yuming Wang

    Citation: Lipids in Health and Disease 2018 17:286

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  36. Content type: Research

    The focus of studies on high-density lipoproteins (HDL) has shifted from HDL-cholesterol (HDL-C) to HDL function. We recently demonstrated that low USF1 expression in mice and humans associates with high plasma H...

    Authors: Maija Ruuth, Jarkko Soronen, Essi Kaiharju, Krista Merikanto, Julia Perttilä, Jari Metso, Miriam Lee-Rueckert, Marja-Riitta Taskinen, Petri T. Kovanen, Katariina Öörni, Vesa M. Olkkonen, Matti S. Jauhiainen and Pirkka-Pekka Laurila

    Citation: Lipids in Health and Disease 2018 17:285

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  37. Content type: Research

    The atherogenic index of plasma showed to be related with some chronic disease like cardiovascular diseases and atherosclerosis. Body mass index which was commonly used in clinical practice is not an accurate ...

    Authors: Qian WANG, Dongmei Zheng, Jia Liu, Li FANG and Qiu Li

    Citation: Lipids in Health and Disease 2018 17:284

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  38. Content type: Research

    Diabetes mellitus is a non-infectious disease that has a high prevalence worldwide. Altered level of many haematological parameters have been observed in patients with diabetes. The levels of lipids are also a...

    Authors: Samuel Antwi-Baffour, Ransford Kyeremeh, Samuel Owusu Boateng, Lawrence Annison and Mahmood Abdulai Seidu

    Citation: Lipids in Health and Disease 2018 17:283

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  39. Content type: Research

    Designer eggs (DEs) have gained positive importance in maintaining cholesterol level, triglyceride profile and protection towards cardiovascular diseases due to the presence of essential fatty acids (EFAs) suc...

    Authors: Amna Javed, Muhammad Imran, Nazir Ahmad and Abdullah Ijaz Hussain

    Citation: Lipids in Health and Disease 2018 17:282

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  40. Content type: Research

    Several meta-analyses have demonstrated that the rs662 polymorphism in Paraoxonase 1 gene (PON1) gene is associated with coronary heart disease (CHD). However, it is still uncertain whether this polymorphism is a...

    Authors: Zhi Luo, Lijun Pu, Irfan Muhammad, Yun Chen and Xiaoqian Sun

    Citation: Lipids in Health and Disease 2018 17:281

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  41. Content type: Research

    Extracts from plants, rich in antioxidants may be used as active ingredients of many preparations, mainly due to their antioxidant, regenerative and anti-aging properties. The work involved a comprehensive eva...

    Authors: Zofia Nizioł-Łukaszewska, Dominika Furman-Toczek and Martyna Zagórska-Dziok

    Citation: Lipids in Health and Disease 2018 17:280

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  42. Content type: Research

    Hyperlipidemia is a well-established risk factor for cardiac damage, which can lead to cardiovascular diseases. Many studies have shown that Coenzyme Q10(CoQ10) protects against cardiac damage in vivo. The aim of...

    Authors: Xiaoqing Zhang, Hongyang Liu, Yuhua Hao, Lulu Xu, Tiemei Zhang, Yingshu Liu, Lipeng Guo, Liyue Zhu and Zuowei Pei

    Citation: Lipids in Health and Disease 2018 17:279

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  43. Content type: Research

    High blood lipoprotein concentrations are one of the major risk factors for cardiovascular diseases. Drug therapy is the base of treatment; statins in particular. Both brand-name and generic presentations are ...

    Authors: A. Sicras-Mainar, L. Sánchez-Álvarez, R. Navarro-Artieda and J. Darbà

    Citation: Lipids in Health and Disease 2018 17:277

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  44. Content type: Research

    An increasing number of studies have shown that obesity is the key etiological agent of cardiovascular diseases, nonalcoholic fatty liver disease, type 2 diabetes and several kinds of cancer and that gut micro...

    Authors: Yanan An, Yan Li, Xueyan Wang, Zhaobin Chen, Hongyue Xu, Lingyu Wu, Shulin Li, Chao Wang, Wenjing Luan, Xuefei Wang, Mingyuan Liu, Xudong Tang and Lu Yu

    Citation: Lipids in Health and Disease 2018 17:276

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  45. Content type: Research

    Previous studies have investigated the associations of paraoxonase 1 (PON1) rs854560 polymorphism with plasma lipid levels, but the results are inconclusive. This meta-analysis aimed to clarify the associations o...

    Authors: Zhi Luo, Shujin Li, Irfan Muhammad, Md Rezaul Karim and Yongyan Song

    Citation: Lipids in Health and Disease 2018 17:274

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